How Fast Will Oral spironolactone Drop My Testosterone Levels?

[Zoro]

I'm due to get my topical estrogen any day now

What product are you using for topical estrogen? I'm using Alpicort as part of my vehicle for my RU mixture but I'm not too keen on using it for an extended period of time because of the corticosteroids

 

[Zoro]

Yeah look I’m not going to lie. I’ve given myself another year to see if anything gets better and if it doesn’t I’m just gonna neck myself. I’m not prepared to live the rest of
My life feeling as desperately ugly and sad as I do now. I’m only 24. I’m single. I won’t find anyone if I go bald, I won’t have the confidence to ever be social again, I will always be insecure and depressed about it.
So I’m going to try darolutamide for a year, and if that’s a bust, then so am I, and I’m cool with that decision.

Not trying to downplay your hair loss but I was expecting a wispy bird's nest-tier diffuse thinning, I wouldn't have noticed any thinning if there wasn't a second pic to compare to. Diffuse thinning is f*****g sh*t though, it seems like it's harder to treat compared to traditional hairline recession unless you catch it very early, not to mention it makes getting a transplant more complicated as well.

 

[Georgie]

Not trying to downplay your hair loss but I was expecting a wispy bird's nest-tier diffuse thinning, I wouldn't have noticed any thinning if there wasn't a second pic to compare to. Diffuse thinning is f*****g sh*t though, it seems like it's harder to treat compared to traditional hairline recession unless you catch it very early, not to mention it makes getting a transplant more complicated as well.

Kinda means I’m left with f*** all options of medications fail. So far minoxidil, spironolactone, the pill/cyproterone acetate have failed me, avodart and ru are currently also failing badly.

 

[AnxiousAndy]

Can you show us what does your hair look like? And how old are you

I've already uploaded pics, go to my profile and the threads I've started you will find them there. I'm 20 and Norwood 2. 2

 

[AnxiousAndy]

What product are you using for topical estrogen? I'm using Alpicort as part of my vehicle for my RU mixture but I'm not too keen on using it for an extended period of time because of the corticosteroids

Its generic oestradiol gel 60mg of 17b estradiol in 80g tube.

 

[doyle11]

Yeah look I’m not going to lie. I’ve given myself another year to see if anything gets better and if it doesn’t I’m just gonna neck myself. I’m not prepared to live the rest of
My life feeling as desperately ugly and sad as I do now. I’m only 24. I’m single. I won’t find anyone if I go bald, I won’t have the confidence to ever be social again, I will always be insecure and depressed about it.
So I’m going to try darolutamide for a year, and if that’s a bust, then so am I, and I’m cool with that decision.

Made me a little sad reading this post. For What it's worth my girlfriends have lost hair density while I have been with them. My fiance has similar hair to you and i dont really notice it until i look at teens/ children hair. I think a lot of people lose that juvenile density when they exit their teens, even women.

You're clearly an intelligent, attractive woman with a lot going for you. I hope you overcome your hair loss

 

[IdealForehead]

Because I'm not ridiculously wealthy.

Hey Andy,

Tough regimen you're looking at. I was taking similar orals (spironolactone/cypro) when I switched over to daro. Daro is not TOO expensive.

$500 USD for 1 gram.
5 mg /day (more than adequate dose for me)
= $2.50 USD per day

Can't you get a job or some tiny source of supplemental income to pay that? I don't think most people should use daro but if you're talking MTF transition vs. daro, daro is by far the cleaner and safer choice.

 

[IdealForehead]

I take the highest dose contraceptive pill. It’s banned in many countries because it has given women strokes and cancer.
I have also lost 80% of my hair in three years. It’s fast progressing. I don’t like being alive as it is. The thought of living this way forever makes me sick in the pit of my stomach.

Yeah look I’m not going to lie. I’ve given myself another year to see if anything gets better and if it doesn’t I’m just gonna neck myself. I’m not prepared to live the rest of
My life feeling as desperately ugly and sad as I do now. I’m only 24. I’m single. I won’t find anyone if I go bald, I won’t have the confidence to ever be social again, I will always be insecure and depressed about it.
So I’m going to try darolutamide for a year, and if that’s a bust, then so am I, and I’m cool with that decision.

I hope you won't mind me saying some things we've talked about again. Sorry if I'm repeating myself. But if this is what you've decided your life is going to balanced on, then let's at least make the best effort we can.

In your case, I'm glad you've gone to daro because it is the strongest anti-androgenic therapy possible, and using it topically avoids nuking your systemic androgens too much. So despite its strength, it should be much cleaner than the heavy oral drugs you've already done (like spironolactone). I do think this will 100% solve any androgenic component of your hair loss. I think it's physically impossible for it not to.

However, I don't think that's nearly enough. It is still absolutely essential you solve your estrogen/progesterone issue properly, and do it immediately. Diane 35 is not a good hormone replacement therapy for someone in early menopause. It's composed of extremely powerful artificial synthetic hormones that don't come close to replicate the natural balance of your ideal female hormones.

Again, the fact that you have diffuse full body hair loss (not just on your head) guarantees this is far more than just androgenic loss, as hyperandrogenism causes an increase in body hair in women, not loss. This is also suggested by the fact that you say your hair growth "stalls" for periods of time. This is also not typical of androgenic hair loss. However, we know that severe estrogen/progesterone imbalances (either too much or too little) can cause both problems.

Please for your sake do your best to get on the bioidentical hormones ASAP. Don't wait another 2-3 months. Call a new clinic and do it now. Time is short. Your hair will most likely keep shedding until you do.

Daro won't stop this since that's only one part of the problem. I would guess from everything you've said the estrogen issue is at least ~70% of the problem. That body hair loss and stalling hair growth can only be from a nonandrogenic type of hormone imbalance. Given what we know of estrogen excess impairing hair growth, Diane 35 may in fact be making this much worse.

Lastly, I know you won't believe me at your core, but I absolutely believe what everyone else has said as well. Even if you went bald and wore a wig, personally, I wouldn't care much. Lots of guys wouldn't. But I think at the center, this is more about your self-image and a difficulty with the loss of that in the context of how you were brought up and what you've been through. Plus hair loss is just objectively difficult for almost anyone to cope with.

I hope you get your hair back. I absolutely think it's possible. Fundamentally, this is just about blocking undesirable hormones at the scalp and adding back the ones you need through the body in the right balance. It isn't rocket science. It should be solvable. But if for any reason it still proves difficult, I hope you will find yourself more resilient than you believe you are now.

 

[Sameerahmed7]

I've already uploaded pics, go to my profile and the threads I've started you will find them there. I'm 20 and Norwood 2. 2

I saw your pics from November. You are Norwood 2 and have pretty decent density. Given you haven't lost 40% of your hair in the last 3 months, you shouldn't go this harsh on your treatments. Maybe stick to finasteride only. Just my opinion

 

[Mutaher Zawar Syed]

I used finasteride for a week. I noticed side effects Of shrinking of my testicles size and they became soft, also noticed pain. I stopped using finasteride after reading horror stories on internet after just a week of finasteride usage. When I stopped using finasteride, I noticed swelling in one of my testicles for almost a week, the swelling usually came and gone. Then after a week of stopping finasteride, I noticed decrease in hair loss. When I used to shower my hairs before using finasteride, I noticed approx 20 hairs loss. But after using finasteride, I used to notice maximum one hair loss during shower. For a month, there was no semen in ejaculation-dry orgasm. Then I recovered, my testicles became firm again. And After three months, I am totally recovered. Is it normal? Does it happen to everyone? I am thinking to start finasteride again due to its stopping hair loss. Should I?

 

[AnxiousAndy]

Hey Andy,

Tough regimen you're looking at. I was taking similar orals (spironolactone/cypro) when I switched over to daro. Daro is not TOO expensive.

$500 USD for 1 gram.
5 mg /day (more than adequate dose for me)
= $2.50 USD per day

Can't you get a job or some tiny source of supplemental income to pay that? I don't think most people should use daro but if you're talking MTF transition vs. daro, daro is by far the cleaner and safer choice.

Got a job interview in a couple of weeks so hopefully it goes well. I live in a small town so work is hard to come by. Where can I go about purchasing daro? Also are you experiencing regrowth from it?

 

[AnxiousAndy]

I used finasteride for a week. I noticed side effects Of shrinking of my testicles size and they became soft, also noticed pain. I stopped using finasteride after reading horror stories on internet after just a week of finasteride usage. When I stopped using finasteride, I noticed swelling in one of my testicles for almost a week, the swelling usually came and gone. Then after a week of stopping finasteride, I noticed decrease in hair loss. When I used to shower my hairs before using finasteride, I noticed approx 20 hairs loss. But after using finasteride, I used to notice maximum one hair loss during shower. For a month, there was no semen in ejaculation-dry orgasm. Then I recovered, my testicles became firm again. And After three months, I am totally recovered. Is it normal? Does it happen to everyone? I am thinking to start finasteride again due to its stopping hair loss. Should I?

I wouldn't say that is normal but if you want to try finasteride again I would take half a tablet daily instead and see if you fare better on that.
@Sameerahmed7 Unfortunately finasteride isn't enough to stop my hair loss, that pic I posted was a year into it and a few months into oral minoxidil before I started shedding so my hair is a bit worse now. I'm trying to find a sweet spot in my new regimen where I can maximise hair gains and minimise side effects. I don't mind some gyno, hair is more important to me.

 

[Jesse Navarro]

The most dangerous side effects will show up after a long term use, right? I don't mean gynecomastia, i'm thinking about cancer and liver or kidney problems. Maybe two years on this regimen wont cause the most dangerous. What do you think?

 

[AnxiousAndy]

The most dangerous side effects will show up after a long term use, right? I don't mean gynecomastia, i'm thinking about cancer and liver or kidney problems. Maybe two years on this regimen wont cause the most dangerous. What do you think?

If we stick to only using topical that is a very low dose compared to what trans people take ( 8mg oral estradiol with 200mg spironolactone/50mg Androcur + finasteride/dutasteride )
Hopefully my estrogel will arrive today. How has it been for you so far Jesse? Noticed decrease of shedding? Any regrowth yet?

 

[Jesse Navarro]

If we stick to only using topical that is a very low dose compared to what trans people take ( 8mg oral estradiol with 200mg spironolactone/50mg Androcur + finasteride/dutasteride )
Hopefully my estrogel will arrive today. How has it been for you so far Jesse? Noticed decrease of shedding? Any regrowth yet?

I noticed a decrease of shedding, and my scalp fells more healthy, no more sore spots. And it is more dry, which is great because i had a very oily scalp. No regrowth yet, but it's been only a month on spironolactone and ten days on estrogel. I looks like my temple points are more dense, but its hard to tell. I was losing my temple points, that was what freaked me out.

 

[Jesse Navarro]

One thing i can be sure is that my hair loss havent advanced since i started.

 

[AnxiousAndy]

One thing i can be sure is that my hair loss havent advanced since i started.

Glad to hear buddy My temples are already decimated and hairline has receded a decent amount, it's even creeping towards my forelock  :damn: hope to bring that back a bit and stabilise. Do you use the estrogel everyday?

 

[Jesse Navarro]

Glad to hear buddy My temples are already decimated and hairline has receded a decent amount, it's even creeping towards my forelock  :damn: hope to bring that back a bit and stabilise. Do you use the estrogel everyday?

Everyday. Im expecting regrowth also. Such a harsh regimen is worth only to see some regrowth. Hope it will work for both of us, until some new treatment comes.

 

[AnxiousAndy]

Everyday. Im expecting regrowth also. Such a harsh regimen is worth only to see some regrowth. Hope it will work for both of us, until some new treatment comes.

Good, I will be doing same. Yea it sucks that it's somewhat of a hardcore regimen but if it works then it works Hopefully we will have something effective and safer in 5 years.

 

[ams98]

Haha. I gotta show you the photo. First one is 9 months on spironolactone, second is last November after being off it for almost 2 years. Also I’m dying a little bit inside at how
much more hair I had in both of these photos. f***.

Damn bae, lemme Tap zat *** lol