Italian Hair Loss Lotion To Hit The Market In 2016

[gagost02]

So let me get this straight, sorry for my intelligence on the creation of this lotion. Please correct me if I'm wrong but in order to create this lotion for "research purposes", all you have to do is follow the steps listed below, according to the patent:

"Three solutions are prepared as follows: 1 m! of equal is diluted in 1 ml of ethanol and the solution is brought to 10 ml with water;

1 mg of PGE1 in 1 ml of ethanol brought to 10 ml with water;


The above three solutions are placed in a sonicator together with 10 g of phosphatidylcholine (Lipid S75 Human-grade) and sonicated for a sufficient time to obtain liposomes with diameter of less than 100 nm.

The liposome solution thus obtained is poured into an aqueous solution of polylysine 40 - 100 MW (0.01 mg/10 ml) and constantly stirred for 30 minutes."



PGE1: http://drs-labs.com/lipid-compounds/27-buy-pge1-caverject-alprostadil-caprodil-uk.html

Water: Your sink, etc.

Ethanol: http://www.sigmaaldrich.com/catalog/product/sigald/459844?lang=en&region=US

Phosphatidylcholine: http://www.professionalsupplementce...UxBCeCc7lCk0YDIOggO9xZsXmhrV4iUYq9hoCrt7w_wcB

Polylysine 40-100 MW: http://www.alamanda-polymers.com/homopolypeptides/poly-L-lysine-succinylated

Sonicator: https://homogenizers.net/products/q...F6rvsKqdAHi_sq7dyl6Z8EDeUyM2tQe6INxoCtk7w_wcB


source: https://www.google.com/patents/WO2013171668A1?cl=en

The exact patent:
http://www.google.com/patents/WO2015170247A1?cl=en&hair loss=it

Thread "Make brotzu's lotion (not yet GB!)":
https://www.hairlosstalk.com/interact/threads/make-brotzus-lotion-not-yet-gb.98462/

First part:
At the bottom of that link is written that the best recipe is that used in group A.
Let's list every ingredient and how much can it cost.
Its composition is:
-Phosphatidylcholine (Lipid S75 Humangrade) 1 g
-DGLA 1.25 mg
-S-Equol 7 mg
-Ethanol 1 ml
-L-propionylcarnitine 7 mg
-Stearylamine 30 mg------>( 10 mg is less effective, if you read all you will see it!) <----Please someone check what's the best quantity: 10 or 30 mg?
-Sterile water 5 m

DGLA, S-equol and stearylamine are dissolved in the dose of ethanol and phosphatidylcholine is added to the solution. Propionylcarnitine is dissolved in 5 ml of water and the thus obtained solution is added to the previous one. The resulting mixture is placed in a sonicator (Sonipress 150 kw) and submitted to 25 sonication cycles. Each cycle is composed of 5 seconds of full power sonication alternating with 2 seconds of rest. The lotion thus obtained is divided into 5 vials and each one is brought to the volume of 7 ml with additional sterile water. The lotion thus obtained is ready for use.

 

[kuba197]

It is not easy to replicate 'the real' lozione. Patent doesnt give all guidelines.

 

[Xander94]

Italian anouncement says it will take until 2018 so I think we got to wait

 

[That Guy]

But the pics were crap... Results of the study in terms of "bueno"...
Don't get me wrong, I hope it works but until we have real evidence we have every right to doubt it. Always sounds weird to me it could work for AA and Androgenetic Alopecia. Still hope it could, though.

Pics looked fine to me, certainly not the best, but people say pics are crap no matter what.

Mark my words, when Tsuji releases pics from his trial, they could be ultra high resolution, better than real life definition and colours, with Hollywood grade lighting and people will still say it's sh*t; toppik, combover, etc.

 

[Jake lake]

No matter what the outcome of this product will be, I kind of think they missed their window of opportunity.

The product candidate will be developed by 2018. Which means actual release might be 2018-2019. I hope that by then some other products of the pipeline will be released and equally good.

 

[Bklyn_23]

It's actually unreal that apparently Brotzu had a WORKING LOTION that was by all accounts safe and effective and then it ends up in the hands of big pharma (or medium pharma at least) and all of a sudden we're looking at 1.5+ years until release even though they've already completed trials. Wow.

 

[Xander94]

It's actually unreal that apparently Brotzu had a WORKING LOTION that was by all accounts safe and effective and then it ends up in the hands of big pharma (or medium pharma at least) and all of a sudden we're looking at 1.5+ years until release even though they've already completed trials. Wow.

Welcome to Big Pharma the worst industry in the world.

 

[Grasshüpfer]

It's actually unreal that apparently Brotzu had a WORKING LOTION that was by all accounts safe and effective and then it ends up in the hands of big pharma (or medium pharma at least) and all of a sudden we're looking at 1.5+ years until release even though they've already completed trials. Wow.

1. The patent of the lotion is not a recipe. It contains plain wrong information to keep Chinese labs from bootlegging.

2. To upscale the production to industrial amounts of lotion takes at least one year, not to speak of actually organising sales ect. Each hand crafted bottle of lotion from the trial is probably worth 500€

Fidia is doing everything right. Don't be a b**ch about it.

 

[fr3z]

even though they've already completed trials

wake up boi, they haven't completed anything yet

we announce that the study is still in progress

 

[Roberto_72]

Pics looked fine to me, certainly not the best, but people say pics are crap no matter what.

Mark my words, when Tsuji releases pics from his trial, they could be ultra high resolution, better than real life definition and colours, with Hollywood grade lighting and people will still say it's sh*t; toppik, combover, etc.

This reminds me when Obama released is Hawaiian birth certificate after all the "birthers" had pestered him for five/six years.

Of course "birthers" said immediately that the PDF was a fake.

 

[MomoGee]

No matter what the outcome of this product will be, I kind of think they missed their window of opportunity.

The product candidate will be developed by 2018. Which means actual release might be 2018-2019. I hope that by then some other products of the pipeline will be released and equally good.

This. They went from competing with Minoxidil and Finasteride to the soon to be released Histogen and Replicel.

 

[Jake lake]

This. They went from competing with Minoxidil and Finasteride to the soon to be released Histogen and Replicel.

Yeah, this product was mainly hyped since we saw it as the first one to come out. However, this is not the case anymore and therefore the yes/no discussion loses relevance.

There are a lot of horses in the race right now with release dates closely packed together, at some point, one of them has got to finish right. Otherwise f*** me

 

[Xander94]

So that was it ? We are going bald?

 

[Jake lake]

So that was it ? We are going bald?

lol, no, it just means we have to stop focussin' on this and start focussing on the array of products peeking at the window (https://www.hairlosstalk.com/pipeline/) around 2018-2019.

 

[wilfred]

lol, no, it just means we have to stop focussin' on this and start focussing on the array of products peeking at the window (https://www.hairlosstalk.com/pipeline/) around 2018-2019.

My money is on Histogen. They are doing on right in my opinion, aligning with countries such as China and Mexico to expedite commercialization.

 

[irishlad87]

In one way i wish i never discovered this forum as i came into work 2 days in the last year expecting some concrete good news with samumed and brotzu and both times been let down. Realistically for nw3 guys and worse, we are kinda screwed as finasteride does nothing for more people than you may think. However maybe when fidia says by 2018 they mean we will have news in autumn and product at start of 2018 that can turn my frown upside down ha.

 

[hairblues]

In one way i wish i never discovered this forum as i came into work 2 days in the last year expecting some concrete good news with samumed and brotzu and both times been let down. Realistically for nw3 guys and worse, we are kinda screwed as finasteride does nothing for more people than you may think. However maybe when fidia says by 2018 they mean we will have news in autumn and product at start of 2018 that can turn my frown upside down ha.

i thought this too and then one of the italian members did a better interpretation and i did not get impression it will be 2017..but hopefully i am wrong.

 

[irishlad87]

i thought this too and then one of the italian members did a better interpretation and i did not get impression it will be 2017..but hopefully i am wrong.

Fcuk ha

 

[hairblues]

Fcuk ha

yeah you can look back a few pages think it was 7th sense who did a more proper interpretation of the last sentence.
he seemed to think they mean in 2018. He was much more detailed about it he wrote several paragraphs.

 

[Folliman]

Guys, why don't you open a GB for miconazole? It's literally PGE1, the active ingredient that promotes hair growth.