Italian Hair Loss Lotion To Hit The Market In 2016

[yellowbluegrey]

In theory, everything that inhibits DHT can give you manboobs. It depends on dosage.

Do you think this + finasteride would be safe? I mean, people take finasteride and dutasteride together with no sides

 

[kuba197]

In theory, everything that inhibits DHT can give you manboobs. It depends on dosage.

I thought that increase in estrogen cause gyno.
And what a risk from Brotzu and his team. They mess in kids' hormones...

 

[Drogedagh]

http://ajcn.nutrition.org/content/81/5/1072.full

We recently showed that S-equol is unique in that it not only possesses estrogenic properties but also is a potent antagonist of dihydrotestosterone in vivo, which has significant implications for the prevention of prostate cancer and other androgen-related conditions (22). We can find no other example of a molecule that is both a selective estrogen and an androgen antagonist

Competitive binding studies were used to assess the estrogenic properties of R- and S-equol. On the basis of the ability of R- and S-equol to compete with [3H]E2 in ER binding, their affinities for ERs translated in vitro were shown to be very different. S-equol showed the greatest affinity for ERβ (Ki = 0.73 ± 0.2 nmol/L), whereas its affinity for ERα (Ki = 6.41 ± 1 nmol/L) was relatively poor. In contrast, R-equol possessed only 4.8% and 25.0% as much relative binding affinity, respectively, for ERβ (Ki = 15.4 ± 1.3 nmol/L) and for ERα (Ki = 27.38 ± 3.8 nmol/L) as did S-equol. For comparison, 17β-estradiol binds ERα with a Kd of 0.13 nmol and ERβ with a Kd of 0.15 nmol. S-equol thus shows ER selectivity with a high affinity for ERβ, whereas R-equol can, at best, be classified as a weak estrogen.

 

[kuba197]

So if it might cause gyno it also will cause problems with erection, morning wood etc. Thats obvious.

 

[bags]

Well this explains why I'm always fatigued and my CNS burns out insanely fast during workouts......

http://www.bodybuilding.com/fun/reform8.htm

For f*** sakes can we just get something that doesn't f*** with our hormones........

At this rate Histogen Replicel and Tsuji cannot come fast enough. I just want hair that does not fall out! f***! God why can't my hair just be DHT resistant!!!

 

[bags]

Well this explains why I'm always fatigued and my CNS burns out insanely fast during workouts......

http://www.bodybuilding.com/fun/reform8.htm

For f*** sakes can we just get something that doesn't f*** with our hormones........

At this rate Histogen Replicel and Tsuji cannot come fast enough. I just want hair that does not fall out! f***! God why can't my hair just be DHT resistant!!!

I have never wanted to do steroids but man more and more everyday I'm thinking just take finasteride or some sh*t and live on Anavar to counter all the sexual sides until this sh*t gets figured out!! Smfh!! By then I'll probably be hooked anyways and take a good chunk of my life off the timeline but hey. All because balding right?

 

[Drogedagh]

So if it might cause gyno it also will cause problems with erection, morning wood etc. Thats obvious.

isn't gyno caused by high estrogen? S-equol lowers it

 

[big_head]

Did you actually read what I wrote? Where did I mention Phytoestrogens? The guy in the publication was drinking 3 litres of soy milk a day, one cup of soy milk has around 30mg of soy isoflavone. If that isoflavone is mainly daidzein and you have the bacteria present, then you're going to be generating shitloads of S-Equol and decimating any DHT in your body and we know about the side affects possible from finasteride and dutasteride.

So no, it's not BS and not faulty reasoning as I never said eating soy will give you man boobs.

Did you watch the video? ISOFLAVONES ARE CONCENTRATED PHYTOESTROGENS. Put that in caps and bold so you understand.

Watch the video, it addresses the soy milk and isoflavone controversy as well, with plenty of scientific sources. 3 litres of soy milk equates to about the amount of isoflavones in a half can of soy beans. It's mostly water. Soy isoflavones do not affect your hormones as they are plant estrogens which equate to incredibly weak estrogen LIKE compounds. If you would like to ingest mammalian estrogens, I suggest you drink cow's milk (notice there is no estrogen scare over cow milk despite it having lots of estrogen).

So again, soy does not affect your hormones. It's all been debunked countless times. That one study that people site is a single case and they never even determined if the soy was what gave him breasts. Yet it is the single study that has spawned this completely silly and paranoid campaign against soy.

 

[Drogedagh]

As I understand s-equol oral intake is useful only in case if hair loss is caused by high amount of DHT in a bloodstream. In case if hair follicles are just too sensitive to DHT in general - s-equol oral intake is useless. S-equol will lower DHT amount in bloodstream, but follicles are still sensitive to it anyway.

 

[Xaser94]

Can anyone else vouch for Fidia supposedly releasing new news at the end of the Summer. One user apparently got an email stating as such, but its weird if they didnt send that email to others as companies usually send generic responses.

 

[papa pinrel]

so finnalyy this could give sides as finasteride?

 

[jc3303]

There's no way this will have sides like finasteride, it was used on women and children so obviously it doesn't affect hormones nearly as much as finasteride.

On a side note anyone here know when those Italians are going to be done making their brotzu lotion? I'm dying to know if this actually works

 

[Blackber]

There's no way this will have sides like finasteride, it was used on women and children so obviously it doesn't affect hormones nearly as much as finasteride.

On a side note anyone here know when those Italians are going to be done making their brotzu lotion? I'm dying to know if this actually works

I agree with this line of thinking. Aren't women extremely sensitive to DHT inhibitors - finasteride's warning labels state they can't even touch the pills when pregnant. If that's the case I would think the fact that it's been used on women and children with AA is an indicator it should be fairly safe.

 

[Afro_Vacancy]

A lot of Asians produce a lot of equol, yet not many Asian boys are born without penises.

So different sides than finasteride/dutasteride.

 

[mr_robot]

Did you watch the video? ISOFLAVONES ARE CONCENTRATED PHYTOESTROGENS. Put that in caps and bold so you understand.

Watch the video, it addresses the soy milk and isoflavone controversy as well, with plenty of scientific sources. 3 litres of soy milk equates to about the amount of isoflavones in a half can of soy beans. It's mostly water. Soy isoflavones do not affect your hormones as they are plant estrogens which equate to incredibly weak estrogen LIKE compounds. If you would like to ingest mammalian estrogens, I suggest you drink cow's milk (notice there is no estrogen scare over cow milk despite it having lots of estrogen).

So again, soy does not affect your hormones. It's all been debunked countless times. That one study that people site is a single case and they never even determined if the soy was what gave him breasts. Yet it is the single study that has spawned this completely silly and paranoid campaign against soy.

Again, read what I wrote, I never said soy isoflavones affected hormones due to estrogen mimicing, I said DHT inhibition as a consequence of S-Equol, nothing to do with estrogen. I don't care if people eat soy or not, what I do care about is if taking S-Equol orally could have any side affects.

 

[mr_robot]

I agree with this line of thinking. Aren't women extremely sensitive to DHT inhibitors - finasteride's warning labels state they can't even touch the pills when pregnant. If that's the case I would think the fact that it's been used on women and children with AA is an indicator it should be fairly safe.

5aR inhibitors and DHT inhibitors are n't the same thing.

 

[mr_robot]

A lot of Asians produce a lot of equol, yet not many Asian boys are born without penises.

So different sides than finasteride/dutasteride.

If you have been producing s-equol from a young age it is likely that your body would start to generate a tolerance to it.

Regardless this is topical and the amount specified in the formula is 7mg to make a months worth of lotion. That works to around 0.25mg per application with a fraction of that amount being absorbed into the skin let alone any going systemic. So no, for a topical application you are not going to get any finasteride/dutasteride side affects.

 

[yellowbluegrey]

If you have been producing s-equol from a young age it is likely that your body would start to generate a tolerance to it.

Regardless this is topical and the amount specified in the formula is 7mg to make a months worth of lotion. That works to around 0.25mg per application with a fraction of that amount being absorbed into the skin let alone any going systemic. So no, for a topical application you are not going to get any finasteride/dutasteride side affects.

Good to know; was a little concerned I wouldn't be able to use the lotion as I'm on finasteride. Would be dumb if you think about it; they have to know that a big chunk of people who are gonna use this will already be on finasteride / dutasteride

 

[Afro_Vacancy]

How do we know that 0.25 mg is very little? What's the scale?

 

[Dench57]

If you have been producing s-equol from a young age it is likely that your body would start to generate a tolerance to it.

Regardless this is topical and the amount specified in the formula is 7mg to make a months worth of lotion. That works to around 0.25mg per application

lol wat

that's ridiculously small. there were huge threads years ago with people taking 30mg+ daily of s-equol, either oral or topical, with no results. I wonder if this "cationic liposome" vehicle will make the difference.