Kintor Pharmaceuticals Furthers Baldness Treatment Drugs In Us And China

[Ralph Wiggum]

How effective is Kintor's product expected to be compared to what's already on the market?

 

[trialAcc]

How effective is Kintor's product expected to be compared to what's already on the market?

There is nothing like it actually on the market, so I guess infinitely?

But seriously we need to wait on the phase 2 results. It's probably going to be somewhere between RU and finasteride in terms of pure efficacy but I doubt it will have the ability to maintain as long as finasteride.

 

[Cardinal~]

What's the difference between the three trials? Do they upper the dose or something of the sort?

 

[Chads don't bald]

doubt it will have the ability to maintain as long as finasteride.

Why do you say that?

Is it best to use both finasteride and this together?

 

[Isneezedsohard]

Very promising news indeed. Only personal concern is that while I trust they can follow deadlines, it still forces me to put off other potent treatments such as OM, RU or nuclear cycles. It would just be silly to hit the kitchen sink with something safe like KX just around the corner, but not sure how long this lousy NW2 has on Finas alone. This, along with their protac better be worth the wait cause it's the last hype train I'm boarding, and it's got till next year to take off.

I almost feel like I might as well stick with RU for now, nice I can switch to pyra (which is most likely much safer)

 

[trialAcc]

What's the difference between the three trials? Do they upper the dose or something of the sort?

Phase 2 focuses more on safety then pure results, phase 3 is mainly results. The phase 2 tested 2 doses (0.25 and 0.5) and whichever preformed better would be the only tested arm in phase 3. I think they went with 0.5.

It's kind of odd to see a 6 month phase 3 trial, not really going to show us much more then the trial that just finished but its a requirement of the approval process. The health regulator might have specific questions about certain results from phase 2 (like serum buildup, potential rare adverse sides) that they will design the study to focus more on.

 

[Baldingtooyoung]

Very promising news indeed. Only personal concern is that while I trust they can follow deadlines, it still forces me to put off other potent treatments such as OM, RU or nuclear cycles. It would just be silly to hit the kitchen sink with something safe like KX just around the corner, but not sure how long this lousy NW2 has on Finas alone. This, along with their protac better be worth the wait cause it's the last hype train I'm boarding, and it's got till next year to take off.

We haven't seen one result or study of Kintor, we have on RU and OM, so this is a weird statement. You just assume a lot tbh.

 

[RolfLeeBuckler]

I almost feel like I might as well stick with RU for now, nice I can switch to pyra (which is most likely much safer)

But would you Go on Taking finasteride of pyra is available?

 

[fashy]

Nobody can answer this question right now dude. If pyri proves effective enough to hold all finasteride gains and maintains just as well with no side effects I'm sure 90% of people here will jump on it once it is available.
If it does not prove as effective then less people would make the switch and probably will just add it to their stack. It all depends on the results which we do not know yet.

 

[Chads don't bald]

So to be clear we won't really expect regrowth from pyri? It is mostly just a maintenance drug like finasteride?

Any growth agonists other than HMI on the horizon?

 

[John Difool]

So to be clear we won't really expect regrowth from pyri? It is mostly just a maintenance drug like finasteride?

Any growth agonists other than HMI on the horizon?

Some people have experienced regrowth on finasteride, some on minoxidil and on the big 3. It just depends how advanced your Norwood is. You must be an advanced case for routing on hmi like drugs. Don't put your hopes too high on AA or 5ARi then.

 

[trialAcc]

So to be clear we won't really expect regrowth from pyri? It is mostly just a maintenance drug like finasteride?

Any growth agonists other than HMI on the horizon?

The main measurement of efficacy of KX is mean new terminal hair count, so clearly they are expecting some degree of gains. It's just not going to be like regrowing a full area of long lost hair.

 

[Chads don't bald]

The main measurement of efficacy of KX is mean new terminal hair count, so clearly they are expecting some degree of gains. It's just not going to be like regrowing a full area of long lost hair.

Are the gains expected to be better than finasteride or is the difference only that there are no side effects? Because I've been on finasteride for half a year now and I don't think I've had any gains lol

 

[Chads don't bald]

Some people have experienced regrowth on finasteride, some on minoxidil and on the big 3. It just depends how advanced your Norwood is. You must be an advanced case for routing on hmi like drugs. Don't put your hopes too high on AA or 5ARi then.

Well I'm already on finasteride and it has maintained my hair but I haven't noticed any regrowth visually. I'd say I'm about a NW2 but rather than losing my hairline I'm just thinning all over which is arguable worse lol

I haven't tried any topical yet like minoxidil, mostly just waiting to see what I can get from finasteride. I just want that sweet NW0 tbh thats why I'm looking for something like HMI

 

[trialAcc]

Are the gains expected to be better than finasteride or is the difference only that there are no side effects? Because I've been on finasteride for half a year now and I don't think I've had any gains lol

Haven't seen the results from phase 2 so no one can answer that. Probably pretty similar but the difference is it's a different method of action, meaning it should stack on finasteride.

Most people don't get significant regrowth from finasteride or topical AA use, so expect similar. People have been using RU and other topical AAs for years and nothing groundbreaking has really come from it. If this is stronger then RU then I would expect better results but I think it would be very naïve to think there wont be sides for everyone with KX if it's a stronger AA then RU.

 

[Chads don't bald]

Hopefully stacking finasteride and KX gives us indefinite maintenance atleast

Would probably make hair transplant more viable too if you don't have to worry about losing any more hair in the future

 

[Dimitri001]

CB got the results finasteride gets in a year (in terms of TAHC) in 6 months (of course, we know what happens after that). Pyrilutamide, like CB, is an AR antagonist, but has a higher binding affinity (right?), so, theoretically, should only be better results.

Of course, the question is, what happens after 6 months.

 

[badnewsbearer]

CB got the results finasteride gets in a year (in terms of TAHC) in 6 months (of course, we know what happens after that). Pyrilutamide, like CB, is an AR antagonist, but has a higher binding affinity (right?), so, theoretically, should only be better results.

Of course, the question is, what happens after 6 months.

logic does notnapply though bc with CB results also degrwded fast while on finasteride improvement can be seen into the 2 yewr mark. also i think methologies and wordings in these papers are all over the place

when people say AA give no regrowth they mean areas where there is no hair, the majority, up to 70% of finasteride users see increase in terminal hair count(this is not regrowth as the hair would grow anyway at soke point, it is just that the growth phase has been lengthening due to less catagen promoting factors) however i consider this regrowth. i also consider regrowth when you have an increase in hair diameter, hair weight(thickening) as well as increased pigmentation which all make hair more rubust and they give more covering effect. (10 thick hairs is better than 15 thin hairs), pugmentation is also a big deal optically, many guys get very fine light hair, reversal of that is regroeth too and that is also experienced by the majority of finasteride users.

so to say imrpovements are not a thing is not true, just do not expect site where nit even vellus hairs grow to return to terminal hair, that is hard even for minoxidil responders

 

[BurningCoals]

How effective would pyrilutamide and finasteride stacked together be? One blocks the androgen receptor, the other the androgen itself. Sounds almost like a cure. Would be very useful for people who continue to lose hair on finasteride.

 

[trialAcc]

Those are just layers of protection.
In order to make the treatments works the best and basicly forever , you need AR degrader .
So UT-34+finasteride+Pyri will give better protection

Stop telling people they need something that doesn't exist. UT-34 is a research chemical that even the discord guys have not tested more then 3-4 days, not the holy grail of hairloss.

If you had a true and effective AR degrader, nothing else there would be needed.