My Zix Experience - How B6 And Zinc Have Saved My Hair

[Yagel]

I have bought the Zinc Arginine Study https://pubmed.ncbi.nlm.nih.gov/33878855/
and the results are pretty good. Apparently the Lotion consisting of Zinc-Gluconate and Arginine was as good as Finasteride after 6 months. However I think the dosages are very important and the study doesn't tell them.

They just say that the combination of 0,04% Zinc-Gluconate and Arginine caused a 75% Reduction in 5-Alpha Reductase in-vitro.

 

[fugged]

They also had an in vivo test right?

"We also performed an in-vivo study."

Did they say anything about that. Or could you post the most important parts of the study here please.

Edit: also very interesting they use zinc-gluconate, that's what is used in most zinc supplements. So basically confirms what most people already thought, no need for zinc sulfate heptahydrate. @worm

Pigeon how do you measure your arginine? I empty capsules of zinc and basically fill and empty three of those…

 

[fugged]

Hmm I got “pure” powder, weren’t you worried about the extra ingredients like corn starch etc? It may be nothing but over the days it would almost certainly start to change in solution I’d imagine.

 

[fugged]

Anything different to report? Probably too early

 

[Yagel]

They also had an in vivo test right?

"We also performed an in-vivo study."

Did they say anything about that. Or could you post the most important parts of the study here please.

Edit: also very interesting they use zinc-gluconate, that's what is used in most zinc supplements. So basically confirms what most people already thought, no need for zinc sulfate heptahydrate. @worm

Yes they did. They had 20 participants taking the Lotion with Zinc and Arginine and 20 with placebo.
Mean Hair Count improved by 52% after 6 months. These results are on the same level as finasteride.
They did not provide any photographs.

Unfortunately they did not tell the dosages of the ingredients.

It is also important to note, that some of the patients had telogen effluvium and not Androgenetic Alopecia.

 

[EndlessPossibilities]

Yes they did. They had 20 participants taking the Lotion with Zinc and Arginine and 20 with placebo.
Mean Hair Count improved by 52% after 6 months. These results are on the same level as finasteride.
They did not provide any photographs.

Unfortunately they did not tell the dosages of the ingredients.

It is also important to note, that some of the patients had telogen effluvium and not Androgenetic Alopecia.

No photos. What a bust. f*****g scientist. I cant beleive they database published them. The standards for getting published need to go up. Way way up.

 

[smoothbrain]

Edit: also very interesting they use zinc-gluconate, that's what is used in most zinc supplements. So basically confirms what most people already thought, no need for zinc sulfate heptahydrate. @worm

I read some study linked here that tested like 4 forms of zinc. It said they all worked, but zinc sulfate was less irritating than the others. I know many hair loss shampoos use zinc chloride, which is the more irritating form, but may not matter if your rinsing it off.

My recollection from something I read a while back is you could use way less. Have you searched the literature? There is a paper or two.

They used a .1% solution of melatonin In alcohol per 1ml each application. So my maths came up with 1mg per application.

 

[smoothbrain]

I feel like the arginine helps only because it's a vasodilator. So it basically just increases circulation. I think there's many things things that can do that like scalp massages or tipping your head in a downward slope. I use some herbal oil on the scalp that I massage and leave on for 20 min before shampooing.

 

[Yagel]

I feel like the arginine helps only because it's a vasodilator. So it basically just increases circulation. I think there's many things things that can do that like scalp massages or tipping your head in a downward slope. I use some herbal oil on the scalp that I massage and leave on for 20 min before shampooing.

According to the study, arginine is an inhibitor of 5-alpha-reductase aswell. But I think the problem is the dosage. Unfornately the study only provides the ingriedients of the Lotion and not the dosages.

I have tried to contact the author of the study, but I don't speak italian and the secretary of his Institute doesn't speak english.

 

[fugged]

Thanks for trying! Maybe we need a translated email. Unfortunately they probably want to keep it proprietary. Can we glean anything from the previous study that involved arginine? There was a second study correct?

 

[smoothbrain]

I just made my zix and I'm leaving it out for a night to dissolve more fully, but I'm considering leaving out the sediment when pouring the solution into bottles. I used a liquid zinc and the pure formulas b6 powder. I'm thinking the sediment is just fillers not actual b6.

The reason I think so is because I have used liquid b vitamins before and one 1oz bottle had 150mg b6 p5p total and I don't remember sediment.

Anyone ever buy pure p5p in powder form from bulk supplements or something and try to make zix? Did you still have sediment?

 

[Myco.1934]

According to the study, arginine is an inhibitor of 5-alpha-reductase aswell. But I think the problem is the dosage. Unfornately the study only provides the ingriedients of the Lotion and not the dosages.

I have tried to contact the author of the study, but I don't speak italian and the secretary of his Institute doesn't speak english.

Can you try to translate your message into italian with google translate?
Thank you for sharing the article with us.

 

[fugged]

Check this out, there’s something called zinc arginine

Zinc arginine, a 5 alpha-reductase inhibitor, reduces rat ventral prostate weight and DNA without affecting testicular function - PubMed

Zinc has been implicated in steroid endocrinology of the prostate gland; and 5 alpha-dihydrotestosterone (DHT) is believed to express androgenic responses in the prostate. To note the effect of neutralized zinc (zinc gluconate + arginine) on the prostate, 50 sexually mature rats, weighing 325...

pubmed.ncbi.nlm.nih.gov

 

[Myco.1934]

I wonder if arginine only works with zinc gluconate?

 

[fugged]

Doubtful I would imagine, if in fact arginine is efficacious it probably comes down to dosage and possibly vehicle for absorption.

 

[smoothbrain]

i applied zix for the first time last night. i had interrupted sleep waking quite a few times. my friend who also tried it had even worse sleep than me. he was awake most of the night.

perhaps its the b6 causing this?

 

[inmyhead]

I have bought the Zinc Arginine Study https://pubmed.ncbi.nlm.nih.gov/33878855/
and the results are pretty good. Apparently the Lotion consisting of Zinc-Gluconate and Arginine was as good as Finasteride after 6 months. However I think the dosages are very important and the study doesn't tell them.

They just say that the combination of 0,04% Zinc-Gluconate and Arginine caused a 75% Reduction in 5-Alpha Reductase in-vitro.

That study looks like scam. No dosage and no pictures. We have plenty of italians in forums. They should contact the authors.

 

[Yagel]

That study looks like scam. No dosage and no pictures. We have plenty of italians in forums. They should contact the authors.

But why should the make a scam about this? They are not selling any product.

 

[inmyhead]

But why should the make a scam about this? They are not selling any product.

Plenty of researchers are just trying to have some studies on their name. Or sometimes it's pressure from universities to publish something.

 

[fugged]

Maybe of interest

Complementary and Alternative Treatments for Alopecia: A Comprehensive Review

Abstract. The treatment of alopecia is limited by a lack of therapies that induce and sustain disease remission. Given the negative psychosocial impact of hair loss, patients that do not see significant hair restoration with conventional therapies often turn to complementary and alternative...

www.karger.com