Prolactin "minitherapy" with SMI-1 (novel protocol for lowering prolactin locally)

EndlessPossibilities

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I for one want this to be the holy grail. But you cant blame with the hundreds of lies and false promises and the failed expectations when it comes to hairloss. I also have seen the photos of the users using this substance and honestly they arent good enough for me to say without a doubt they work. I know extremely well how angles and Lighting and coincidental natural hair growth can go.

i remember i one time thought i had impeovement in my hairline. Took two great shots side by side. Shared it on reddit. Everyone upvoted. Now I realize it was just angles and lighting making it appear so.

lets give the experimenters 2 more months and hopefully we get some solid evidence it truly works
 

lostandfind

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Neither of the PRLR antagonists are even likely to cross the blood-brain barrier. Let's not turn this thread now from trolling to hypochondria. You're never going to find a safer treatment for any disease than inhibiting the prlr. If you're scared of blocking the prlr then maybe pharmacological intervention just isn't for you. I hear that Amazon is selling essential oils now.
Hi pegasus2. Greeting from the country where HopeMedicine is located. Do you mean there's a certain essential oil available on Amazon now that consists of SMI-6 or other types of PRLR antagonists?
 
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Gegen

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Hi pegasus2. Greeting from the country where HopeMedicine is located. Do you mean there's a certain essential oil available on Amazon now that consists of SMI-6 or other types of PRLR antagonists?
That's real !
 

DAVAT

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Hi pegasus2. Greeting from the country where HopeMedicine is located. Do you mean there's a certain essential oil available on Amazon now that consists of SMI-6 or other types of PRLR antagonists?
hang on, you're saying we can buy something similar to this on amazon??
 

Gegen

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Neither of the PRLR antagonists are even likely to cross the blood-brain barrier. Let's not turn this thread now from trolling to hypochondria. You're never going to find a safer treatment for any disease than inhibiting the prlr. If you're scared of blocking the prlr then maybe pharmacological intervention just isn't for you. I hear that Amazon is selling essential oils now.
you're saying we can buy something similar to this on amazon??
 

Johnson40

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Scottish has taken pictures for two months showing consistent progress. There is no such thing as coincidental natural hair growth of bald temples. If his pictures aren't enough for you to tell it's working the data reported by HMI should tell you that it will.

I think it was a mistake posting anything here and that we should keep our results to the discord itself. There is nothing to be gained for us by posting our experiments and research here, and frankly I don't see why we should help people who want to sit back and let us spoonfeed them the cure.

The discord has been closed off now, and I think we should only allow in those who've demonstrated that they can contribute.
Well, we have plenty of infos for now.
Just come by and reports stuff now and then, that's in your secret society best interest.

I've seen that this thread is being talked about on other website, it's not just HairLossTalk.com, bunch of forums around the world want this to work.
If you guys get good results, get a bit more clear on the price and how the group buy works you'll get way way more guy into it, there's a brazillions of potential test subject ( Myself included ).
 

MDL999

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Been on these forums for awhile. Given damn near everything a shot. I’ve continued to lose ground even on the most aggressive treatments (currently 150mg bicalutamide, 10mg oral minoxidil, 0.5mg dutasteride, and 2mg sublingual estradiol). I tend not to comment much because a very vocal group of people just come here to b**ch and distract from meaningful discussion. That being said having spent time in these forums over the past 3 years I’ve read a lot of Pegasus comments on a lot of different treatments and if he has optimism on this one so do I, because it’s really really hard for anyone who’s seen the rise and fall of 100 purported treatments to be optimistic.
Made my day i must say.
 

StayPositive

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Sorry, I was being sarcastic. There is currently no way to block prolactin at the hair follicle besides SMI, monocolonal antibodies, or CRISPR. SMI is obviously the only one that is an option right now. It can only be obtained by having a lab custom synthesize it. It's not readily available for purchase anywhere.
A few days ago you said you stopped all other treatments since getting on smi. Were you trolling or were you serious?
 

StayPositive

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Serious. I'm only using SMI and will be SMI only for the next couple months until I get an ERb agonist to go with it
So basically anti androgens/ 5ar inhibitors arent needed anymore? Wow we waited for this for so long..
 

Jacob Williams

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Does anyone have a theory or possible explanation for why this treatment would continue to show results so far past its cessation? That’s the most inexplainable part to me.
 

Jackshtbro

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Does anyone have a theory or possible explanation for why this treatment would continue to show results so far past its cessation? That’s the most inexplainable part to me.
I think it restores the hairs to back to their completely healthy states so it takes a few years before they start falling off again
 

DAVAT

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whats the timeframe for the next group buy, i.e when do you think we will have more photos of results?
 

DAVAT

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We should get more SMI in around 6 weeks. After that, people may report results or side effects even within two months. So most likely you will need to wait 3.5 months for news.

Ok cool. Very interested to see how it all pans out, good luck
 

lostandfind

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Sorry, I was being sarcastic. There is currently no way to block prolactin at the hair follicle besides SMI, monocolonal antibodies, or CRISPR. SMI is obviously the only one that is an option right now. It can only be obtained by having a lab custom synthesize it. It's not readily available for purchase anywhere.
Now I get it. Thank you anyway. BTW can any lab synthesize SMI-6 as long as it has the chemical composition and equipment?
 
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bicholouco

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Augustus and the others were right

I have hacked the discord and found this conversation

That last one with the flower emojis is the supplier and they are discussing their payments

Next time some guys on the internet claim they found the cure for hairloss think long and hard about what you're putting your money into. Hope you have learned your lesson
 
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Jackshtbro

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I have also hacked into the discord and found out that augustus10 is actually the seller!!!

As you can see he's posting under numerous nicknames to hide his identity but if you pay careful attention he uses the same phrases on this forum!!!
 

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