Prolactin "minitherapy" with SMI-1 (novel protocol for lowering prolactin locally)

[Ollie]

Hope Medicine raised 65 Million Dollar!!!‘ and i don’t know Where they put the money in. They didnt Start Trial they don’t have a website...

The investors will be kept in the loop more than the media. They have no benefit of putting on a show like replicel if they don’t need more money - that will come when marketing the drug.

 

[scientist_0005]

Yes we don’t Unterstand. Thats why we are in this Forum and ask questions

they are screening for very severe events here that would not permit any further studying of the drug in humans. things like heart failure, death, immediate allergic reactions etc. that is why studying men is not necessary because women and men on a grand scale are very similar genetically and the diffrrences are not going to produce these major adverse events. for more minor effects, the later studies are used for as well as efficacy of course. but with this one they know that if sou inject hmi in a human he wont die within a few weeks

 

[scientist_0005]

That doesn't typically get released, anyways it's only 2 years and they were only in the drug for 90 days so it wouldn't prove safety anyway. Even Phase III doesn't prove safety. Drugs have looked safe in all trials then come on the market and killed people

that is because safe drugs can kill people when you are very unlucky and have some sort of predisposition. generally the vast majority of drugs out of phase 3 are save. you also have to differentiate, for a cosmetic condition you may not accept a potential lethal side effect. but if the disease itself is so devastating you may very well accept such drugs and thus they shall be approved for those conditions even if they kill people in the trial, if the overall response is positive and decreases mortality for example.

people also abuse drugs and do not take them as intended.. so sure drugs kill people but its only half of the story.


generally phase 1 is there for a rewson and most major events would have occured there with tbis kind of drug.

i also think they would have occured in the primates as well

 

[trialAcc]

So Replicel was lot more professional then bayer regarding the data review of 5 Years phase 1 Trial

I guess Replicel is one of the most professional pharma companies on the planet, because again, no one does this.

 

[Will Be an Egg in 5 years]

So, it's over?

 

[fashy]

Over for what?! Nothing new has come to light to suggest anything is going wrong, can people just chill with their cynical sh*t until there's actually something to get pissed/happy about?