Reflex Hyperandrogenicity From Finasteride.

Ismael

New Member
My Regimen
Reaction score
0
Thanks a lot for your reply.
I decided to reduce the dose(from about 1.25 to 0.5), the shedding is getting better(but still have major shedding). I will see what is gonna happen. as you know, it is our last solution.
how long did it take (after you quite )till the acne disappeared and the shedding got back to normal ?
Yo dude i really hope u still around here and can help me, am gonne keep it short, Am on finasteride for 4 month hair shedding never stopt lossing 200+ a day lossing most likely hairs of my back and side look veru thin by now, i have reflex hyper 100% i stopt taking 1 mg took half a dose for 2 weeks now taking 0,25 for 2 weeks have you goth any tips for me what should i do ? Did your hair grow back? Did you stop taking it?
 

Mr SideEffect

New Member
My Regimen
Reaction score
1
Hey guys, so I'm at a crossroads with my hair loss and I could really use some advice from users who have taken Finasteride. I've been on finasteride for 8 months (1.25 mg/day generic) and during this time I have experienced accelerated hair loss across the entire top of my head, and my sides have gotten noticeably thinner. Additionally, I have experienced increased scalp oil, chronic mild testicular pain (has never gone away), increased ejaculatory volume, and decreased thickness of facial hair. I'm really worried that I might have reflex hypoandrogenicity, and I'm very close to just quitting finasteride altogether and relying on minoxidil/dermastamp/massage protocol for preventing further hairloss. Any suggestions? Is recovery from reflex hypoandrogenicity possible?
Hi there i have the same symptoms as you and amd slowly tappering off the drug i recommend you to do the if so you say l that your hair is much and being suffering from all these reflex symptoms,As am tappering off very slowy the itchy burnig scalp of mine disapeard, If you decide to quite the drug let me know so i can give u some tips,Remmember the quicker you quite the more lost hairs wil return back.
 

Mr SideEffect

New Member
My Regimen
Reaction score
1
The beard and body hair theories have been floated around this forum by different members so I'm guessing there must be something to it. Also, beard being affected by topical Fina is proof that topical goes systemic.
I have the same problem also suffering from reflex hyper and it does give you more facial its like you use steroids it takes your hair away but in return more facial hair,
Since I tried Cypro+Estradiol my hair loss has accelerated. Some guys are lucky, they can use every AA without side effects + lot of regrowth.

Don't try something stronger, you could regret it.
Hi am happy that you gain allot of hair back, How is your haif looking now? Am also suffering from reflex hyper and am slowly tappering off the drug after 4 month do you have anyy tips for me ?
 

Warrior123

New Member
My Regimen
Reaction score
0
Did you guys get "hyperandrogenicity" as soon as you started the treatment or after some time on the treatment because I don't understand when it usually occurs.. some say as soon as you get on the treatment and others few months or even years after the treatment.. I highly doubt that there is such a time range within that it can occur. @bluecyclone @inmyhead
 
Last edited:

bluecyclone

Senior Member
My Regimen
Reaction score
227
I don’t know if it was reflex or just a bad response to the meds. My doctor said reflex would have come with a huge acne breakout face and back.
 

Warrior123

New Member
My Regimen
Reaction score
0
Yeah, I really think that this concept of reflex hyperandrogenicity is still in the gray zone.. lot of completely different cases are thought to be RH not to say that the concept itself hasn't been studied (at least not on the hair/scalp) after so many people talking about it for years.. I also do not believe that receptors can upregulate themselves after less than a week on meds.. but why do some of us go through that "inititial shed" so soon? Is balding more than just sensitivity to DHT? Testosterone itself is also probably a cause of male pattern baldness for some of us.. or maybe we just expect too much from the drug that isn't even primarily used for hairloss (but for curing enlarged prostate). Hair regrowth and decline of hairloss are also just side effects of dutasteride and finasteride and not the primarily desired action of the drug.
 

mannyFJ

Established Member
My Regimen
Reaction score
81
All these mofos saying shed and thicker hair will come it is bullshit for me, My hair just got worst and worst on finasteride 14+ months on it and I thought it's chronic Telogen Effluvium since I have bulbs at end of hair. f*****g finasteride, i read about sides and i prepared myself but not for Telogen Effluvium or RH....that ain't listed as the sides. damn finasteride cuz miniaturization and 60% density lost from baseline
 
Last edited:

mannyFJ

Established Member
My Regimen
Reaction score
81
I don’t know if it was reflex or just a bad response to the meds. My doctor said reflex would have come with a huge acne breakout face and back.
right which my skin is clearer from finasteride but i now have dry skin, broken capillaries...things i can over look if the drug worked but i have accelerated hair loss so I don't think its reflex as I have no acne and hair that are falling have bulb at end which i believe is Telogen Effluvium
 

LifeIsSucks

Established Member
My Regimen
Reaction score
27
This doesnt make any sense, even tranny level drugs that destroy testosterone do not cause reflex hyperandrogenism let alone finasteride that seems like a candy compared to tranny drugs
 

mannyFJ

Established Member
My Regimen
Reaction score
81
This doesnt make any sense, even tranny level drugs that destroy testosterone do not cause reflex hyperandrogenism let alone finasteride that seems like a candy compared to tranny drugs
no finasteride can increase testosterone
 

Murkey Thumb

Experienced Member
My Regimen
Reaction score
688
I have had doubts for many years about the generalized 1mg dose for Finasteride and now conclude it is a nonsense. For some 1mg is way too much and will have a negative effect on a person's hormonal balance possibly leading to RH or other unwanted side effects. When I first started taking finasteride I used a 1.25mg dose which caused brain fog and sexual sides after repeated periods of stop/start(because nothing else worked) I settled on 0.25mg which works fine for me and is so far side free. My point being we are all different and if you are going to experiment with finasteride start with a low dose not the recommended dose.
 

Manochoice

Experienced Member
My Regimen
Reaction score
286
I have had doubts for many years about the generalized 1mg dose for Finasteride and now conclude it is a nonsense. For some 1mg is way too much and will have a negative effect on a person's hormonal balance possibly leading to RH or other unwanted side effects. When I first started taking finasteride I used a 1.25mg dose which caused brain fog and sexual sides after repeated periods of stop/start(because nothing else worked) I settled on 0.25mg which works fine for me and is so far side free. My point being we are all different and if you are going to experiment with finasteride start with a low dose not the recommended dose.
How long have you been on .25?
 

kungfukenny

Established Member
My Regimen
Reaction score
123
I have had doubts for many years about the generalized 1mg dose for Finasteride and now conclude it is a nonsense. For some 1mg is way too much and will have a negative effect on a person's hormonal balance possibly leading to RH or other unwanted side effects. When I first started taking finasteride I used a 1.25mg dose which caused brain fog and sexual sides after repeated periods of stop/start(because nothing else worked) I settled on 0.25mg which works fine for me and is so far side free. My point being we are all different and if you are going to experiment with finasteride start with a low dose not the recommended dose.
I wish I had done that. I started on 1mg and it’s gave me RH
 

baba_yaga

Experienced Member
My Regimen
Reaction score
647
Yeah, I really think that this concept of reflex hyperandrogenicity is still in the gray zone.. lot of completely different cases are thought to be RH not to say that the concept itself hasn't been studied (at least not on the hair/scalp) after so many people talking about it for years.. I also do not believe that receptors can upregulate themselves after less than a week on meds.. but why do some of us go through that "inititial shed" so soon? Is balding more than just sensitivity to DHT? Testosterone itself is also probably a cause of male pattern baldness for some of us.. or maybe we just expect too much from the drug that isn't even primarily used for hairloss (but for curing enlarged prostate). Hair regrowth and decline of hairloss are also just side effects of dutasteride and finasteride and not the primarily desired action of the drug.
Receptors undergo upregulation during the first week of treatment. Their number go up a little bit then comes down. The receptors quantity virtually stays the same. However, sensitivity could be the cause of RH.

RH is the only reason I am not on finasteride.
 

Paulhenry

New Member
My Regimen
Reaction score
3
I had a similar story with topical dutasteride.

I had a really slow hairloss int he vertex area for two years and tried a minoxidil solution with horse placenta, oxytocin and 0.1% dutasteride.

Ive been using it only two times with less than the recommanded dose but had to stop du to chest pain.
Less than one month after I had loss 75% of my hair were I applied the product and developped seborrheic dermatitis.
I completely shaved my head and to apply prednisolone to fight against inflammation but hair are not growing back.

I am not sure it's RH but it was so fast I cannot believe it is something else.

Here are two pictures. Two months intervall but the whole thing mainly occured in less than 20 days.
 

Attachments

  • 0_IMG_20200909_102312.jpg
    0_IMG_20200909_102312.jpg
    119.1 KB · Views: 210
  • IMG_20201112_110237.jpg
    IMG_20201112_110237.jpg
    125.3 KB · Views: 222
Last edited:

trialAcc

Senior Member
My Regimen
Reaction score
1,531
I mean, this isn't a 70% loss in hair, the swirl is the same and you thinned out a bit above it but you can't even see it in the first picture you showed. I find it almost impossible to believe you could do this from two doses.
 

jamesbooker1975

Senior Member
My Regimen
Reaction score
1,027
Hello everyone.
so I have been on 1mg/daily of finasteride for about two months.
about two days after I started taking it and until know, I have been experiencing Intense shedding. I shed everyday about 400 of dark, and thick hair. Also, my skin got worse and I had some acnes. I didn't have any single sexual side effect, sometimes I even feel that my sex drive is even better. It seems that I am having reflex hyperandrogenicity from finasteride.
My question now, should I just stop taking it, or it is better to wait more ?
anyone has experienced this side effects?

P.s: About a year ago, I tried Minoxidil for about 5 months and I experienced also an
Intense shedding, so I decided to drop it off. I don't know if there is a connection.
What about a blood test ?
 

trialAcc

Senior Member
My Regimen
Reaction score
1,531
I can attest to finasteride causing reflex hyperandrogenicity in some individuals. I had a thick head of hair with very slight recession (in hindsight it was most likely just a mature hairline forming); after a month or so of taking 1mg of finasteride I was losing tons and tons of hair daily, got horrendous acne (never had this in my teens) and build up a layer of sebum on my scalp that was almost impossible to get rid off. I stupidly continued using it for about a year, hoping it would stabilize eventually. But things only got worse. The sebum and acne went away after quitting finasteride and the shedding lessened but never stopped. I never recovered the hairs lost and it definitely put my male pattern baldness in hyperdrive. It fucked up my life just when it was about to start.
I honestly still don't think this is a real thing, and I've been trying my hardest to find evidence of it in real medical literature for any similar drug. It just seems like the bodies reaction to the increase in testosterone cause by the finasteride. Some people are more sensitive to fluctuations in T then others and it definitely increases oil/sebum which probably captures more DHT in the follicle and can speed up shedding or flare up sebderm/psoriasis for a certain period. Did you ever bother to get your scalp looked at or biopsied during this time?

I had this when I first started finasteride for 4-5 months years ago, yet my scalp eventually got less oily and my loss stabilized. Now after a break I have it again, but I just have less hair this time and the sheds have me more paranoid.
 
Top