Shiseido has been collaborating with two University Hospitals on a clinical study on the establishment of “hair regenerative medicine technology” in Japan. This technology is the world’s leading hair regeneration/patented technology. After culturing the dermal sheath cup cells (which are considered to be the source of hair dermal papilla cells that play an important role in the growth of hair) isolated from the patient concerned about pattern baldness and thinning hair, they are implanted (injected) into the balding scalp skin to rejuvenate the damaged hair follicles as well as promote the growth of healthy hair. Regenerative medicine refers to the treatment method, in which tissues/cells of human origin are implanted into the patients who cannot be treated by existing treatment methods, and curing by self-renewing capability is expected. There are two types of implantations: “autologous cell implantation” in which the cells of the relevant patient are utilized and “allogeneic cell implantation” in which the cells of other people are utilized. The technology Shiseido is working on is the autologous cell implantation technology, which is considered to have fewer side effects of immune rejection, etc. and higher safety level than allogeneic cell implantation. With regard to the pattern baldness and thinning hair, presently hair growth/regrowth agent for external application and oral treatment agent with androgen suppression effect are put into practice. However, there are some issues including the facts that limited topical dosage exists for females and oral treatment agents are not applicable to female patients. The introduction of this technology is expected to have less physical burden due to surgical procedures, reduce rejection reaction risks after cell implantation, and be applicable to all patients regardless of gender. Therefore, the concerned persons look forward to the technology being widely utilized as soon as possible.
Tokyo Medical University starts clinical study on the establishment of hair regenerative medicine technology
https://corp.shiseido.com/en/rd/development/newresearch.html