RU 250mg per day is actually working

[Isneezedsohard]

I need a better vehicle because the ORM is just way to potent for me even at a 0.0025mg dose. It just keeps going systemic and I'm getting tired of having to keep on diluting it. By better vehicle, I mean a vehicle that is much less penetrating. I either need to reduce the amount of alcohol or PG I use in my vehicle, or both.

If there was a vehicle that kept ORM localized and didn't allow systemic absorption, that would be the cure for many guys because ORM is affordable and safe if gone systemic. The only problem is that it causes gyno when gone systemic. It blows my mind how the best minds in science can't come up with (or aren't trying to) an antiandrogen that will substantially reduce hair loss

I thot u said it was expensive...

 

[AndrewBarnes]

I thot u said it was expensive...

That was before I tested it on myself and found out how little of the product you actually need to use. I bought mine for $350 for 1 gram but I don't even need 1 gram. 10mg would last you a very long time. I can use minuscule amount and see results but YMMV

ORM is the best anti-androgen for hair loss available right now (if I'm wrong, please let me know of other AA that are better). ORM is not expensive, safe if gone systemic, doesn't cause brain fog because it doesn't cross the blood-brain barrier, doesn't cause libido issues, won't cause heart palpitations like RU, is super potent, and has a much shorter half life than other anti androgens.

 

[Isneezedsohard]

That was before I tested it on myself and found out how little of the product you actually need to use. I bought mine for $350 for 1 gram but I don't even need 1 gram. 10mg would last you a very long time. I can use minuscule amount and see results but YMMV

ORM is the best anti-androgen for hair loss available right now (if I'm wrong, please let me know of other AA that are better). ORM is not expensive, safe if gone systemic, doesn't cause brain fog because it doesn't cross the blood-brain barrier, doesn't cause libido issues, won't cause heart palpitations like RU, is super potent, and has a much shorter half life than other anti androgens.

Crazy! I’ve literally never heard of it b4

 

[AndrewBarnes]

Crazy! I’ve literally never heard of it b4

It's not common on here but I got the idea of using it from here. This stuff works way better than anything I've ever tried. I don't know why more people don't use it. Probably the initial price that scares them or they're happy with the results they're getting with whatever they're using.

 

[AndrewBarnes]

https://www.hairlosstalk.com/interact/threads/darolutamide-odm-201-a-better-topical-than-enzalutamide.105402/page-24

IdealForehead mentions in this thread that he was using 300mg of RU (similar to me) and then switched over to Daro and daro stopped all his hairloss. The only difference is that IdealForhead can tolerate 5mg of Daro daily, which is an insane amount for me. His daro is either not that pure or our bodies just handle daro differently.

 

[AndrewBarnes]

After some research, PG is used in vehicle formulas because it doesn't evaporate as quickly as water/ethanol and allows the product you're using to sit on the skin for longer, thus increasing penetration. I'm going to create a batch of ORM with no PG in order to prevent the ORM from going systemic. I will only use ethanol and water as a vehicle. Not sure what concentration of water/ethanol to use yet but will experiment.

 

[Pls_NW-1]

Update: On Wednesday, I lost 20 hairs in the shower and today (Friday) I lost only 13. I've had a hair catcher for around a year now and 13 hairs is the lowest amount I ever lost. ORM is the real deal. 500mg of RU didn't even give me the same results as 0.0025mg ORM (dose I'm using now).

Crazy, I know people complaining about dry eyes and dry skin from the usage of daro, but you do good, right?

 

[AndrewBarnes]

Crazy, I know people complaining about dry eyes and dry skin from the usage of daro, but you do good, right?

I've never had those symptoms. The only symptoms I experienced is increased water retention and a puffy right nipple, both of which are associated with the ORM going systemic, blocking test/DHT, and causing me to have a estrogen dominant hormone profile. I'm seeing amazing results in terms of how much hair I'm losing but I need to find a vehicle that provides less absorption of the ORM, because it's just wayyy too potent for me. I've only had similar sides from 500mg RU daily, which goes to show you how much more powerful ORM is compared to RU. The thing is, RU causes heart palpitations/heart problems because it's a non-selective antiandrogen. ORM is much safer.

 

[telogen]

I've never had those symptoms. The only symptoms I experienced is increased water retention and a puffy right nipple, both of which are associated with the ORM going systemic, blocking test/DHT, and causing me to have a estrogen dominant hormone profile. I'm seeing amazing results in terms of how much hair I'm losing but I need to find a vehicle that provides less absorption of the ORM, because it's just wayyy too potent for me. I've only had similar sides from 500mg RU daily, which goes to show you how much more powerful ORM is compared to RU. The thing is, RU causes heart palpitations/heart problems because it's a non-selective antiandrogen. ORM is much safer.

Are you using any other hairloss treatments apart from ORM? And how do you even manage to mix tiny amounts like 0.0025mg? My scale is having problems showing correct weight for anything under 10 mg.

Update: On Wednesday, I lost 20 hairs in the shower and today (Friday) I lost only 13. I've had a hair catcher for around a year now and 13 hairs is the lowest amount I ever lost. ORM is the real deal. 500mg of RU didn't even give me the same results as 0.0025mg ORM (dose I'm using now).

But ORM is giving you more sides too?

 

[Pls_NW-1]

Are you using any other hairloss treatments apart from ORM? And how do you even manage to mix tiny amounts like 0.0025mg? My scale is having problems showing correct weight for anything under 10 mg.



But ORM is giving you more sides too?

ORM is the best thing you can actually do for hair loss, if you can manage to make a proper batch for it too.

And thats where our opinions match together; HOW DOES HE MIX THOSE MICRO-DOSAGES TOGETHER!?

 

[Norwoody]

Maybe try a carrier that is not as efficacious. And/or mix with other stuff that has a larger particle size.

 

[AndrewBarnes]

Maybe try a carrier that is not as efficacious. And/or mix with other stuff that has a larger particle size.

I mixed a batch last night only using a tiny bit of alcohol and water. No PG.
The dosage of ORM is 0.0008333mg/mL. Each mL = 0.3125% alcohol, 99.69% water.
If the ORM doesn't go systemic, I'll slowly add in PG or increase the dose.

The way I'm able to create such small doses is by measuring approximately 1-2mg of ORM (I have a 0.001g scale, mixing it with alcohol, and then diluting it. For example, if I make a batch with 1mg ORM / mL, I would take a 0.25 mL of it and put it in another container giving me 0.25mg ORM per .25mL, if I needed a 0.025mg dose per 1 mL I would add 9.75mL of a vehicle to it (0.25mg / 0.025mg = 10 x mL = 10mL)

 

[Pls_NW-1]

I mixed a batch last night only using a tiny bit of alcohol and water. No PG.
The dosage of ORM is 0.0008333mg/mL. Each mL = 0.3125% alcohol, 99.69% water.
If the ORM doesn't go systemic, I'll slowly add in PG or increase the dose.

The way I'm able to create such small doses is by measuring approximately 1-2mg of ORM (I have a 0.001g scale, mixing it with alcohol, and then diluting it. For example, if I make a batch with 1mg ORM / mL, I would take a 0.25 mL of it and put it in another container giving me 0.25mg ORM per .25mL, if I needed a 0.025mg dose I would add 9.75mL of a vehicle to it (0.25mg / 0.025mg = 10 x mL = 10mL)

clever girl

 

[AndrewBarnes]

Are you using any other hairloss treatments apart from ORM? And how do you even manage to mix tiny amounts like 0.0025mg? My scale is having problems showing correct weight for anything under 10 mg.



But ORM is giving you more sides too?

RU gave me more sides than ORM. RU gave me headaches in the beginning, gave me a tightness in my neck, heart palpitations, water retention, and made my gyno flare up. ORM increases my water retention and makes my gyno flare up.

 

[AndrewBarnes]

Are you using any other hairloss treatments apart from ORM? And how do you even manage to mix tiny amounts like 0.0025mg? My scale is having problems showing correct weight for anything under 10 mg.



But ORM is giving you more sides too?

Right now I'm only using ORM and 1.25mg finasteride (proscar tablet cut into fourths)

 

[1919]

Wow never heard of ORM15341. Is there anyone else using this chem with success? Seems promising.. Keep it up!

 

[Pls_NW-1]

Wow never heard of ORM15341. Is there anyone else using this chem with success? Seems promising.. Keep it up!

@IdealForehead introduced it back then to the forum.

Like all other people... they cure themselves and leave the forum, cuz new hair = new life lol

 

[Pls_NW-1]

i traced it back to this post....

google: baldtruthtaIk i think i've hacked it

i do wonder if there is a missing component - @AndrewBarnes is on finasteride and has done RU for some time, ideal did RU for sometime and ran CPA immediately prior to ODM without PCT - would be curious what is going on that makes ODM/ORM work for some...

Why shouldn't ODM/ORM work for some? Has it to pass anything to become active or what am I missing?

 

[1919]

Why shouldn't ODM/ORM work for some? Has it to pass anything to become active or what am I missing?

I found this thread on ODM:

https://www.hairlosstalk.com/interact/threads/darolutamide-odm-201-a-better-topical-than-enzalutamide.105402/page-78

Apparently Ideal was the only one with results from daro by 2019 according to user hemingway. Not sure how reliable this is but if a cure-all treatment existed, we would all be using it. Ill be waiting for Andrew's updates, lets hope they work in his favor.

 

[Pls_NW-1]

I found this thread on ODM:

https://www.hairlosstalk.com/interact/threads/darolutamide-odm-201-a-better-topical-than-enzalutamide.105402/page-78

Apparently Ideal was the only one with results from daro by 2019 according to user hemingway. Not sure how reliable this is but if a cure-all treatment existed, we would all be using it. Ill be waiting for Andrew's updates, lets hope they work in his favor.

Its always problematic to make a good topical work because of the absorption ngl. Thats why I refuse topicals.