RU Side Effects & Androgen Levels: User Feedback Required

[bags]

Curious to know; how many guys using RU are also on TRT or have naturally High Free Test / DHT levels??

Im asking because im wondering if having low Free T or DHT could increase side effects of RU due to an increased ratio of RU to Free T/DHT in the system around heart chest etc....

That would explain why some ppl get horrible sides from RU because maybe they dont have enough Free Androgens competeing for receptors in systemic areas etc...

If thats the case Im curious to know: Those of you who have had sides, were you on TRT? Do you know what your Free T/DHT levels are when you took RU?

And of those of you who had no sides; Do you know what youre Free Androgen levels are / were as well?

Maybe cycling gear with RU would make it more safe due to competeing androgens... we only need it on the scalp anyway.... JM2C

 

[el_duterino]

Dude, RU is dead.
Why are people even discussing this drug in 2020 ? get on CB aka Clascoterone, same mode of action without the side effects and unknown other potential effects.

 

[sonictemples]

Dude, RU is dead.
Why are people even discussing this drug in 2020 ? get on CB aka Clascoterone, same mode of action without the side effects and unknown other potential effects.

Wish it was as affordable as RU is

 

[el_duterino]

Dude, I use 50mg a day, I payed 60 USD per gram, that cost me 3 USD a day.
Are you telling us you cannot afford 3 USD a day for a top class FDA approved, hair maintenance drug with a known safety profile ?

 

[sonictemples]

I don't make money in USD and my country's currency and US's currency has a big gap between them unfortunately

 

[Norwoody]

Dude, I use 50mg a day, I payed 60 USD per gram, that cost me 3 USD a day.
Are you telling us you cannot afford 3 USD a day for a top class FDA approved, hair maintenance drug with a known safety profile ?

I'm considering it. Have you had lab work done to see if it affected your testosterone? Thanks

 

[Norwoody]

@el_duterino , What percent solutions of CB have you used?

 

[jazz1]

Dude, I use 50mg a day, I payed 60 USD per gram, that cost me 3 USD a day.
Are you telling us you cannot afford 3 USD a day for a top class FDA approved, hair maintenance drug with a known safety profile ?

I see Anagenic Inc sell CB-03-01, so you could in theory use KB solution or the ethanol mixture? What’s the best lowest dosage to start?

They also selling other powders I never heard about......

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anageninc.com

 

[bags]

Dude, RU is dead.
Why are people even discussing this drug in 2020 ? get on CB aka Clascoterone, same mode of action without the side effects and unknown other potential effects.

LMFAO RU is dead?

How? It literally has the same AR binding affinity and strength as Testosterone. Less than DHT but equal to Test. CB has 1/50th the binding afinity and in all clinical studies has significantly reduced efficacy after just 7 months lol.

Good luck holding on to your hair with CB. And for those who think it would have no systemic sides in high enough concentration if got into the blood stream... did you ever wonder why? Again; BINDING AFINITY... its weaker than using Saw Palmetto. Fact.

 

[randolf_faust]

Dude, RU is dead.
Why are people even discussing this drug in 2020 ? get on CB aka Clascoterone, same mode of action without the side effects and unknown other potential effects.

where can you buy this though?

 

[randolf_faust]

LMFAO RU is dead?

How? It literally has the same AR binding affinity and strength as Testosterone. Less than DHT but equal to Test. CB has 1/50th the binding afinity and in all clinical studies has significantly reduced efficacy after just 7 months lol.

Good luck holding on to your hair with CB. And for those who think it would have no systemic sides in high enough concentration if got into the blood stream... did you ever wonder why? Again; BINDING AFINITY... its weaker than using Saw Palmetto. Fact.

ah damn people are so worried about possible side effects that they miss the whole purpose from anti hairloss medication to beginn with - to stop hairloss. guess cb is no alternative then

 

[randolf_faust]

LMFAO RU is dead?

How? It literally has the same AR binding affinity and strength as Testosterone. Less than DHT but equal to Test. CB has 1/50th the binding afinity and in all clinical studies has significantly reduced efficacy after just 7 months lol.

Good luck holding on to your hair with CB. And for those who think it would have no systemic sides in high enough concentration if got into the blood stream... did you ever wonder why? Again; BINDING AFINITY... its weaker than using Saw Palmetto. Fact.

how can it stop hairloss when dht has a stronger binding affinity? just by stoping testosterone (which apparently can itself also can cause hairloss)?

 

[Topher]

how can it stop hairloss when dht has a stronger binding affinity? just by stoping testosterone (which apparently can itself also can cause hairloss)?

Dutasteride, finasteride ?

 

[el_duterino]

How can CB stop hairloss, has already been proven by studies, after a year all the participants even the ones using the lowest concentrations stayed above baseline.

Unlike RU, it is quickly metabolized in skin and has very little side effects. I know the RU side effects, I was on it for 9 years. I use CB, it works fine. I don't need finasteride or dutasteride, it can replace those drugs.

As for Binding affinity - none of the synthetic anti androgen can compete with DHT on binding affinity, even the strongest prostate cancer drugs have only a fraction of the affinity of DHT. They work because the molecules are 1000 times more abundant than DHT.

 

[Topher]

How can CB stop hairloss, has already been proven by studies, after a year all the participants even the ones using the lowest concentrations stayed above baseline.

Unlike RU, it is quickly metabolized in skin and has very little side effects. I know the RU side effects, I was on it for 9 years. I use CB, it works fine. I don't need finasteride or dutasteride, it can replace those drugs.

As for Binding affinity - none of the synthetic anti androgen can compete with DHT on binding affinity, even the strongest prostate cancer drugs have only a fraction of the affinity of DHT. They work because the molecules are 1000 times more abundant than DHT.

Just stop hairloss or could it reverse hair loss do you think?

 

[el_duterino]

Anti androgen have been prescribed to older men since the mid-1970's , flutamide which is quite powerful and was used orally at 250mg a day was one the first, so that's very effective to combat hair loss as the drug gets effectively delivered to each hair follicle via blood stream, and at high dosages.

We do not have reports of men growing back lost hair on these type of drugs, and we are talking decades of usage, this is also line with the Norwood experiments from the 1940's..

IF you have lost coverage issues, aka a big forehead, your best bet is to go for a FUE transplant, techniques have improved a lot these last years and that's what I had done. In fact I have a nicer hairline than what I had at 18, with a very close to natural density.

 

[Selb]

Anti androgen have been prescribed to older men since the mid-1970's , flutamide which is quite powerful and was used orally at 250mg a day was one the first, so that's very effective to combat hair loss as the drug gets delivered to each hair follicle via blood stream, and at high dosages.

We do not have reports of men growing back lost hair on these type of drugs, and we are talking decades of usage, this is also line with the Norwood experiments from the 1940's..

IF you have lost coverage issues, aka a big forehead, your best bet is to go for a FUE transplant, techniques have improved a lot these last years and that's what I had done. In fact I have a nicer hairline than what I had at 18, with a very close to natural density.

So what’s the best growth inducer in your opinion? If you’re maintaining with finasteride or cb, but want density back

 

[jackthesmack]

Dude, RU is dead.
Why are people even discussing this drug in 2020 ? get on CB aka Clascoterone, same mode of action without the side effects and unknown other potential effects.

The issue is testing it though, ive emailed like 40 different labs (live in the Uk) with no success. I have cb from kane just lying on my table, if u can point me to where i can get its purity tested then I will pray to my God for you to have hair for life dude

 

[jackthesmack]

LMFAO RU is dead?

How? It literally has the same AR binding affinity and strength as Testosterone. Less than DHT but equal to Test. CB has 1/50th the binding afinity and in all clinical studies has significantly reduced efficacy after just 7 months lol.

Good luck holding on to your hair with CB. And for those who think it would have no systemic sides in high enough concentration if got into the blood stream... did you ever wonder why? Again; BINDING AFINITY... its weaker than using Saw Palmetto. Fact.

CB is dose dependent whereas RU is not, so the binding affinity point is moot

 

[nick123]

Dude, I use 50mg a day, I payed 60 USD per gram, that cost me 3 USD a day.
Are you telling us you cannot afford 3 USD a day for a top class FDA approved, hair maintenance drug with a known safety profile ?

What percentage would 50mg a day be?
Also whos your source for CB?