s5 cream??

ali777

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m0rpheus said:
Lets get this straight. I always see spironolactone topical topics and everyone gets all excited. I too get excited about the idea.

Who has actually had results in topical spironolactone? Because I am yet to see many/if any threads after hours of research on numerous forums which are singing the praises of topical spironolactone working. I do sometimes read some positive results but usually they have started minoxidil/propecia etc at the same time.


Also i quote from the website linked above.

Spironolactones have been used for hair loss for decades. Early in my career, I had asked well respected dermatologists about their experience with spironolactones and the results for the treatment of hair loss. The consistent story I got from them was that they were not efficacious and patients who used them, with or without other injectable medications used in the head, had no significant demonstrated benefit. With that knowledge, the written material that you’ve sent me seems to fall flat, missing some elements of science in the practical world of clinical medicine.

I'm in the same dilemma. I want to try it, but I can't make up my mind about it. I'm falling short of committing myself. If I see one positive post, I will order it.

I applied some generic cream on my scalp just to see how messy it gets, I can live with applying cream on my scalp but I don't want to lie to myself and try something that may not work. I mean I don't want to get my hopes high for something that isn't proven to work.
 

Rework24

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I am using it in conjunction with minoxidil. Will post my 3 month results at the end of May
 

Whoop

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Due to sides I can't handle finasteride, so I'm very interested in this product.

Will a regime of topical spironolactone 5%/Minoxidil 5%/Nizoral maintain my hair? Or do I have to add another thing?
 

striker9

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So if no one appear to have results with photos, etc.


It means spironolactone don't work right?
 

Petchsky

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striker9 said:
So if no one appear to have results with photos, etc.


It means spironolactone don't work right?

No, it either means there is no one on the board that uses spironolactone exclusively/with photos, or that spironolactone gives no regrowth and is maintenance only, which is what I believe, also why there's not loads of people on the net heralding it as a great discovery.
 

Fundi

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Petchsky said:
striker9 said:
So if no one appear to have results with photos, etc.


It means spironolactone don't work right?

No, it either means there is no one on the board that uses spironolactone exclusively/with photos, or that spironolactone gives no regrowth and is maintenance only, which is what I believe, also why there's not loads of people on the net heralding it as a great discovery.

I think I agree with this. spironolactone is for maintenance - Or it will slow your hairloss down.

So those who use it exclusively will not see new growth, or will carry on losing hair (At a rate slower than what they would have done without it) - Both decent returns in my opinion, but therefore will not be raving about it.
 

Rework24

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Why would you not see re-growth if spironolactone was preventing the dht binding to the androgen receptor?

Is it a case that spironolactone is not a powerful enough anti androgen?

I'm just at the end of first month of using 5% cream but in conjunction with nanominox and after shedding loads of hair at my temples I am starting to see some good early indications of potential re-growth, my crown has not shown any changes so far.
 

striker9

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Hi agree with rework.

Because if you are retarding the hair loss with finasteride, and you even have another anti-dht, the follicle should be even more binded and have space to grow normally!

This means flutamide don't work, not even spironolactone.

if we don't have photos or aren't working for anyone.....

and isn't spectral dnc better than nanomix? we are talking about anti-dht, forget hair stimulants
 

Bryan

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Rework24 said:
Why would you not see re-growth if spironolactone was preventing the dht binding to the androgen receptor?

Is it a case that spironolactone is not a powerful enough anti androgen?

I think it's true in general that spironolactone isn't a particularly powerful antiandrogen when applied topically, but that's not really the main take-home message here. I think it's really important for you to understand that humans just don't have that much of a general propensity for regrowth of scalp hair, even under the most extreme conditions of removing androgens. Even castration + powerful systemic antiandrogens like flutamide won't cause THAT much regrowth, unless you have lots of recent loss. Androgenetic alopecia in humans is mostly a one-way street: removing androgenic stimulation would be a good strategy for stopping further hair loss, but you can't expect a lot of regrowth of hair that's been gone for a long time.
 

Rework24

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well thats helped me to look on the bright side of things :sobbing:

just out of curiosity what if anything do you take to combat hair loss?
 

striker9

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So we only have rogaine and propecia(or avodart) there aren't any solution outthere?

I see spironolactone don't work..
 

Whoop

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Striker, you are making conclusions way too quick. Maintaining is already a very big plus.
 

striker9

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Yeah maybe your are right.

I still have much follicles even they are very thing. I just want to make the right decision.

So what people really recommend that works has an topical anti-dht without sides?
 

Hectic_Jam

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I think i may give this topical spironolactone a try, i still have a good decent amount of hair on my head and if this stuff at least helps slow it down i'm up for it.
 

striker9

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My dermatologist said spironolactone is too weak.

So what people are you using has a anti-dht topical?
 

kennyk

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I have been using s5 for about 4 months and i have noticed darker thicker hair in a 1/4 of an inch spot where it was once thin, barely noticeable hair. Maybe my imagination but i hope not.
 
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