Sandalore - Chemical Used In Perfumes To Mimic Sandalwood Triggers Growth?

[NotInmywatch]

The reason you guys are having success with Sandalore and it works (we'll just wait and see how much) is this:

Dihydrotestosterone inhibits hair growth in mice by inhibiting insulin-like growth factor-I production in dermal papillae.

TGF-β1 secretion is increased by androgen treatment in DP-6

And the way that Sandalore helps:

"This analysis revealed a significant decrease in TGF-β2 (Supplementary Fig. 3a) and a significant increase of IGF-1 (Fig. 1d) protein expression in the proximal ORS after long-term Sandalore® treatment"

this case illustrates the extreme importance of delivery vehicle and active agent permeability on human skin.
n-acetylcysteine (NALC), mentioned in the 2nd article, has already been described as a good inhibitor a ROS-mediated, androgen-induced destruction of the hair follicle:

Prostaglandin D2 Uses Components of ROS Signaling to Enhance Testosterone Production in Keratinocytes.

However, there is not one single study using NALC on Androgenetic Alopecia patients, probably because of poor skin delivery. Go Sandalore go !

 

[Renegade000]

Hope we will not all be getting cancer down the line.

Do we have any reason at all to think there may be a cancer risk?

 

[Jamesdunn]

Do we have any reason at all to think there may be a cancer risk?

The igf that would probably have more chance giving us cancer is in our diets. I very much doubt 1% concentration of sandalore would cause anything!

 

[whatevr]

The igf that would probably have more chance giving us cancer is in our diets. I very much doubt 1% concentration of sandalore would cause anything!

Let's see some more pictures man!

 

[Jamesdunn]

Update of crown.

 

[Jamesdunn]

Regrowth?

 

[INT]

Do not see much difference in this one... Is the right one after?

 

[Jamesdunn]

Do not see much difference in this one... Is the right one after?

Yes and I disagree

 

[Vinc2097]

Hey guys ! what is the best mix people have came up with for 60 ml.

(all ingredients, ml, etc)

 

[Vinc2097]

Or, just add the Sandalore to the Minoxidil mixture containing the pg. Or would the chemical structure of the Sandalore be broken down by such mixture? Can't think of any ionic reactions possible.

how can people apply 99 % alcohol topical on their scalp without feeling burnt. every time i have a topical with more than 15 % alcohol i can't tolerate it...

 

[Rock12]

Update of crown.

It would be helpful if you could label your pics with the time they were taken.

 

[turfboy]

I posted some before and after photos about a week ago. I will upload more today, but wanted to make a few comments/observations. I have been on the Sandalore for about 6-7 weeks or so. One poster asked about shedding... since my hair is so short (and there isn't much of it) sheds are difficult to determine, but shortly after my last posting, I feel that I went through a shed period. I believe I am just now coming out of it. Also, about 5-6 days ago changed my mixture and application method (more about that in the next post).

 

[inmyhead]

Lol a bit complicated for me still...

What matters most though: Will sandalore cause the same side effects as fina or not?

Is this trolling or are you really this dumb?

 

[turfboy]

Here is a side by side photo - left side photo taken Nov 24, right side photo taken Dec 29 (ovbiously the hair is longer on Dec 29).

 

[turfboy]

Nearly all the photos I take are directly over the top (bird's eye view). Obviously, this is not an angle I or anyone else really sees. For perspective, I'm attaching the frontal view which is what I see when looking in the mirror.

 

[whatevr]

Lol a bit complicated for me still...

What matters most though: Will sandalore cause the same side effects as fina or not?

It will not. It doesn't do anything hormonal as far as we're aware, it simply modulates some cytokines and growth factors inside the follicle itself. Whether it has any unique sides of its own we don't know yet, but so far it seems pretty safe.

 

[INT]

No need to quote me if you aren't answering the question c***.

You guys get a room

 

[NotInmywatch]

Here is a side by side photo - left side photo taken Nov 24, right side photo taken Dec 29 (ovbiously the hair is longer on Dec 29).View attachment 108056

.

although hair not being trimmed the same exact length before/after can lead to confusion,
there is notorious gain in hair thickness, i.e. reversal of hair miniaturization, in only 35 days of treatment.
fantastic work !

 

[turfboy]

Pigeon, I do not believe Sandalore works by blocking DHT so not the same side effects.

 

[MinervaCGI]

This thread is very promising.