Scientists finally discover sugar that could cure male pattern baldness
- Thread starter Vieo
- Start date
It is not the same product.
The 2-deoxy-D-ribose (2dDR) sugar mentioned in the study is different from the D-ribose found in the products from Amazon or Grainger.
- **2-Deoxy-D-ribose (2dDR)** is an isomer of a deoxypentose monosaccharide, characterized by the absence of a hydroxyl group at the C-2 position. It is a specific compound used in scientific and biomedical research, particularly in studies of angiogenesis and tissue regeneration.
- **D-Ribose**, on the other hand, is a common monosaccharide that is a part of RNA and is widely used as a dietary supplement to enhance cellular energy, especially in people with mitochondrial diseases or heart disorders.
The products mentioned from Grainger and Amazon contain **D-ribose**, not **2-deoxy-D-ribose**. While both are sugars, they have different structures and biological functions. 2-deoxy-D-ribose is a more specialized compound typically acquired through chemical research suppliers, such as Chem-Impex International, which was the supplier used in the mentioned study.
We need to find a supplier and I can do the formula in a pharmacy from Andorra and test it.
cloudsanrain
Established Member
- Reaction score
- 97
I think his hair is just grown out a little bit . Even if it's not the regrowth I can see isn't any thing to get excited about .
- Reaction score
- 11
At this point i am just hoping my son doesn't have to go through this but its looking more likely he will just replace me on this forum and be looking at the same crap in 20 years.
- Reaction score
- 21
Inbe4. It matches minoxidil 2% efficacy in increasing vellous lenght a 0.0005 mm for 1 week!
I’ve been researching, and this sugar is not consumed with food; rather, it’s a sugar that, although it’s true it is naturally produced in the human body, it is generated in very small quantities, and its role is related to the regulation of DNA transcription.
Therefore, I no longer consider its use safe. Having too much of this sugar in the bloodstream could influence critical cellular processes and cause very serious side effects.
Best regards,
Therefore, I no longer consider its use safe. Having too much of this sugar in the bloodstream could influence critical cellular processes and cause very serious side effects.
Best regards,
An excessive increase of 2-deoxy-D-ribose (2dDR) in the blood could have interesting and potentially risky effects from the perspective of organic chemistry and biochemistry, given that this molecule is involved in essential metabolic processes. Here’s an analysis based on the properties of this sugar:
1. Alteration of Cellular Metabolism
2dDR is structurally similar to other essential sugars like ribose but lacks a hydroxyl group at the 2’ position. If its levels were to rise drastically in the blood:
• Competition in metabolic pathways: It could interfere with the pentose phosphate pathway by competing with ribose-5-phosphate, affecting nucleotide production.
• Enzymatic overload: Enzymes such as ribonucleotide reductase could be overstimulated or inhibited, depending on 2dDR concentrations, potentially disrupting normal DNA synthesis.
2. Effects on DNA Synthesis
• Erroneous incorporation into DNA: Excessive levels of 2dDR could lead to abnormal incorporation during nucleotide or DNA synthesis, resulting in genetic lesions or impaired replication.
• Genotoxic stress: An excess of unregulated deoxyribonucleotide levels can cause oxidative stress and DNA damage, factors linked to aging and diseases like cancer.
3. Osmotic Imbalance
As a free sugar in the blood:
• Osmotic effects: Being a small, soluble molecule, excessive 2dDR could disrupt osmotic balance, causing cellular dehydration or impairing the transport of other solutes in the bloodstream.
• Glucotoxicity: Although it is not glucose, elevated levels of free sugars can damage sensitive tissues like the kidneys, nerves, and eyes by generating advanced glycation end-products (AGEs).
4. Formation of Toxic Byproducts
Under high concentration conditions, 2dDR could participate in secondary chemical reactions:
• Maillard reactions: Interaction with proteins or lipids could produce toxic byproducts such as AGEs, contributing to inflammation and tissue damage.
• Oxidative stress: Incomplete metabolism of the sugar could generate reactive oxygen species (ROS), damaging cells and tissues.
5. Potential Accumulation and Renal Effects
• Excretion difficulty: If 2dDR levels exceed the kidneys’ capacity for excretion, it could accumulate, causing renal toxicity or crystallization, similar to other metabolites like uric acid.
Conclusion
Although no specific studies are available on the effects of elevated 2dDR levels in humans, organic chemistry principles suggest that:
• Disrupted metabolism, DNA damage, and osmotic effects are the main risks.
• Prolonged high doses could lead to cellular or systemic damage.
Since this sugar is not routinely metabolized as an energy source, ingesting large amounts could have unforeseen consequences. Therefore, it would be crucial to investigate safe doses and its full metabolic pathway before considering its use.
1. Alteration of Cellular Metabolism
2dDR is structurally similar to other essential sugars like ribose but lacks a hydroxyl group at the 2’ position. If its levels were to rise drastically in the blood:
• Competition in metabolic pathways: It could interfere with the pentose phosphate pathway by competing with ribose-5-phosphate, affecting nucleotide production.
• Enzymatic overload: Enzymes such as ribonucleotide reductase could be overstimulated or inhibited, depending on 2dDR concentrations, potentially disrupting normal DNA synthesis.
2. Effects on DNA Synthesis
• Erroneous incorporation into DNA: Excessive levels of 2dDR could lead to abnormal incorporation during nucleotide or DNA synthesis, resulting in genetic lesions or impaired replication.
• Genotoxic stress: An excess of unregulated deoxyribonucleotide levels can cause oxidative stress and DNA damage, factors linked to aging and diseases like cancer.
3. Osmotic Imbalance
As a free sugar in the blood:
• Osmotic effects: Being a small, soluble molecule, excessive 2dDR could disrupt osmotic balance, causing cellular dehydration or impairing the transport of other solutes in the bloodstream.
• Glucotoxicity: Although it is not glucose, elevated levels of free sugars can damage sensitive tissues like the kidneys, nerves, and eyes by generating advanced glycation end-products (AGEs).
4. Formation of Toxic Byproducts
Under high concentration conditions, 2dDR could participate in secondary chemical reactions:
• Maillard reactions: Interaction with proteins or lipids could produce toxic byproducts such as AGEs, contributing to inflammation and tissue damage.
• Oxidative stress: Incomplete metabolism of the sugar could generate reactive oxygen species (ROS), damaging cells and tissues.
5. Potential Accumulation and Renal Effects
• Excretion difficulty: If 2dDR levels exceed the kidneys’ capacity for excretion, it could accumulate, causing renal toxicity or crystallization, similar to other metabolites like uric acid.
Conclusion
Although no specific studies are available on the effects of elevated 2dDR levels in humans, organic chemistry principles suggest that:
• Disrupted metabolism, DNA damage, and osmotic effects are the main risks.
• Prolonged high doses could lead to cellular or systemic damage.
Since this sugar is not routinely metabolized as an energy source, ingesting large amounts could have unforeseen consequences. Therefore, it would be crucial to investigate safe doses and its full metabolic pathway before considering its use.