- Reaction score
- 1,242
Amino acid sequence RKTGHQICKFRKC with the carboxyl group (n terminal may also work) linked to the amino acid sequence RRRRRRRR with a glycerin linker GGGG.
CXXC5
MSSLGGGSQDAGGSSSSSTNGSGGSGSSGPKAGAADKSAVVAAAAPASVADDTPPPERRNKSGIISEPLNKSLRRSRPLSHYSSFGSSGGSGGGSMMGGESADKATAAAAAASLLANGHDLAAAMAVDKSNPTSKHKSGAVASLLSKAERATELAAEGQLTLQQFAQSTEMLKRVVQEHLPLMSEAGAGLPDMEAVAGAEALNGQSDFPYLGAFPINPGLFIMTPAGVFLAESALHMAGLAEYPMQGELASAISSGKKKRKRCGMCAPCRRRINCEQCSSCRN[RKTGHQICKFRKC]EELKKKPSAALEKVMLPTGAAFRWFQ
CXXC4
MNTNVCVEPGPSPEAPGLPKESHLPEGALNSLVDYNSEMERYRSFATSFYKTNGGAFPQAAKIARITTPIFPSSAAAAAAAARIGMSPWNCDNAATAAAATAMLWGSGGGGGGGGGGGGGGGGGGGGGGGGGGGRKSSSAAASSSASSSSAILPAGGGGGGGGGGSRTSMHHRNDSQRLGKAGCPPEPSLQMANTNFLSTLSPEHCRPLAGECMNKLKCGAAEAEIMNLPERVGTFSAIPALGGISLPPGVIVMTALHSPAAASAAVTDSAFQIANLADCPQNHSSSSSSSSGGAGGANPAKKKRKRCGVCVPCKRLINCGVCSSCRN[RKTGHQICKFRKC]EELKKKPGTSLERTPVPSAEAFRWFF
Other possibilities for the protein transduction domain:
Example:
PTD(RRRRRRRR) <GGGG> DBM(RKTGHQICKFRKC)
RRRRRRRR
YGRKKRRQRRR
DAATATRGRSAASRPTERPRAPARSASRPRRPVE
RQIKIWFQNRRMKWKK
AGYLLGKINLKALAALAKKIL
Vehicle: 50% ethanol, 20% propylene glycol, 30% water
We can reproduce the mouse study to verify which PTD sequence works.
I would suggest adding equol, FGF9, minoxidil, finasteride, dutasteride, RU 5% and Seti 2gr daily dose.
Why? f*** it, just want to know if anything works. Even if such a cocktail won't regrow something f*** everything and wait for Tsuji.