The Eternal Male Pattern Baldness Mistery - Solved

[Mandar kumthekar]

@Armando Jose hairs from body are genetically different than scalp hair ,so one androgen has paradoxical effects on hairs.

 

[Armando Jose]

Hi Mandar, If I give you two hairs, one from body and another from scalp, Do you can detect any difference under microscope or other test? The same if the hairs are from a women or a man? I am curious.....

 

[DHTcel]

Something which intrigues me is when females transition into males and end up bald at a shockingly fast rate. On particular pharmaceutical websites explaining female hair loss, they state that it’s due to a sensitivity to androgens. But why can’t that be applied to men? Men who transition into women have a complete stop of hair loss, and when estrogen is added into the mix they end up regrowing significant amounts of hair (there is a study showcasing the results of spironolactone and estradiol within a six month period).

women have like 95-98% less androgens then men, thats why

 

[Mitko1]

Why people still believe that hair follicles are sensitive to DHT and DHT miniaturizes hair follicles which obviously is not true at all. If it was DHT why we people go bald only on top and not on the sides. And with this occurs in this specific pattern with receding temples and forming a bald spot on the vertex. If DHT was meant to miniaturaze hair follicles it would do it in a diffuse pattern all across the scalp including sides and top.
Everyone has DHT in the scalp but DHT is INCREASED in the balding scalp.
The muscles surrounding the galea match the shape of the Norwood 7 horseshoe. Injecting bottox in the muscles relieve the scalp tension which is highest in the mentioned areas where DHT is increased the MOST.
What is doing Prostaglandin D2 there?
It's obvious that the anti-inflammatory response of the body is triggered.
Why massaging your scalp amd brushing your hair with a wooden brush will take FIBROSIS away and hair will grow back? Three people on the internet have done this and probably many more out of the internet.
Why most men develop balding pattern when they are older when DHT production declines? Because it takes time for fibrosis to develop for some people.

 

[Ikarus]

Why people still believe that hair follicles are sensitive to DHT and DHT miniaturizes hair follicles which obviously is not true at all. If it was DHT why we people go bald only on top and not on the sides. And with this occurs in this specific pattern with receding temples and forming a bald spot on the vertex. If DHT was meant to miniaturaze hair follicles it would do it in a diffuse pattern all across the scalp including sides and top.
Everyone has DHT in the scalp but DHT is INCREASED in the balding scalp.
The muscles surrounding the galea match the shape of the Norwood 7 horseshoe. Injecting bottox in the muscles relieve the scalp tension which is highest in the mentioned areas where DHT is increased the MOST.
What is doing Prostaglandin D2 there?
It's obvious that the anti-inflammatory response of the body is triggered.
Why massaging your scalp amd brushing your hair with a wooden brush will take FIBROSIS away and hair will grow back? Three people on the internet have done this and probably many more out of the internet.
Why most men develop balding pattern when they are older when DHT production declines? Because it takes time for fibrosis to develop for some people.

Lets see if ‘massaging your scalp and brushing your hair with a wooden brush’ works out for you.

 

[Mitko1]

Lets see if ‘massaging your scalp and brushing your hair with a wooden brush’ works out for you.

I don't need this because I don't have hereditary hair loss. My hair loss is very mild and it was caused by fungus and now it's improving and hair is growing back.

Every guy who has zero hair loss has small, squared and flat head. I think that's the way how male pattern baldness occurs. This may be not 100% true but is probably VERY CLOSE to the truth:

Excessive scull bone growth - muscle tension - anti inflammatory response - fibrosis - hair miniaturazation.

Look at Zayn Malik for example. Or Jimmy Neesham when he shaved his head. Compare these guy's heads to someone who is slick bald and see the difference. Look how flat their heads are.

According to common articles - the mechanism of how DHT miniaturizes hair follicles is still UNKNOWN and the genes that are linked to male pattern baldness are still UNKNOWN too. They are unknown because there are NO genes that are causing male pattern baldness directly and dht does NOT miniaturize hair follicles. The only genes linked to male pattern baldness are those which cause bone growth of the frontal and parietal bones and maybe muscle hypertrophy.

The reason why male pattern baldness didn't disappear as a trait is because it has occurred long ago after a male reproduced or did not occur. Today's men generation is balding very young. Ancient men lived on average as I said 35 years old and didn't live long enough to see their first signs of balding or barely lived to see them.
Today's modern world is full of stress, bad food, poluted atmosphere, sedentary lifestyle, exposure of radiation. All those things accelerate both the development of fibrosis and hair loss.
An interesting proving article:www.google.com/amp/s/www.haaretz.com/amp/1.4788442

 

[Ikarus]

I don't need this because I don't have hereditary hair loss. My hair loss is very mild and it was caused by fungus and now it's improving and hair is growing back.

Every guy who has zero hair loss has small, squared and flat head. I think that's the way how male pattern baldness occurs. This may be not 100% true but is probably VERY CLOSE to the truth:

Excessive scull bone growth - muscle tension - anti inflammatory response - fibrosis - hair miniaturazation.

Look at Zayn Malik for example. Or Jimmy Neesham when he shaved his head. Compare these guy's heads to someone who is slick bald and see the difference. Look how flat their heads are.

According to common articles - the mechanism of how DHT miniaturizes hair follicles is still UNKNOWN and the genes that are linked to male pattern baldness are still UNKNOWN too. They are unknown because there are NO genes that are causing male pattern baldness directly and dht does NOT miniaturize hair follicles. The only genes linked to male pattern baldness are those which cause bone growth of the frontal and parietal bones and maybe muscle hypertrophy.

The reason why male pattern baldness didn't disappear as a trait is because it has occurred long ago after a male reproduced or did not occur. Today's men generation is balding very young. Ancient men lived on average as I said 35 years old and didn't live long enough to see their first signs of balding or barely lived to see them.
Today's modern world is full of stress, bad food, poluted atmosphere, sedentary lifestyle, exposure of radiation. All those things accelerate both the development of fibrosis and hair loss.
An interesting proving article:www.google.com/amp/s/www.haaretz.com/amp/1.4788442

If you don’t have hereditary hair loss, why are you commenting on the situation? People who actually suffer with hereditary hair loss know that this doesn’t work. If your solution worked, no one would be suffering with hair loss. It is evident that people with smaller foreheads don’t go recede but that doesn’t cancel out the chance of diffuse thinning occurring. I have a smaller and flat head yet I am diffuse thinning, and have been diagnosed with androgenic alopecia.

Interestingly enough, those external factors you mentioned do not corrolate with hair loss.

Androgens are evidently an issue, it explains why men are more prone to getting acne compared to women along with having hair loss. As soon as people use anti-androgens, acne is no more and the same goes for hair loss. Add estrogen into the mix and people begin to regrow hair.

Why does female pattern baldness exist? Is it due to those external factors?

 

[Mitko1]

If you don’t have hereditary hair loss, why are you commenting on the situation? People who actually suffer with hereditary hair loss know that this doesn’t work. If your solution worked, no one would be suffering with hair loss. It is evident that people with smaller foreheads don’t go recede but that doesn’t cancel out the chance of diffuse thinning occurring. I have a smaller and flat head yet I am diffuse thinning, and have been diagnosed with androgenic alopecia.

Interestingly enough, those external factors you mentioned do not corrolate with hair loss.

Androgens are evidently an issue, it explains why men are more prone to getting acne compared to women along with having hair loss. As soon as people use anti-androgens, acne is no more and the same goes for hair loss. Add estrogen into the mix and people begin to regrow hair.

Why does female pattern baldness exist? Is it due to those external factors?

Female pattern baldness occurs after estrogen levels decline. Then scalp muscles harden and if a woman has the gene for androgen-related scull bone growth it activates but not to the extent of a man because of the lower androgen levels.
About the acne - I started drinking more water and my acne cleared up completely.
You should try improving your lifestyle and nutrition and the WOODEN BRUSH. Drink more water, eat more healthy food rich in zinc, vitamin D, iron, magnesium,sulphur, and you will see improvement or even regrow your diffuse thinning. It's possible that your diffuse thinning is not androgenetic alopecia and you are misdiagnosed. It might be for example vitamin D deficiency.

 

[Ikarus]

Female pattern baldness occurs after estrogen levels decline. Then scalp muscles harden and if a woman has the gene for androgen-related scull bone growth it activates but not to the extent of a man because of the lower androgen levels.
About the acne - I started drinking more water and my acne cleared up completely.
You should try improving your lifestyle and nutrition and the WOODEN BRUSH. Drink more water, eat more healthy food rich in zinc, vitamin D, iron, magnesium,sulphur, and you will see improvement or even regrow your diffuse thinning. It's possible that your diffuse thinning is not androgenetic alopecia and you are misdiagnosed. It might be for example vitamin D deficiency.

Female pattern baldness doesn’t occur from just a decline in estrogen levels. If that was the case, women could just go on HRT to resolve their hair loss but that isn’t the case.

I am going to say this now: drinking water to clear your acne does NOT work. If that was the case, I would have had clear skin years ago and I wouldn’t have needed to go on isotretinoin (I was on it for a month and had to stop as it raised my liver enzymes by 5x). I eat healthy foods, and I take vitamins every single day which include all of the ingredients you stated. I even cut out dairy for years, and that didn’t work. On the other hand, anti-androgens and estrogen has cleared my skin, made my skin smoother and has shrinked my pores. I wasn’t misdiagnosed, either.

 

[NarWhal7]

I actually tried doing scalp massages and exercises for about 4 months prior to taking any sort of drug or chemicals. No wooden brush though.

It did not result in any hair growth.

I have a large sKull. I have norwood 7 pattern.

I've been dermarolling and taking the Big 3 among other supplements for almost a year now and I have regrown to a Norwood 3/4.

I'm just one person though, and I do trust what the scientists and drug peddlers are pushing from personal experience.

Everyone is different and this theory may still be valid for some people's hairloss. I think the reasoning for the "pattern" is still sort of unknown but the idea that some hair follicles can have more sensitive androgen receptors and something in the genetics says that the follicles on top will or won't be sensitive makes sense to me if true.

 

[Mitko1]

The obvious difference between bald head and full head of hair...

 

[Ikarus]

The obvious difference between bald head and full head of hair...

I don’t understand your point...? I mean, in the 4th video listed the mans head shape is similar to the mans in the 2nd video. Yet the one in the 2nd video has hair.

 

[Mitko1]

I don’t understand your point...? I mean, in the 4th video listed the mans head shape is similar to the mans in the 2nd video. Yet the one in the 2nd video has hair.

The galea of the fourth guy is way expanded than the second

 

[Mandar kumthekar]

Hi Mandar, If I give you two hairs, one from body and another from scalp, Do you can detect any difference under microscope or other test? The same if the hairs are from a women or a man? I am curious.....

Scalp hair lacks KRT37 protein which body hair has. I thinks this is just one difference but there are many more differences which yet to be discovered.

 

[Armando Jose]

Scalp hair lacks KRT37 protein which body hair has. I thinks this is just one difference but there are many more differences which yet to be discovered.

https://www.genecards.org/cgi-bin/carddisp.pl?gene=KRT37

Touched,
https://onlinelibrary.wiley.com/doi/full/10.1111/bjd.12278

Keratins of the human occipital hair medulla: androgenic regulation of in vitro hair keratin K37 expression

amazing in vitro Study from 2013 with 3 citations where supossely one of the 54 human keratins are not expressed in all human hairs

BTW , any thing regarding differences between sexes and hair?

 

[itchymadscalp]

My dad is in his 70s and he started to bald 2 years ago. He has been using the same cowboy hat and moto helmet for years (his 20s I think). It excludes scalp expansion.

I’m losing my hair on the top but especially around the ears. It excludes the galea theory.

I’m on Lupron + Estradiol but still losing my hair. With that regimen my muscles should shrink. This excludes muscles theory.

I tried, just for fun, topical testosterone directly on my scalp. The itchy scalp was insane 1-3 hours after. There I want to speak about my theory. When we aging because we are producing less and less testosterone and to counteract that our body, an idiot, make our androgen receptors more sensitive. And because our body is an idiot he doesn’t know when to stop and make them sometimes too sensitive. That’s why some old people have prostate cancer and hairloss.
For the young guys... their androgen receptors might be too sensitive too, but they have specifically bad genes that make them prone to hairloss.

Why women are lucky with their hair ? Because not too much androgens in their bodies. But after menopause the ratio estrogen/testosterone is not so good, and sometimes their AR become too sensitive as well.

Maybe there is a tiny link between the skull expansion and hairloss but the main culprit remains the fuc.ing DHT and sometimes the androgen receptors upregulation.

If you know a way to “lower muscles mass” on/in/around the skull... I would be glad to try. I’ve been a guinea pig for a while now, why stop now?

 

[Mandar kumthekar]

https://www.genecards.org/cgi-bin/carddisp.pl?gene=KRT37

Touched,
https://onlinelibrary.wiley.com/doi/full/10.1111/bjd.12278

Keratins of the human occipital hair medulla: androgenic regulation of in vitro hair keratin K37 expression

amazing in vitro Study from 2013 with 3 citations where supossely one of the 54 human keratins are not expressed in all human hairs

BTW , any thing regarding differences between sexes and hair?

I don't think their is difference in sexes about hair. Hairloss is gene and androgen interaction which is more complex biochemistry. Indo believe if women have androgen as much as men they would bald also like men in same pattern and speed.

 

[Armando Jose]

You know that important androgens are made inside pilosebaceous unit and not with androgens from blood, and there is no differences between sexes.

 

[Mandar kumthekar]

You know that important androgens are made inside pilosebaceous unit and not with androgens from blood, and there is no differences between sexes.

If important androgen is made in pilosebaceous unit then why prepubescent castrate don't get bald? They don't have serum androgen but have pilosebaceous unit,if you were correct they would also go bald ,but they don't.

 

[Mitko1]

https://perfecthairhealth.com/the-ultimate-hair-loss-flowchart-why-we-lose-our-hair/
Very interesting article. You must read this!