Tsuji Riken Hair Primordiums - Final 20 Questions

hellouser

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I'm guessing $10K at least. hair transplant docs love charging by the follicle or FUT. It's my hope Aclaris, Repunzel, or Replicel-Shiseido give us something affordable and makes anything that resembles a hair transplant procedure go the way of Beta Max video casette tapes.

Well, you can go much lower in price, but thats going to depend where the procedure is done and who the doctor is. Most outrageous pricing is easily Dr. Gho though considering the small amounts he uses and the sparse results you get for about $20,000... salt on the wound; he promises regeneration of donor follicles but we all know he's lying.
 

NewUser

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My hope lies with Shiseido and Histogen in the near term. Injections will be expensive enough without waiting on hair germ cells implanted one by one so painstakingly. Cha-ching! And I still think the ultimate fix will come in the form of a topical solution or cream. Like Christano said before, if they can understand the signalling pathways for hair growth, it's just a matter of turning them on.
 
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Tracksterderm

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@Admin I am glad you are involving the community in getting the questions forward to the researchers / companies. Great job!
Have you heard anything back from Tsuj? As all voting and wording of questions are meaningless if there are none to answer them.

Also, from Histogen, they said they would let you know soon about their agreements and then a second interview. Any word back there?

And, great job by all who contributed to the list of questions, I think if we get answers to these it might give hope to all people waiting for better treatments.
 

Blackber

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Please sneak this question in @Admin
us DUPA sufferers have it the worst and this maybe the only thing that can give us a chance. Please do include this in your interview if possible.
Many Thanks
I think the answer to this questions is going to be similar to what Dr. Rolf Hoffmann from Replicel said regarding DUPA: if they can find a patch of your hair that is unaffected by DUPA then theoretically they could clone those hairs (in Replicel's case they'd be multiplying DP cells) if they cant then you might be SOL.

If @That Guy is correct in his assumption that these cloned follicles are considered "new born" (primordiums) then one would assume if you cloned hairs that are affected by DUPA then they would last as long as they did originally i.e. if you didn't start losing your hair until you were 25 years old then you would theoretically get 25 years of hair out of those cloned follicles until your hormones started to affect them again.

My opinion, and I'm no scientist, is that it really comes down to whether or not you have a small patch of hair that is unaffected by DUPA that they can take a biopsy from.
 

FoucaultII

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I think the answer to this questions is going to be similar to what Dr. Rolf Hoffmann from Replicel said regarding DUPA: if they can find a patch of your hair that is unaffected by DUPA then theoretically they could clone those hairs (in Replicel's case they'd be multiplying DP cells) if they cant then you might be SOL.

If @That Guy is correct in his assumption that these cloned follicles are considered "new born" (primordiums) then one would assume if you cloned hairs that are affected by DUPA then they would last as long as they did originally i.e. if you didn't start losing your hair until you were 25 years old then you would theoretically get 25 years of hair out of those cloned follicles until your hormones started to affect them again.

My opinion, and I'm no scientist, is that it really comes down to whether or not you have a small patch of hair that is unaffected by DUPA that they can take a biopsy from.
All stem cells are the age all the rest of the cells is.
If there weren't age-related cell decay, we wouldn't age, would we?
Delaying cell decay is decades ahead ...
 

orkun

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D U P A
Tsuji Other techniques are different.
beard his answer.
we are sad
 

Billy-D2016

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I asked the question a week ago and member Billy-D2016 replied with these two posts:





I still believe we need to hear what Dr. Tsuji has to say on this and what dupa and diffuse donor area sufferers could expect from this treatment.

The word "embryonic" has been used many times in Dr. Tsuji's research, so we need to know what it means. Something that is "embryonic" is by its definition suggestive of being brand new and undamaged.
I'm a Junior Doctor in the UK so i have some basic understanding of biological sciences. I had a read through tsujis method and as i understand it, pluripotent stem cells are not used. The cell used is from the bulb of the hairfollice - the dp cell and these are induced to form hair follices by pairing it with epithelial cells. This replicates what you would see embryologically except that in an embryo, ips cells diffrentiate into dp cells and interact with epithelial cells. It's a bit confusing and i know my explanation is not great. However my knowledge is limited and i could be wrong.. This question should be asked from Dr Tsuji
 

H

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have you heard anything admin or still no word?
 

Billy-D2016

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As a new user: When are these questions being sent in to Tsuji?
They have already been sent i believe. The interview will happen via a telephonic conversation when Dr Tsuji comes back from vacation. The questions have already b
I'm a Junior Doctor in the UK so i have some basic understanding of biological sciences. I had a read through tsujis method and as i understand it, pluripotent stem cells are not used. The cell used is from the bulb of the hairfollice - the dp cell and these are induced to form hair follices by pairing it with epithelial cells. This replicates what you would see embryologically except that in an embryo, ips cells diffrentiate into dp cells and interact with epithelial cells. It's a bit confusing and i know my explanation is not great. However my knowledge is limited and i could be wrong.. This question should be asked from Dr Tsuji
why exactly would you dislike my post?
 

lemoncloak

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Hey people according to this it seems it's possible to (sometimes) extract the necessary cells for the procedure just by plucking hairs from the donor area. How much clinicians are able/willing to put this into practice, I don't know http://www.ncbi.nlm.nih.gov/pubmed/2774646
 

Admin

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UPDATE:

As we all impatiently wait for Tsuji to return from his Japanese Beach Vacation, I wanted to see if anyone here in the community wanted to take the final list above, incorporate the comments and suggestions in this thread, and help us formulate a more targeted final list of questions? Apparently some of them have already been answered and shouldn't even be on the list?

I was going to have @Swoop handle this but he is very busy this and next week, so anyone here want to own the list? When we finalize the questions, Swoop will be rewording them to be "open ended" and encourage a more robust answer from the Doctor.

Admin
 

lemoncloak

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UPDATE:

As we all impatiently wait for Tsuji to return from his Japanese Beach Vacation, I wanted to see if anyone here in the community wanted to take the final list above, incorporate the comments and suggestions in this thread, and help us formulate a more targeted final list of questions? Apparently some of them have already been answered and shouldn't even be on the list?

I was going to have @Swoop handle this but he is very busy this and next week, so anyone here want to own the list? When we finalize the questions, Swoop will be rewording them to be "open ended" and encourage a more robust answer from the Doctor.

Admin
I have a suggestion. Replace question 9 with the "seasonal shedding" question. Angle has been covered in question 6, cycles are essentially covered in the new question and color comes naturally with the formation of melanocytes - Tsuji will know if sth is wrong if the hairs are white.
 

Joan

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Please ask if it will work for DUPA suffers, if beard hair could also be used in this procedure,
Being a female with diffuse hair loss (as I believe is the case with most women suffering from Androgenetic Alopecia), I, too, was wondering if this method would be an option for me. However, I think that question would be answered in Question #10: Who would probably NOT respond to this treatment?
 

orkun

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DUPA
beard transplant grafts are not enough.

Therefore tusuji hair and beard and chest hair culture is very important.
THANKS...
 
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