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No foreign Language please!
Update From The God Himself - Dr. Takashi Tsuji
- Thread starter kingjohn
- Start date
No foreign Language please!
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Man I know that funding does not guarantee that the timeline will be met. I never said that.
In my field of profession timelines are made in an interdisciplinary team with mainly economists and scientists. I kind of find it hard to believe the timeline was sheduled without even consulting the leading scientist or without any scientist at all. And of course timelines are allways very tight sheduled and therefore doomed to be delaied. But since they stated in 2018 the 2020 again i don t believe in a delay of 10 years...
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Dude what the f***.... you argue with the same guy as I was. You said he is wrong.
And i am doing wishful thinking by saying he is wrong???
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Just ignore him. Dude is an a**h** to everyone here.
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Just read your comments, and what I object to.
Lesen macht frei!
Don't get bitter, get better!
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So the ugly loser is a) still acting like an a**h** and b) writing in a foreign language. Tell me, why is the dickhead not banned yet?
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Dude just further proved my point, not realizing that he's one of the Hairlosstalk.com losers. 
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Also Organ Technologies stated in an interview in october 2018 with Takashi Tsuji and Marketing Chef The 2020 commercialization/curing baldness
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If that makes you feel better, keep believing it.Dude just further proved my point, not realizing that he's one of the Hairlosstalk.com losers.
I never thought you were one, but the fact you're doing what you accuse me of doing makes me have second thoughts about your loser status.
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Direct from Kyocera's website.
"Kyocera, RIKEN and Organ Technologies plan to establish cell culture and transplant technologies and develop devices for transplantation, aiming to put the technologies into practical use for the treatment of human alopecia in 2020 in Japan."
https://global.kyocera.com/news/2016/0702_nfid.html
In 2014 Japan passed two new laws
"Under the PMD Act, conditional and time-limited marketing approval can be given to a regenerative medicine product after exploratory clinical trials have demonstrated probable benefit and proven safety. According to these new laws, once a company has demonstrated safety and basic efficiency data in humans and has the cell product manufactured to the standards described within the Pharmaceutical and Medical Devices (PMD) Act, the cell therapy can be given conditional approval for up to seven years. This allows for commercial use with data reporting requirements and potential for national insurance coverage."
From Hairlosstalk own interview.
Yasuhiro Sugimura: CEO of Organ Technologies Inc.
Keiko: Question 13 was removed due to translation difficulties. Question 14: Previous estimates targeted the availability of the technology to be in “practical use” by 2020. Does practical use mean commercial availability to the general public? If so, does this mean that human trials would need to begin a year or two before 2020?
Mr. Sugimura: Yes, as you pointed out, although with an assumption that there is no specific problems, when we say “putting the technologies into use”, we mean “starting to offer it to the general public as a treatment not covered by health insurance”.
Relating to Question #15, we first plan to put the technologies into use in Japan, therefore we need to go through a certain set of procedures as the preliminary steps, in accordance with the “New Act on Regenerative Medicine”, and obtain a regulatory notification on our technology as a Class 2 Regenerative Medicine. The clinical study starts only after we receive that notification. Therefore we are thinking to start a small-scale clinical study to evaluate its safety and effectiveness in 2018.
Keiko: You have already touched on this, but in terms of offering this therapy to people around the world, will a separate regulatory approval process be required in each country?
Mr. Sugimura: Yes, each country requires its own registration/approval. But, as far as we talk about the Japanese market, we are planning to offer it to the general public as a treatment in 2020.
https://www.hairlosstalk.com/news/new-research/hair-primordiums-tsuji-organ-interview-sept2016/
"Kyocera, RIKEN and Organ Technologies plan to establish cell culture and transplant technologies and develop devices for transplantation, aiming to put the technologies into practical use for the treatment of human alopecia in 2020 in Japan."
https://global.kyocera.com/news/2016/0702_nfid.html
In 2014 Japan passed two new laws
- Act on the Safety of Regenerative Medicine (Law No. 85/2013)
- Pharmaceuticals and Medical Device (PMD) Act (Law No. 84/2013)
"Under the PMD Act, conditional and time-limited marketing approval can be given to a regenerative medicine product after exploratory clinical trials have demonstrated probable benefit and proven safety. According to these new laws, once a company has demonstrated safety and basic efficiency data in humans and has the cell product manufactured to the standards described within the Pharmaceutical and Medical Devices (PMD) Act, the cell therapy can be given conditional approval for up to seven years. This allows for commercial use with data reporting requirements and potential for national insurance coverage."
From Hairlosstalk own interview.
Yasuhiro Sugimura: CEO of Organ Technologies Inc.
Keiko: Question 13 was removed due to translation difficulties. Question 14: Previous estimates targeted the availability of the technology to be in “practical use” by 2020. Does practical use mean commercial availability to the general public? If so, does this mean that human trials would need to begin a year or two before 2020?
Mr. Sugimura: Yes, as you pointed out, although with an assumption that there is no specific problems, when we say “putting the technologies into use”, we mean “starting to offer it to the general public as a treatment not covered by health insurance”.
Relating to Question #15, we first plan to put the technologies into use in Japan, therefore we need to go through a certain set of procedures as the preliminary steps, in accordance with the “New Act on Regenerative Medicine”, and obtain a regulatory notification on our technology as a Class 2 Regenerative Medicine. The clinical study starts only after we receive that notification. Therefore we are thinking to start a small-scale clinical study to evaluate its safety and effectiveness in 2018.
Keiko: You have already touched on this, but in terms of offering this therapy to people around the world, will a separate regulatory approval process be required in each country?
Mr. Sugimura: Yes, each country requires its own registration/approval. But, as far as we talk about the Japanese market, we are planning to offer it to the general public as a treatment in 2020.
https://www.hairlosstalk.com/news/new-research/hair-primordiums-tsuji-organ-interview-sept2016/
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Latent homosexual tendencies?
What is it with your offering to blow them?
Is it a loser thing?
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Nah, it's just I don't get losers' humor. It's cringy AF.
My opinion is that science and technology are entering new millennium with Stem Cells, CRISPR/Cas9, 4D printing. There is still long way, but every year we are closer and closer.
New strategy improves efficiency of CRISPR-Cas9 genome editing
https://phys.org/news/2019-02-strategy-efficiency-crispr-cas9-genome.html
Four Ways 4D Printing Is Becoming a Reality
https://www.engineering.com/3DPrint...r-Ways-4D-Printing-Is-Becoming-a-Reality.aspx
All these technology was science fiction before 10 years ago. Now little by little it became reality.
New strategy improves efficiency of CRISPR-Cas9 genome editing
https://phys.org/news/2019-02-strategy-efficiency-crispr-cas9-genome.html
Four Ways 4D Printing Is Becoming a Reality
https://www.engineering.com/3DPrint...r-Ways-4D-Printing-Is-Becoming-a-Reality.aspx
All these technology was science fiction before 10 years ago. Now little by little it became reality.
USA/Canada/Europe regulatory agencies are not retarted at all. There are many scammers. Especially in Latin America, South Asia, Southeast Asia. All advanced countries have strong regulatory laws.
Every year there are maybe 20-30 new groundbreaking scientific papers regarding Stem Cells, CRISPR, 4D printing learning how to produce them in massive numbers with quality and safety control. All these new papers affect hair loss industry as well, because companies will improve their technology instead to shut down whole process.
H
Senior Member
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Lol retarted
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You just say sh*t dont you?
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Dude, are there any arguments you can provide me with?
What is sh*t?
Facts?
I just pity you, losers!
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I've been watching to this thread almost since the beginning (particularly because of studying interests) and I would really like to add my two cents after reading all opinions above (I've also registered just several minutes ago exclusively to participate in this thread).
I have some experience working in molecular lab (though I was on team of cancer research, don't want to dive into details) and I'd say that the human trials in 2019 or even 2020 is unrealistically optimistic. With all my respect to Riken and to Dr.Takashi Tsuji, but based on my pretty humble yet experience, I just don't believe nor I can imagine that the work in lab going so rapidly that a lot of calculations were carried out in a moment. I mean, in this field there just too many processes that physically can't go much faster even with extraordinare money support (I would use here the rule from physical chemistry - the reaction rate is determined by the slowest stage. It just describes the situation the best). I assume they use both in vivo/in vitro and in silico studies and you can never predict which subteam (if I may call it like that) will slow down the whole research. I mean, there just so many unpredictable things. Also if they use calculations of moleculas or something (for example finding the most stable conformers, especially organics), it is just extremely slow work itself (not because of humans, but because even modern computers can't handle this work really fast).
In conclusion, I would be extremely happy to see the progress in the closest future and I honestly hope they'll do it, but 2019-2020 human trials sounds too unrealistic for me. Though, need to mention, I believe it will not be too long time of waiting too, even 5-8 years nowadays is a big deal for research. In my opinion the hair cloning will be ready just in time range above.
I have some experience working in molecular lab (though I was on team of cancer research, don't want to dive into details) and I'd say that the human trials in 2019 or even 2020 is unrealistically optimistic. With all my respect to Riken and to Dr.Takashi Tsuji, but based on my pretty humble yet experience, I just don't believe nor I can imagine that the work in lab going so rapidly that a lot of calculations were carried out in a moment. I mean, in this field there just too many processes that physically can't go much faster even with extraordinare money support (I would use here the rule from physical chemistry - the reaction rate is determined by the slowest stage. It just describes the situation the best). I assume they use both in vivo/in vitro and in silico studies and you can never predict which subteam (if I may call it like that) will slow down the whole research. I mean, there just so many unpredictable things. Also if they use calculations of moleculas or something (for example finding the most stable conformers, especially organics), it is just extremely slow work itself (not because of humans, but because even modern computers can't handle this work really fast).
In conclusion, I would be extremely happy to see the progress in the closest future and I honestly hope they'll do it, but 2019-2020 human trials sounds too unrealistic for me. Though, need to mention, I believe it will not be too long time of waiting too, even 5-8 years nowadays is a big deal for research. In my opinion the hair cloning will be ready just in time range above.
They are not just starting this work though. They have been doing lab work for years. They even talk about overcoming some of the obstacles that take strenuous lab work to solve. I agree that 2020 sounds almost to good to be true, but I don’t think you can really discount press releases from the company itself on the topic of making advancements with the lab work they are doing. While you may have experience in a lab environment, I don’t think you have the whole picture when it comes to how far along they are, and neither do I. So instead of speculating, and throwing around made up time lines, lets just wait for the timeline they gave us to play out. If it comes to fruition, great. If not, then we can only hope that science is progressing, and that one day soon this goal will be realized.