Update From The God Himself - Dr. Takashi Tsuji
- Thread starter kingjohn
- Start date
So sick of hearing this kind of logic
Could be, but one thing is undeniable: Every man is better looking with a full head of hair than he is bald.
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When you're smart and funny you can get women all day. And when you can't, you're either not smart or funny, no matter what you think about yourself. But Yeah, it's much more easy to blame women for your loser-personality.
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You miss every exam and you can't even talk to other women. So no, you are not smart and funny in a woman eyes.
You have to learn to understand that you can't always get what you want, but if you stop feeling sorry for yourself you can get what you need. You don't need to be with a model. Some men have their pick, and some women have their pick. You're not one of those, so you need to accept it and learn to value someone for what's on the inside not what's on the outside.
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Can you shut the f*** up? No one is interested in your fortune cookie wisdom, this is a thread about Tsuji.
I'm trying to help someone who has obvious problems. Grow up loser.
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Do it somewhere else, you double digit IQ brainlet. Good luck with those half-arsed truisms, I don't wanna read them in this thread anymore.
I don't want to see your trashy avatar anymore either, moron.
Edit: You're on ignore now so post all the stupid stuff you want, lowlife.
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The mods are nonexistent around here
Asking them to be even somewhat competent is impossible. They have the intelligence of lab rats.
Just to try and get the tread back on track.
Riken is as we know on their way to try and do some regenerative medicine with hair follicles among other things.
Riken Link
" In the future, this technique could be used for functional skin transplants in burn victims and other patients who require new skin, or even to combat hair loss. Importantly, the lab-grown skin exhibited sustainable hair cycles, indicating functional regeneration."
if we go further in Riken notes
"These first steps toward creating living 3D tissue in the laboratory are truly groundbreaking. RIKEN is leading the way in this field that was considered science fiction just a few years ago, and which could ultimately create a world in which injured tissues are commonly replaced with tissue grown outside the body."
If we then look into the 3D tissue research, then we come upon studies like this Tissue engineering of human hair follicles using a biomimetic developmental approach that shows to ability and challenges of high density.
"we increased the HF density from 81 HF to 255 HF per cm2 (Fig. 4a−c and Supplementary Movie 1) using 3D-printed high HF density molds. The first set of experiments did not result in hair formation; instead, we observed substantial necrosis at the center of the grafts due to lack of host vascularization in the grafts."
And we do already know from Shenseido study that we need that bloodflow/ vascurlarization to the new hair follicles.
"To generate a vascular bed, we encapsulated GFP-tagged human umbilical vein endothelial cells (HUVECs) in the dermis of our HSCs together with the dermal fibroblasts"
"Hair induction in HSCs grafted onto mice
Four to five weeks after grafting our vascularized HSCs at a high follicle density of 255 HF per cm2 onto immunodeficient nude mice, we observed substantial hair growth in the grafts, whereas the HSCs prepared with FB aggregates did not induce hair formation (Fig. 5a, b). In the grafting experiments, we used ten mice per condition. Our vascularization strategy enabled the survival of seven out of ten grafts, both for HSCs prepared with DPCs as well as FBs as a negative control. Grafts from four out of these seven mice successfully generated human HFs, whereas none of the seven mice in the FB control experiment induced hair formation"
As it can be seen there are still challenges with this method.
If we look at the 3D printing technique where it was last year
Scientists at the University of Twente have managed to 3D print structures with living cells, which could boost the field of tissue engineering.
"The researchers wanted to use this technology to produce their 3D structure but the speed at which cells leave the chip was too slow, meaning it would take 17 hours to produce a structure with a size of 1 cubic centimeter."
"This drove the group to look at using jets to speed up the process. They built two jets that were able to safely move fluids 100 to 1,000 times faster than in a microchip. Not only did this mean that the time taken to build a structure was reduced down to around 2 minutes, but by choosing specific combinations of fluids that react, new materials could be generated upon collision.
The researchers used this technique to build 3D structures with a similar internal structure to that of natural tissue that could be filled with cells and fluid. Their approach offers a promising alternative to current 3D printing techniques that tend to use heat or UV light, which damage living cells."
Too me it looks like we have multiple players on the 3D tissue printing area, and this only a few out of many engaged with this area.
Maybe some of the highlighted things with provided higher success rate with high density graft and vascularization is one of the challenges that RIKEN also fight with before they start on human trails, or maybe have solved, and then there is the technical aspect of it that if they used some technique that used 17 hours to make 1 cm^3 and with new technique down to 2 minutes is also some of those changes RIken have hoped for.
Who knows, its a bet anyways on what they are working on around the world.
Riken is as we know on their way to try and do some regenerative medicine with hair follicles among other things.
Riken Link
" In the future, this technique could be used for functional skin transplants in burn victims and other patients who require new skin, or even to combat hair loss. Importantly, the lab-grown skin exhibited sustainable hair cycles, indicating functional regeneration."
if we go further in Riken notes
"These first steps toward creating living 3D tissue in the laboratory are truly groundbreaking. RIKEN is leading the way in this field that was considered science fiction just a few years ago, and which could ultimately create a world in which injured tissues are commonly replaced with tissue grown outside the body."
If we then look into the 3D tissue research, then we come upon studies like this Tissue engineering of human hair follicles using a biomimetic developmental approach that shows to ability and challenges of high density.
"we increased the HF density from 81 HF to 255 HF per cm2 (Fig. 4a−c and Supplementary Movie 1) using 3D-printed high HF density molds. The first set of experiments did not result in hair formation; instead, we observed substantial necrosis at the center of the grafts due to lack of host vascularization in the grafts."
And we do already know from Shenseido study that we need that bloodflow/ vascurlarization to the new hair follicles.
"To generate a vascular bed, we encapsulated GFP-tagged human umbilical vein endothelial cells (HUVECs) in the dermis of our HSCs together with the dermal fibroblasts"
"Hair induction in HSCs grafted onto mice
Four to five weeks after grafting our vascularized HSCs at a high follicle density of 255 HF per cm2 onto immunodeficient nude mice, we observed substantial hair growth in the grafts, whereas the HSCs prepared with FB aggregates did not induce hair formation (Fig. 5a, b). In the grafting experiments, we used ten mice per condition. Our vascularization strategy enabled the survival of seven out of ten grafts, both for HSCs prepared with DPCs as well as FBs as a negative control. Grafts from four out of these seven mice successfully generated human HFs, whereas none of the seven mice in the FB control experiment induced hair formation"
As it can be seen there are still challenges with this method.
If we look at the 3D printing technique where it was last year
Scientists at the University of Twente have managed to 3D print structures with living cells, which could boost the field of tissue engineering.
"The researchers wanted to use this technology to produce their 3D structure but the speed at which cells leave the chip was too slow, meaning it would take 17 hours to produce a structure with a size of 1 cubic centimeter."
"This drove the group to look at using jets to speed up the process. They built two jets that were able to safely move fluids 100 to 1,000 times faster than in a microchip. Not only did this mean that the time taken to build a structure was reduced down to around 2 minutes, but by choosing specific combinations of fluids that react, new materials could be generated upon collision.
The researchers used this technique to build 3D structures with a similar internal structure to that of natural tissue that could be filled with cells and fluid. Their approach offers a promising alternative to current 3D printing techniques that tend to use heat or UV light, which damage living cells."
Too me it looks like we have multiple players on the 3D tissue printing area, and this only a few out of many engaged with this area.
Maybe some of the highlighted things with provided higher success rate with high density graft and vascularization is one of the challenges that RIKEN also fight with before they start on human trails, or maybe have solved, and then there is the technical aspect of it that if they used some technique that used 17 hours to make 1 cm^3 and with new technique down to 2 minutes is also some of those changes RIken have hoped for.
Who knows, its a bet anyways on what they are working on around the world.
I think the only potential fear with cellular cloning is the possibility of cancerous cells multiplying. This is probably why it takes so long to perfect a breakthrough like this since it’s so risky. But truly cloning has gotta be the final frontier, everything else is just placeholders.
Yes, that is a real risk.
Maybe it gets regulated in the future with the whole few cell extraction into like 5.000 hair follicles, maybe it gets solved or maybe there would be a requirement of like 80 - 90 grafts to get 5.000 new graft to try and avoid the about 60 cycles of cell division like mentioned down under.
What are the potential drawbacks of therapeutic cloning?
Many researchers think it is worthwhile to explore the use of embryonic stem cells as a path for treating human diseases. However, some experts are concerned about the striking similarities between stem cells and cancer cells. Both cell types have the ability to proliferate indefinitely and some studies show that after 60 cycles of cell division, stem cells can accumulate mutations that could lead to cancer. Therefore, the relationship between stem cells and cancer cells needs to be more clearly understood if stem cells are to be used to treat human disease.
Correct me if I’m wrong, but doesn’t that only present a risk of the person themself already has cancer? Autologous cells, which this would be, are the safest, so long as the person is cancer free.
They were around to ban you a couple days ago.
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Funny you should say mods are "nonexistent" just a few days after being temporarily banned. I have never understood this suicide by cop attitude, but suit yourself.
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Cancer cells themselves have stem cells and it is one of the things that makes certain types aggressive and resistant to chemotherapy. But back to HairSuit's question, the stem cells in one's own hair follicles must reside within and continue to regenerate for decades. So, you would think that if it is the native follicle with it's own resident stem cells is what is being propagated, the likelihood of cancer would be less. In any event, as long as research in this direction continues, the outcome and various solutions to problems will be revealed. The biggest problem we face here is it takes so damn long and we are beyond tired of waiting.