- Reaction score
- 115
You have to have a benchmark.. a good benchmark would be another treatment option that is currently marketed. In this case, it was clinically superior to isotretinoin. So the question is rather, Why shouldn’t this be marketed just like isotretinoin when it is arguably more superior.
You’re suggestion that 10% is not amazing is a fair one, but that’s your expectation. Considering this has met statistical significance means that there’s a high likelihood that this works and is better than doing nothing at all. (That’s all the FDA look for.. is it 1- safe 2-effective. You could imagine how uncertain drug companies would feel if FDA was mandated to not approve a drug because they “feel” it’s not that great.
Another thing to note is that this is meant to reduce sebum by competing with the androgen receptors. This is my educated guess here, so don’t quote me but I think this would be better at preventing further lesion formation rather than reduction in current lesions by reducing sebum production. Acne which was already formed prior to treatment probably did so because of the excess sebum, any reduction in sebum might not do much anymore as the bacteria has already infected the area.
You’re suggestion that 10% is not amazing is a fair one, but that’s your expectation. Considering this has met statistical significance means that there’s a high likelihood that this works and is better than doing nothing at all. (That’s all the FDA look for.. is it 1- safe 2-effective. You could imagine how uncertain drug companies would feel if FDA was mandated to not approve a drug because they “feel” it’s not that great.
Another thing to note is that this is meant to reduce sebum by competing with the androgen receptors. This is my educated guess here, so don’t quote me but I think this would be better at preventing further lesion formation rather than reduction in current lesions by reducing sebum production. Acne which was already formed prior to treatment probably did so because of the excess sebum, any reduction in sebum might not do much anymore as the bacteria has already infected the area.
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