NorwoodGuardian
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I’m attributing most of that to keto cream and estrogen. Same with the guy in the photos
I use Nizoral shampoo but not much help from it. Maybe a few minutes on scalp is not enough.
I’m attributing most of that to keto cream and estrogen. Same with the guy in the photos
Shampoo is most likely worthless unless you stay in the shower for twenty minutes with it on your hair. You need the 2% cream like the OP uses and leave it on the scalp overnightI use Nizoral shampoo but not much help from it. Maybe a few minutes on scalp is not enough.
What brand pen do you use?I have to admit microneedling at 1.75mm at a high frequency is very painful. If you're bleeding everywhere you're doing it right.
What brand pen do you use?
Does anyone know the binding affinities for ketoconazole? From what I've heard it's a very weak AA.
Good research! Thanks!I'm not sure if this is the answer you're looking for:
Ketoconazole binds to the human androgen receptor - PubMed
Ketoconazole, an imidazole anti-fungal agent, has often produced features of androgen deficiency including decreased libido, gynecomastia, impotence, oligospermia, and decreased testosterone levels, in men being treated for chronic mycotic infections. Based on these potent effects on gonadal...pubmed.ncbi.nlm.nih.gov
"binding of ketoconazole to human androgen receptors (AR) in vitro was also examined. Ketoconazole competition with [3H]methyltrienolone (R1881) for androgen binding sites in dispersed, intact cultured human skin fibroblasts was determined at 22 degrees C. Fifty percent displacement of [3H]R1881 binding to AR was achieved by 6.4 +/- 1.8 (SE) x 10(-5) M ketoconazole. Additional binding studies performed with ketoconazole in the presence of increasing amounts of [3H]R1881 showed that the interaction of ketoconazole with AR was competitive when the data were analyzed by the Scatchard method. It should be noted, however, that the dose of ketoconazole required for 50% occupancy of the androgen receptor is not likely to be achieved in vivo, at least in plasma."
You said that when you stop the regimen you will keep the hair?
that doesn’t sound right to me— with min sure it will fall out without the special min pathway
but if you have male pattern baldness and you stopped applying estrogens anti fungals/androgens and oils wouldn’t you continue to bald just like you would if you were to stop taking propecia
So you microneedle and then apply oils and estrogen?Are you asking in the same sense when you come off like minoxidil you lose all the hair you gained from it?
If this is what you mean then no. You will keep the hair you gained.
But if you're asking me will hair loss progress naturally when you stop? If you're prone yes...over time.
So you microneedle and then apply oils and estrogen?
The estrogen hasn’t shredded your libido? Isn’t it absorbing by quite a bit due to the needling?
Dude, wet your hair, put the shampoo, leave the shower, wait 20 minutes, then enter again to the shower , etc . omg.Shampoo is most likely worthless unless you stay in the shower for twenty minutes with it on your hair. You need the 2% cream like the OP uses and leave it on the scalp overnight
Dude, wet your hair, put the shampoo, leave the shower, wait 20 minutes, then enter again to the shower , etc . omg.
Let put this very, very clear, Ketoconazole it is an antiandrogen. So you are using a topical antiandrogen that most probable will go systemic in the long run , if you are using a cream and let it all night. .
I understand, but I was referring to him only shampooing for 5 minutes. Yes, you can leave the shower and come back. But why not make it easier on yourself and put the cream on? Then wash it off after a few hrs or so.Dude, wet your hair, put the shampoo, leave the shower, wait 20 minutes, then enter again to the shower , etc . omg.
Let put this very, very clear, Ketoconazole it is an antiandrogen. So you are using a topical antiandrogen that most probable will go systemic in the long run , if you are using a cream and let it all night. .
Damn that’s crazy good results. Do you know his regimen/dosage with those two?Just for some motivation: this is another guy who went on the same regime I did. He was coached by Taeian with a custom diet and the topical regime.
Of course his diet was most likely a lot more nutrient dense than mine but these results were gained literally in a few months.
He himself used ketoconazole 2% cream and bi-estro. The rest of his topical stack wasn't revealed to me.
Damn that’s crazy good results. Do you know his regimen/dosage with those two?
I’m seeing a pattern of diffuse hair loss benefiting a lot with anti androgenic regimens. Plus estrogen for growth. But that’s feminizing so it’s risky.
Is diffuse hair loss with no hairline recession a result of mostly androgens attacking follicles rather than the typical dht pattern?