All we need to know about RU58841

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peloncete1989

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Enden said:
Myself...

Very glad to heard this, bro.

Somedays, you know, with this sh*t, you lose the hope of found something that works... and it's nice to know people with good results.

Today was a hard day.
 

Ende

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I still have diffuse thinning.. but all my hairs thickened up drastically with RU treatment, and they're maintaining. I'm using hGH as a growth stimulant at the moment, and I'm going to use AHK-Cu as well to reverse scarring. These are meant to be temporary treatments. I believe that I'll be able to maintain the hair with RU58841 - or CB-03-01 only. The latter is preferred, but it's very expensive.
 

Megadeth

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Is anybody interested in buying my remaining RU58841 supply? I bought 5 grams from OC about two months ago, and I have 3.7 grams left. I have kept it refrigerated since I received it. I have not used it consistently enough to have seen results, but I have some concerns about the possible long term use of anti-androgens, which is why I want to sell, even though I experienced no bad side effects while on it.

I would sell for $130 shipped. I feel like this is a good price, considering it is $260 shipped for 5 grams. I will ship with an ice pack and ship overnight to ensure it is kept at a cold temperature.

PM me if interested.
 
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Any french interested in knowing more ? I assume it would be easier to know if I was in France. Once could call the RU company and ask for a short interview with Dr Dr. Sewaya. The point is to find out whether there are some really undesirable side effects that made this company stop producing it or there are other reasons. Some say the company itself was bought or closed. I cannot verify this. However, if this is the case then it does not necessarily have to do with this particular product as it is a big company and public companies tend to be privatised at some point.


In fact it's only a history about “healthâ€￾ VS “super profitsâ€￾.

The Roussel UCLAF lab, member of the group HMR (Hoechst-Marion- Roussel) was force to fusionate with the Rhône-Poulenc - Rorer group to create Avensis in 1999.
That is the reason why 169 molecules in development and coded RU (Roussel Uclaf) were abandoned or sold off by the HMR group.

Reason: the drugs from this innovative molecule is not enough profitable, and cost too much in research. So they give up RU 58841 project, which represented years of research, instead of finalize the product.
They highlight possible side effects, but in fact the group has decided to liquidate all its activities in endocrinology.

However, Proskelia research, (member of Avensis group) took the project under the name PSK3841. I just know that it went to Phase 2. But since then, there’s s no news from them... Some say that they drop of the project but in fact they are searching for a big group to buy their research.

Sorry for my bad english... :whistle:
 
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I made some research on RU58841, and I found that it's a derivate of nilutamine.
Here is an extract of a French study about Nilutamine:

Many derivatives of nilutamide as the compound RU58841, were developed in Europe to treat locally acne and alopecia.
The RU58841 has a half-short life of less than 1 hour. Its local application not only avoids extensive hepatic metabolism, but also provides effective treatment to the skin without evidence of an anti-androgen which is due to the formation of the active metabolite.
Previous studies on organic analogues of nilutamide have shown that a large number of substituents at this position could lead to a significant improvement in the value of RBA. The most prominent examples are analogues containing N-hydroxyalkylchain (molecule RU58841) and N-cyanomethyl (molecule RU58642). Indeed, these two molecules not only recognize AR with values of RBA important, but they show promising anti-tumor activities in biochemical studies in vitro and in vivo.
The case of the component RU58841 is interesting, since it was developed to treat skin diseases such as acne, hirsutism and alopecia.

That's why Flutamide (Eulexin), nilutamide (Anandron, Nilandron) and bicalutamide (Casodex), are potentially good cures because they are nonsteroidal, pure antiandrogens, derivated from nilutamide.
Hoever, Flutamide is the oldest and has more unwanted side-effects than the others. Bicalutamide is the newest and has the least side-effects. But I don't think someone has already tested it...
 

peloncete1989

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Enden said:
I still have diffuse thinning.. but all my hairs thickened up drastically with RU treatment, and they're maintaining. I'm using hGH as a growth stimulant at the moment, and I'm going to use AHK-Cu as well to reverse scarring. These are meant to be temporary treatments. I believe that I'll be able to maintain the hair with RU58841 - or CB-03-01 only. The latter is preferred, but it's very expensive.

That's what I'm searching, thickering on my diffuse.

I still having a lot of hair but miniaturized (without colour and thin). Legit hGH it's difficult to get, at least in Europe..

I hope RU give us some years, until a finally cure.

Where did you get your RU?
 

Ende

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Ball Pattern Menless said:
I made some research on RU58841, and I found that it's a derivate of nilutamine.
RU58841 is a benzonitrile derivate, and it belongs to a group of drugs called phenylimidazolidines.

This is the RU58841 patent. Example 58 - page 16 is RU58841.
 

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Ende

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peloncete1989 said:
Legit hGH it's difficult to get, at least in Europe..

I hope RU give us some years, until a finally cure.

Where did you get your RU?
It's easily available on the black market, in most of Europe.

OC.
 

Ende

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Ball Pattern Menless said:
However, Proskelia research, (member of Avensis group) took the project under the name PSK3841. I just know that it went to Phase 2. But since then, there’s s no news from them... Some say that they drop of the project but in fact they are searching for a big group to buy their research.
The drug is now owned by Prostrakan, and R&D has been on hold for a very long time. I think it's unlikely that RU58841 will reach the market, but the patent expires very soon - if it hasn't already done so, and a large pharmaceutical company - located in India, has recently filed a patent on new delivery solutions. So maybe we're in for a surprise.
 
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I hope so because it's not easy to make our own solution with RU.
We are not able to tell which dosage is the best and if the RU is really pure...
So I think I will wait until a lab release a good product with RU inside.
When I read some member stories about RU it's really attractive but here in France, it is very difficult to get all the product needed for the appropriate solution... even the rogain foam ! :(
 

Ende

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Ball Pattern Menless said:
I hope so because it's not easy to make our own solution with RU. We are not able to tell which dosage is the best and if the RU is really pure...
That's not true, but I admit that it's a while since RU58841 from the current suppliers was tested, and that some people are questioning the legitimacy and purity. Stay away from yellow RU - and OC's new compound, and you'll probably be fine. OC's compound has never been tested, but it appears like they're buying from KC. Their new compound doesn't look like RU, so people should stay away until we have verified that it's legit.
 

peloncete1989

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Enden said:
Ball Pattern Menless said:
I hope so because it's not easy to make our own solution with RU. We are not able to tell which dosage is the best and if the RU is really pure...
That's not true, but I admit that it's a while since RU58841 from the current suppliers was tested, and that some people are questioning the legitimacy and purity. Stay away from yellow RU - and OC's new compound, and you'll probably be fine. OC's compound has never been tested, but it appears like they're buying from KC. Their new compound doesn't look like RU, so people should stay away until we have verified that it's legit.

So, shouldn't we buy to Kou-ting Chemichal or Kou-ting China?
 

peloncete1989

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I've asked about prices of RU to 6 companies.

K.outing Chemichals --> 319.04 USD/ 10 grams

Lang Chemichals --> 600 USD / 10 grams

K.outing China --> 238.09 USD / 10 grams

Faith Eagle --> 383.80 USD / 10 grams

Ontar.io Chemichals --> 350 USD / 10 grams

I wonder... this difference of prices are normal?
 

peloncete1989

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I'm going to do my first order, and I'm a little bit worried about the quality of the RU...

I know the Kane's was check it, but I'm not sure... any advice guys?
 

peloncete1989

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[quote="Enden]I had been using minoxidil for half a year or so. Significant regrowth should be seen within 4 months in if you're a great responder. I didn't see much change with Propecia and Rogaine, but 3 weeks with RU58841... I've never seen anything like it. Drastic, cosmetic improvement...[/quote]

It looks like if you were talking about me... I hope the last part will be the same for me...

:bravo:
 

Ende

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Ball Pattern Menless said:
Hey did you guys have already seen this pharmaceutical document about some way to prepare RU ?
I don't understand every thing as I'm french, and it's quite a complicated technical language inside, but it's definitly an interesting Doctor.
If someone could give an eye on it , it would be great.

Thanks

A different protocole for the preparation of RU
Thanks! I'll definitely take a closer look at that study.
 
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