Apparently Tsuji has started clinical trials

froggy7

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Honestly if you're under 50 there is a pretty good chance you can reach longevity escape velocity. There are a ton of therapies on the horizon which can rejuvenate the body (reverse aging). For example epigenetic reprogramming which is going into non-human primate clinical trials in the next year or 2. Then there is senolytic therapies which are already in human clinical trials and may be available to the public within the next 10 years.


Unlike hair loss, people actually give a sh*t about curing aging lol. I mean Jeff Bezos literally started a company called Altos Labs to cure aging.

Bezos is a bald *** mofo but he never funded hair loss research at all. He is funding anti-aging research though.
What if you get sick and you simply don't have a chance to live the next 10 years? cryonics offers at least minimal chances
 

Pacho

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just lol if you are not willing to spend your life saving and the college funds of your children for a thick norwood 1 hairline

id even sell my house, i rather be a homeless dense norwood 1 guy then a rich bald guy
 

trialAcc

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just lol if you are not willing to spend your life saving and the college funds of your children for a thick norwood 1 hairline

id even sell my house, i rather be a homeless dense norwood 1 guy then a rich bald guy
Imagine actually thinking like this. Scary stuff. Hair isn't going to solve your problems dude, not with this mindset.
 

trialAcc

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Honestly if you're under 50 there is a pretty good chance you can reach longevity escape velocity. There are a ton of therapies on the horizon which can rejuvenate the body (reverse aging). For example epigenetic reprogramming which is going into non-human primate clinical trials in the next year or 2. Then there is senolytic therapies which are already in human clinical trials and may be available to the public within the next 10 years.


Unlike hair loss, people actually give a sh*t about curing aging lol. I mean Jeff Bezos literally started a company called Altos Labs to cure aging.

Bezos is a bald *** mofo but he never funded hair loss research at all. He is funding anti-aging research though.
Even if you are over 50, you will be bought time for the science to catch up. I wouldn't suspect anyone healthy under the age of 60-65~ right now who doesn't run into medical complications in the next decade or so will live less then 130-140. Those extra 30-40 years will decide if you or all of us escape.

The trick is not getting unlucky enough to die of health complications or accidents in the next 20~ years.
 

Chads don't bald

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If epigenetic reprogramming works in adult humans the way it works in human cells, it could theoretically make all the cells in your body ~25 yrs old irregardless of how old you are. So in that case it could help those above 50 too.

The only issue is that there are types of extracellular damage you need to treat as well, like arterial plaques. There is also cancer. Epigenetic reprogramming won't prevent cancer as it doesn't prevent/reverse mutations in the DNA.

So basically we will need comprehensive rejuvenation and I'm not sure whether that will be possible in the next 20 years. That's why I'm not so optimistic for those above like 60 or so. Those people should probably invest in cryonics just in case.
 

fashy

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I don't understand how there are so many people that wish for us to stop aging/ live infinitely. Like this is legitimately one of most retarded and dangerous roads humans can undertake going forward. These kinds of ambitions are only lusted after by insecure losers who don't realize that living 30,40, howevermany years more is not going to make their lifes and their base experience any better. Quality over quantity.
 

fashy

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The statistical 80 years of life is definitely too short for me, life will be easier and easier cryonics has little chance of success, but lying in the grave, you have no chance, these are the facts, everyone has their choice and you probably won't say that 50k $ is excessive cost?

How the f*** do you know this? It's certainly not from personal experience, so have you actually met any people aged 70+ that complain about how they wish they had another 50-60 years, because I can assure you most elderly people are more than satisfied with the course and duration of their life and generally live with the disposition that there's nothing more to be gained and lived in life than what they already have. They have a certain calm demeanor in the face of death because they are wise enough after years of lived experience to appreciate its inevitability.
 

Chads don't bald

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I don't understand how there are so many people that wish for us to stop aging/ live infinitely. Like this is legitimately one of most retarded and dangerous roads humans can undertake going forward. These kinds of ambitions are only lusted after by insecure losers who don't realize that living 30,40, howevermany years more is not going to make their lifes and their base experience any better. Quality over quantity.
Sorry your life sucks bro but mine kicks *** and I want to keep living it forever
 

froggy7

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I don't understand how there are so many people that wish for us to stop aging/ live infinitely. Like this is legitimately one of most retarded and dangerous roads humans can undertake going forward. These kinds of ambitions are only lusted after by insecure losers who don't realize that living 30,40, howevermany years more is not going to make their lifes and their base experience any better. Quality over quantity.
there is no point in listening to old people because they lived in completely different circumstances than ours
 

coolio

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there is no point in listening to old people because they lived in completely different circumstances than ours

LOL

Read some history. Very little of what's going on today is really new.
 

froggy7

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LOL

Read some history. Very little of what's going on today is really new.
seriously? 100 years ago was stemson, cryonics, Tsuji? seriously ? did you have what now? there used to be one big sh*t
 

trialAcc

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If epigenetic reprogramming works in adult humans the way it works in human cells, it could theoretically make all the cells in your body ~25 yrs old irregardless of how old you are. So in that case it could help those above 50 too.

The only issue is that there are types of extracellular damage you need to treat as well, like arterial plaques. There is also cancer. Epigenetic reprogramming won't prevent cancer as it doesn't prevent/reverse mutations in the DNA.

So basically we will need comprehensive rejuvenation and I'm not sure whether that will be possible in the next 20 years. That's why I'm not so optimistic for those above like 60 or so. Those people should probably invest in cryonics just in case.
If you listen to any leading longevity expert talk, the goal isn't to solve those problems in the next 20 years. It's to push that 20 years into 30-35 years and solve it in the next 30-40.
 

trialAcc

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I don't understand how there are so many people that wish for us to stop aging/ live infinitely. Like this is legitimately one of most retarded and dangerous roads humans can undertake going forward. These kinds of ambitions are only lusted after by insecure losers who don't realize that living 30,40, howevermany years more is not going to make their lifes and their base experience any better. Quality over quantity.
Our lives right now are designed to be 45~ of "prime" years, followed by a decline for another 40 years. That is an artificial construct based on our current situation. Do you not think that other humans were saying that exact same thing as you are now when humans routinely lived into their 40s max?

Those "Insecure losers" realize that by and large the quality of your life is dictated by your physical and mental health during your years alive. They are trying to correct that so that more quality can be achieved in whatever the quantity ends up being. I find it much more insecure that people can't possible fathom what they would do with their lives if they lived beyond a stock base number. You live in a box right now and can't imagine leaving it.

There isn't many people who have existed that were healthy in their old age who didn't wish for more time on earth. It's only the unhealthy and tired one's who accept that it's their time to go. Remove the pain/tired/unhealthy and you have people who are excited for another day.
 

Micky_007

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If you listen to any leading longevity expert talk, the goal isn't to solve those problems in the next 20 years. It's to push that 20 years into 30-35 years and solve it in the next 30-40.

Not really. Jeff Bezos has joined the longevity game, and with the amount of money him and Yuri Milner have (some of the richest men in the world) I highly doubt they will wait until 30 to 40 years when they would both be probably dead unless they solve it.

We also know Jeff Bezos is quite a selfish person so I know he wouldn't be working on this tech if it wasn't within reach in his natural lifetime and that he also wouldn't share this information with everyone so "everyone" solves aging.

Even the company he is heavily invested in with Yuri Milner, called Atlos Labs you won't find a website for it on the internet.
 

Super Metroid

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How confident does a researcher / company have to be to actually enter the trials? They cost a lot of money and generate publicity, so in case of failure, your reputation is at stake. Is it possible that Tsuji already has done some experiments on humans and therefore has a hint of how the trials will go? Would that be ethically acceptable? Are the trials the first real possibility to test the solution?

Many companies fail in trials, so they don't all enter will complete certitude. Why is everybody so sure this will work out?
 
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