And you'd be wrong. This isn't a hair transplant.
dNovo new promissing player in the stemcell race
- Thread starter byebyehair
- Start date
do You know how they are going to get the right hairline?
- Reaction score
- 179
i dont think so, try to find the personel that can implant such organoids, a normal hair transplant surgeon wont suffice i think
- Reaction score
- 179
the organoids still need the blood supply, there needs to be studies whether too many injections could lead to necrosis.
also instesd of worrying about the aestetics of hair lines people should wonder how they are addressing the fact that the follicles might not be androgen resistent and minaturize again due to high levels of surrounding DHT and due to potentially not having few enough ansrogen receptors like the donor zone(because rhey are not derived from donor but completely different type of cells which might severely alter epiginetic profiles)
The idea that blood supply limits how many grafts can be implanted at one time is mostly, if not entirely, incorrect. Zarev has done up to 14,000 in one session.
The limiting factors are the stamina of the surgeon, the size of the punch for density, the comfort of the patient, shock loss from excessive trauma not blood supply, and of course the availability of grafts and how long they survive before being implanted, so the speed at which the surgeon works.
I'm pretty sure Stemson has already stated that they will be able to make them dht resistant, I think this is the easiest part of the whole operation yet everyone is hung up on it. They wouldn't even be doing this if they couldn't make them dht resistant. Other companies are multiplying cells from the donor zone that after already dht resistant. I think Stemson said their DP cells would likely be dht resistant without any reprogramming because they don't go through the genetic programming that makes scalp hairs sensitive to dht in the first place.
I assume they are trying a new twist, but since they are still very early (mouse model) I guess it is still speculative and they don’t have a clue if it’s going to work or not. So they are after funding to try some stuff.
Also, since their website is basically a marketing flyer with not many tech info shared it’s hard to know.
This guy is not a joke. He got PhD at 2 top 10 universities in USA (Stanford and Harvard), so I am pretty sure that he is not naive and knows that many companies previosly tried and failed with injecting dermal papilla cells.
Dermal papilla cells are most important cells in hair follicle, so if he knows how to reprogram them without losing their inductivity, then there is no reason why these cells can’t grown in human heads.
The hairs in his mice model are human stem cells (all companies previosly mixed human with mice stem cells to grown hairs on mice) are best so far that I had ever seen...
They are considering funds, not getting.
Is this a one man company? Who are the others in his team? Is there any information? Looks too naive from my perspective...
- Reaction score
- 179
reminding that someone died from a mega session in india due to infection
They're not naive. They went through Y Combinator. For that alone I have more faith in this company than anything else.
- Reaction score
- 179
joy where is your phd from you said again? what's that? you are saying you are just a rando who made an account on an online forum calling multiple phd holders and scientists naive?
- Reaction score
- 188
dNovo Emerges From Stealth With Its Potential Cure for Hair Loss
dNovo Inc., a Silicon Valley company developing a cure for hair loss by generating personalized hair stem cells, emerged from stealth today and announ
www.businesswire.com
pls can they inject muh blood into muh scalp and give me hair....now!!!!!!! right now!
Or I do it muhself?
dNovo Emerges From Stealth With Its Potential Cure for Hair Loss
dNovo Inc., a Silicon Valley company developing a cure for hair loss by generating personalized hair stem cells, emerged from stealth today and announwww.businesswire.com
Definitely exciting. Wish this guys the best
You ok bruh? Lol
I should add that it’s nice that they are able to reprogram cells to become derma papilla without raving to resort to IPSCs, Stemson should take not as this supposedly would make their processes much more simple.
Yet I should also add that that hair in the mouse pic shared by dNovo was “generated” (more likely stimulated) using “human” stem cells (whatever that means) not DP cells as per their own press release and website indicate.
They already are able to get those DP cells via direct means since at least Q2 2021 and yet there are no mouse pics after that so I assume dNovo is having their own set of problems.
Yet I should also add that that hair in the mouse pic shared by dNovo was “generated” (more likely stimulated) using “human” stem cells (whatever that means) not DP cells as per their own press release and website indicate.
They already are able to get those DP cells via direct means since at least Q2 2021 and yet there are no mouse pics after that so I assume dNovo is having their own set of problems.
Last edited:
Here we go again lol
Yes but the issue with this is how difficult what they are doing is. While hypothetically perfect, this task has been thought of by everyone in the field and no one has been able to crack it.
When Roeysdomi is making more sense then you it's time to hang it up bud, he's not wrong.