Dr. Tsuji Kyocera, Riken Research, Organ Technologies Form Regenerative Hair Research Team

That Guy

Banned
My Regimen
Reaction score
5,361
7drHiqr.gif
 

champpy

Experienced Member
Reaction score
1,118
Kyocera launched a joint research to develop a regenerative medical treatment for hair loss, targeting practical use in 2020
08 August 2016

The partnership aims to develop technologies and products for treating hair loss by regenerating hair follicles. Because no existing treatment can increase the number of hair follicles, any viable method of regenerating hair follicles has great potential to succeed.

The joint research works on a technology to collect stem cells from the patient’s own hair follicles, followed by the processing of these follicles and autografting on the same patient. For the treatment of androgenic alopecia (the most common type), a small number of hair follicles will be collected, from which stem cells will be isolated, cultured and amplified to produce hair follicle germ. The regenerated hair follicle germ will be packaged and delivered to a medical facility for use in transplantation therapy for the patient. The method furthermore allows control of the hair color by adding pigment stem cells, and the number of hair follicles regenerated.

Kyocera is responsible for technical aspects such as the development of cell processing devices. While various methods are under evaluation, Kyocera’s piezoelectric technology is of particular interest as a means of discharging small amounts of viscid cells in a precise manner during the cell processing process.

Kyocera is expanding its expertise in creating medical components for orthopedic joint replacement and dental implants to support this future application of regenerative medicine.

Kyocera, RIKEN and Organ Technologies are aiming for clinical research in Fiscal Year 2019 (Year ending March 31, 2019), with the goal to put the technologies into practical use in 2020.




Source:

http://www.kyocera.co.uk/index/news...ZGljYWxfdHJlYXRtZW50X2Zvcl9oYWlyX2xvc3M~.html



I honestly don't think they'd make the same mistake twice in saying that they plan to release this treatment in 2020. This was an update to the original press release (just happened 6 days ago, and has already been mentioned in here). It seems so surreal, but I honestly think they're gonna make this avaliable in 2020.

Great find yep 78! It says they also intend to control pigmentation. Hummm. By the time this comes out ill be getting lightly gray. Wonder of they can engineer me some dark brown locks for my bald head place. Id love to have eternal dark hair
 

mr_robot

Experienced Member
Reaction score
384
Btw when they say piezoelectric what they basically mean is using the same kind of technology used by inkjet printers, it will let them precisely deposit the cultured cells in a grid where they will form the germ where they can then be extracted mechanically. So technology wise looks like they have most of it covered, it just about putting it together. I just hope the science works out.
 

Torin

Established Member
My Regimen
Reaction score
73
Hello guys,

Would any of you in the know like to guess the answers to these questions of mine? For I think they will need to be answered and result in ideal scenarios by Riken for this to be the cure we're looking for.

These are some questions I would like to ask Dr. Tsuji if I had the possibility.

1. Have they worked out how to influence the direction of new hair shaft growth? Hairs grow in different directions according to their location on the scalp and even based on the individual's own characteristics. How will they accomplish this task?

2. Can they treat areas if scalp that already have a lot of hair covering it (relatively speaking)? For example, could a 1cm2 area of scalp containing 90+ growing hairs still be treated?

3. Will the hair germs inherit any damage or ageing that the donor hairs might possess, or will they literally start from "Day One" as if in a new born baby? This is especially important for those with weak/unstable donor areas.
 
Last edited:

tdag

Member
Reaction score
35
They're aiming for 2020 practical use. But how realistic is that? That is probably a very optimistic timeline. Ill just be happy if it works and comes out within 10 years.
 

Blackber

Experienced Member
Reaction score
604
No point in constantly debating the release of this. It's years away either way.

I think it's pretty clear their intent is for a commercial release in 2020. Delays are likely in any situation, so I wouldn't expect a 2020 release - although that'd be great.

Multiple press releases state a release of 2020. If you don't think a multi-billion dollar company like Kyocera is privy of what the intended release date is with their partners you don't have a clear understanding of how the business world works.

Again 2020 is their intent, whether it happens remains to be seen.

Why don't we get back to a more constructive conversation.....
 

Torin

Established Member
My Regimen
Reaction score
73
Why are you so concerned with the direction of the hairs? And why do you think it would be any different than when your "natural" hairs sprouted? In theory, the new follicles will develop and emerge just as your original hairs did since they're starting from germs.

In the mouse studies, Dr. Takashi had to use nylon threads to guide the direction of the growth of the new hairs.

He has not yet elucidated how they will get the direction right without using threads.

Maybe something underneath the skin will take place naturally so that the hair grows the right direction. But then that begs the question why the need for the nylon threads in the studies?
 

tdag

Member
Reaction score
35
No point in constantly debating the release of this. It's years away either way.

I think it's pretty clear their intent is for a commercial release in 2020. Delays are likely in any situation, so I wouldn't expect a 2020 release - although that'd be great.

Multiple press releases state a release of 2020. If you don't think a multi-billion dollar company like Kyocera is privy of what the intended release date is with their partners you don't have a clear understanding of how the business world works.

Again 2020 is their intent, whether it happens remains to be seen.

Why don't we get back to a more constructive conversation.....

ehh not much else to talk about until we get more information. I definitely believe they are saying it will be commercially available in 2020, but maybe they are intentionally being overly optimistic for whatever reason. What I am saying is one side of this argument is latching onto the press release statements and the other is latching on to Tsuji's still recent comments. Its quite possible that both sides are right and Tsuji is being a little conservative and Kyocera is being overly optimistic.
 

Blackber

Experienced Member
Reaction score
604
In the mouse studies, Dr. Takashi had to use nylon threads to guide the direction of the growth of the new hairs.

He has not yet elucidated how they will get the direction right without using threads.

Maybe something underneath the skin will take place naturally so that the hair grows the right direction. But then that begs the question why the need for the nylon threads in the studies?
I'm sure this will be answered at some point, you've asked this question about 10 times lol. @Swoop said HairLossTalk.com is going to try to set up a Q&A with Tsuji, maybe we can get an answer then.

I thought I remember someone finding paperwork from Tsuji earlier in this thread that stated they'd use a material other than nylon that the human body can degrade.

Regardless if you were a NW7 and this treatment could bring you back to a NW0 would you really care to have some strings hanging out of your head for 2-3 weeks? It would be a small price to pay for a full head of hair. We don't even know what the "strings" would look like.
 

Torin

Established Member
My Regimen
Reaction score
73
I'm sure this will be answered at some point, you've asked this question about 10 times lol. @Swoop said HairLossTalk.com is going to try to set up a Q&A with Tsuji, maybe we can get an answer then.

I thought I remember someone finding paperwork from Tsuji earlier in this thread that stated they'd use a material other than nylon that the human body can degrade.

Regardless if you were a NW7 and this treatment could bring you back to a NW0 would you really care to have some strings hanging out of your head for 2-3 weeks? It would be a small price to pay for a full head of hair. We don't even know what the "strings" would look like.

Yeah I know I've asked this questions many times because I think it's important.

I personally wouldn't mind having threads, but I don't think it would be practically possible to have hundreds of threads hanging off your head.

Furthermore, if they had to guide the direction of every single thread manually, it would be a lot more time consuming and technically challenging than if the germs could just be injected and grow organically in the correct direction.
 

Blackber

Experienced Member
Reaction score
604
Yeah I know I've asked this questions many times because I think it's important.

I personally wouldn't mind having threads, but I don't think it would be practically possible to have hundreds of threads hanging off your head.

Furthermore, if they had to guide the direction of every single thread manually, it would be a lot more time consuming and technically challenging than if the germs could just be injected and grow organically in the correct direction.

No one will be able to answer this except Tsuji. They have to have a method of doing this or a good working theory otherwise they wouldn't be thinking of bringing it to market.
 

Ken1983

Established Member
Reaction score
28
Why are you so concerned with the direction of the hairs? And why do you think it would be any different than when your "natural" hairs sprouted? In theory, the new follicles will develop and emerge just as your original hairs did since they're starting from germs.
Tsuji developed a biodegradable guide which the makes the hair grow in the right direction- without it cysts would form. In the study they used tape and a nylon thread as a prototype to hold the primordium in place.
 

Blackber

Experienced Member
Reaction score
604
Tsuji developed a biodegradable guide which the makes the hair grow in the right direction- without it cysts would form. In the study they used tape and a nylon thread as a prototype to hold the primordium in place.
I just did a search and saw you were the one I was referring too.

Do you have a source or link? Not that I don't believe you, I'd just like to educate myself.

Thanks!
 

jc3303

Established Member
My Regimen
Reaction score
197
Wasn't that info in Tsuji's latest published paper?

And I think there's a link to it somewhere in this thread
 

Armando Jose

Senior Member
My Regimen
Reaction score
983
I just did a search and saw you were the one I was referring too.

Do you have a source or link? Not that I don't believe you, I'd just like to educate myself.

Thanks!

http://www.nature.com/ncomms/journal/v3/n4/full/ncomms1784.html

"To prevent epithelial cyst formation and associations between the epithelium of the host skin and the bioengineered hair follicle germ, we developed an inter-epithelial tissue-connecting plastic device that used a nylon thread as a guide for the infundibulum direction via insertion into the bioengineered germ (Fig. 1b). Three days after transplantation, the epithelial layer of the bioengineered germ had extended along the guide to the host skin epithelium, and the resulting wound was allowed to heal by maintaining the eruption of the guide, whereas the sample without a guide formed an epithelial cyst (Fig. 1e). At 14 days after the transplantation of the bioengineered germ, with or without the nylon thread into the dermal layer, the eruption and growth of black hair shafts were observed at a frequency of 94% or 38% (n=78 or 8), respectively (Fig. 1e,f). The bioengineered vibrissa follicle germ was also erupted using the inter-epithelial tissue-connecting plastic device at 20.5±6.0 (n=46) days, with a resulting frequency of 74% (n=62; Fig. 1c). However, the bioengineered vibrissae produced unpigmented hairs with a frequency of 95.5% (n=46; Fig. 1f)."
 

nameless

Banned
Reaction score
1,091
This treatment is my strongest hope. I have some other ideas too but Tsuji is my greatest hope. And 2020 is not that far off. 2016 will be over soon. I wish I could safely put myself into cryo sleep until 2020.
 

That Guy

Banned
My Regimen
Reaction score
5,361
2020 is honestly not a long wait. The older you get, the faster time moves. If you are 20 years old right now, 1 year is only 5% of the total time you've lived thus far, so three years is nothing.

That's why a 5 year old waiting to turn 10 feels like an eternity - they have to wait 100% worth of the entire time they've been alive. It's the same when you're 40 waiting to turn 80, it's just that for 40 year olds, 1 year is only 2.5% of your life.
 

whatevr

Senior Member
My Regimen
Reaction score
3,656
It's a race to the finish line (2020).
Hold on to your hairs, last one there's a baldie.
 

hellouser

Senior Member
My Regimen
Reaction score
2,634
It's a race to the finish line (2020).
Hold on to your hairs, last one there's a baldie.

Won't be bald for long though :)
 
Top