end of baldness.they figured it out all.

[2young2retire]

i am sure some capitalistic guys around the globe are this time we speak buying scientists and labs for their mansion backyards.

 

[hairregrowth21]

I'll put up the first $1,000 USD.

 

[hellouser]

You'll need a lab for that which will require about $10,000 worth of equipment. For one person thats a lot but theres many of here so the cost for that will be peanuts. We'd just need to find someone who can perform the procedure!

Someone gave me a negative post rating on this, lol. I'm sure it was a hair transplant surgeon shaking in his boots at the thought of his/her job thrown into complete irrelevance.

 

[I.D WALKER]

As always only time will tell. If it brings you any comfort we all hope you are wrong.

 

[hellouser]

Why is this thread being derailed?

 

[I.D WALKER]

:dunno:

 

[DesperateOne]

2young, take the derma rolling somewhere else, this thread is the biggest thing we had since finasteride. We can not contaminate it with rants about your personal success. Create an account with tumblr or blogpost and put your story there.

 

[Armando Jose]

Prevention before Cure

Controllable production of transplantable adult human high-passage dermal papilla spheroids using 3D Matrigel culture

We have succeeded in culturing human dermal papilla (DP) cells spheroids and developed a three-dimensional Matrigel (basement membrane matrix) culture technique that can enhance and restores DP cells unique characteristics in vitro.

When 10000 DP cells were cultured on the 96 well plates pre-coated with Matrigel for 5 days, both passage 2 and passage 8 DP cells formed spheroidal microtissues with a diameter of 150-250 μm in an aggregative and proliferative manner. We transferred and re-cultured these DP spheroids onto commercial plates. Cells within DP spheres could disaggregate and migrate out, which was similar to primary DP. Moreover, we examined the expression of several genes and proteins associated with hair follicle inductivity of DP cells, such as NCAM, Versican and α-SMA, and confirmed that their expression level was elevated in the spheres compared with the dissociated DP cells. To examine hair-inducing ability of DP spheres, hair germinal matrix cells and DP spheres were mixed and cultured on Matrigel. Unlike the dissociated DP cells and hair germinal matrix cells co-cultured in two dimensions, hair germinal matrix cells can differentiate into hair-like fibers under the induction of the DP spheres made from the high passage cells (passage 8) in vitro.

We are the first to show that passage 3 human hair germinal matrix cells differentiate into hair-like fiber in the presence of human DP spheroids.

These results suggest that three-dimensional Matrigel culture technique is an ideal culture model for forming DP spheroids and that sphere formation partially models the intact DP, resulting in hair induction, even by high passage DP cells.

http://online.liebertpub.com/doi/abs....TEA.2013.0547

so just please do trials in japan fast track we need the cure. thank you. baldness go to hell now

The paper is very interesting but if we want terminal hairs (Thick, long, pigmented, healthy. Lustrous hair) is necessary have a operative sebaceous gland near. or DR's It is more more complex.
Human scalp hair is the more complex system in our body, there are all biological systems, immune, circulatory, hormonal, neuronal, regenerative, …..

• end of baldness.they figured it out all.

The end of baldness will be when we could prevent it,
If any of us has lost his hair’s war, need fight for their offspring, stop or prevent the process is much easier to regain lost hair
Battles will be lost but the victory would be own forever
Prevention better than cure, ….,
To prevent only we need target the initial triggers of the process, only we need know its names, and more, the cure needs the real knowledge of all the process in common hair loss, included the initials.
Then
Prevention better than Cure and, surely also, Prevention before Cure.

 

[karankaran]

But can a cure include something like transplanting each follicle with a genetically resistant follicle? is this technique same as hair multiplication ?

 

[DesperateOne]

What I want know is how are they planning to achieve the hair color we want and is the new follicles suppose to be DHT resistant.

 

[hellouser]

What I want know is how are they planning to achieve the hair color we want

Good question.

and is the new follicles suppose to be DHT resistant.

Only time will tell, but seeing how you can create follicles at will, you can always just go for another procedure and top up. No donor to be used and no scars. I would suspect that the hair will last at least 15-20 years if they weren't DHT resistant (15-20 years of age is typically the absolute earliest any guy will experience hair loss from DHT)

 

[peacemaker]

But can a cure include something like transplanting each follicle with a genetically resistant follicle? is this technique same as hair multiplication ?

I believe this is possible. According to Histogen, they can do such a thing by transplanting hair from the donor area and then regenerating the follicles in the donor area. As long as you activate the wnt pathway to create new follicles either by stimulating complexes or by wounding etc, you will be able to do that.

 

[hellouser]

I believe this is possible. According to Histogen, they can do such a thing by transplanting hair from the donor area and then regenerating the follicles in the donor area. As long as you activate the wnt pathway to create new follicles either by stimulating complexes or by wounding etc, you will be able to do that.

I don't ever recall anything like this being claimed by Histogen. Who told you this or how did you come to believe this? All histogen does is inject a bunch of growth factor proteins, etc. It has nothing to do with regeneration.

 

[2young2retire]

but its you the negative troller rep here. we all know now. we thank you for making it even more clear.

Put your cursor on the red under his name: "peacemaker is considered extremely unhelpful and almost always wrong."

That's what the reputation system of the forum is for.



What does this gibberish even mean? Are you a scientist or a doctor? Do you have any idea of what you're saying?

 

[DesperateOne]

but its you the negative troller rep here. we all know now. we thank you for making it even more clear.

Yes, we know he is the troll, you can go your account and you will see his **** name being the one giving bad rep.

- - - Updated - - -

Personal robots and gene therapy can't come soon enough.

 

[peacemaker]

I don't ever recall anything like this being claimed by Histogen. Who told you this or how did you come to believe this? All histogen does is inject a bunch of growth factor proteins, etc. It has nothing to do with regeneration.

As I repeat myself over and over again, I am not a medical specialist. I am just an avid reader on this subject. Type in "Ziering interview histogen" to Google and listen to the interview. I am sure that you listened to it before, but listen again. Nothing is claimed by Histogen, but they are stating that it IS possible because of the following simplified chain of logical statements:

What does Histogen do? "All histogen does is inject a bunch of growth factor proteins, etc."
--> What does those growth factor proteins do? They activate the wnt pathway (As stated in the interview)
What happens when wnt pathway is activated? --> Stem cells produce hair follicles (Cotsarelis finding)

So using these logical claims that we read all over the hair loss studies, we can extrapolate:

1- What happens when FUE is performed on your head? Hair follicles are moved from your donor area to another area.
2- So what would happen if you inject a bunch of growth factor proteins to your donor area? You would ideally get your follicles back.

Yes, this was something that Histogen believed that could happen (as also stated in the interview). But whether this claim holds true is yet to be seen.

- - - Updated - - -

Put your cursor on the red under his name: "peacemaker is considered extremely unhelpful and almost always wrong."

That's what the reputation system of the forum is for.



What does this gibberish even mean? Are you a scientist or a doctor? Do you have any idea of what you're saying?

I am not going to bother responding to you because you would not even come close to saying me that in real life.

 

[DesperateOne]

Poor hair loss surgeon butchers, I want to know where would they be able to get a job after this comes out. Wouldn't the skills be transferable to butchering at the local super market?

 

[hellouser]

As I repeat myself over and over again, I am not a medical specialist. I am just an avid reader on this subject. Type in "Ziering interview histogen" to Google and listen to the interview. I am sure that you listened to it before, but listen again. Nothing is claimed by Histogen, but they are stating that it IS possible because of the following simplified chain of logical statements:

What does Histogen do? "All histogen does is inject a bunch of growth factor proteins, etc."
--> What does those growth factor proteins do? They activate the wnt pathway (As stated in the interview)
What happens when wnt pathway is activated? --> Stem cells produce hair follicles (Cotsarelis finding)

So using these logical claims that we read all over the hair loss studies, we can extrapolate:

1- What happens when FUE is performed on your head? Hair follicles are moved from your donor area to another area.
2- So what would happen if you inject a bunch of growth factor proteins to your donor area? You would ideally get your follicles back.

Yes, this was something that Histogen believed that could happen (as also stated in the interview). But whether this claim holds true is yet to be seen.

You're making a claim and telling me to go find it? What's wrong with you? SHOW US WHERE HISTOGEN SAID THAT HSC REGENERATES DONOR. Don't tell me to go and try find the info.

In any case, I think you have Histogen mixed up with ACELL.

Also, youre doing an incredible job misleading readers with such false information.

 

[peacemaker]

You're making a claim and telling me to go find it? What's wrong with you? SHOW US WHERE HISTOGEN SAID THAT HSC REGENERATES DONOR. Don't tell me to go and try find the info.

In any case, I think you have Histogen mixed up with ACELL.

Also, youre doing an incredible job misleading readers with such false information.

Dude I just summarized you what Dr. Ziering said in the interview. And gave you a link in case you want to check that out yourself. Nobody knows what any of the future treatments will be able to accomplish in real life. But that claim was made. Period.

 

[hellouser]

Dude I just summarized you what Dr. Ziering said in the interview. And gave you a link in case you want to check that out yourself. Nobody knows what any of the future treatments will be able to accomplish in real life. But that claim was made. Period.

Telling me to google and searching is NOT giving me the link, lol. The claim was NEVER made. *YOU* made it... I wonder why? Will you be in denial if Histogen ever gets released and doesnt show regeneration?

I'll say it for the second time now: Provide us the link/source to where Dr. Ziering said Histogen's HSC will allow regeneration from donor area.