Exploring The Hormonal Route. Hair=life.

[S7E841]

no way so is it entirely possible for me to stop my hairloss if i switch to finasteride????

are you using ru? where do you buy it? do you have results from ru?

 

[S7E841]

Yeah. It’s either we are sensitive to T or some kind of upregulatory effect at the receptor level. Dutasteride has been anecdotally reported to increase frontal thinning by a lot of users.

maybe just doing the oral and topical combo for this problem ... i think the oral and topical combination is much more effective than separately .. and maybe before applying topical dutasteride use dermaroller 0.5mm as stated several times @Experimentality

 

[S7E841]

alright so since om and duta havent worked for me and i been on em 2 years i think i might start e2 after the summer and shave my head for the time being.

before i risk my fertility i SHOULD go to a sperm bank right if i still want to have kids one day? (im only 23) should i quit duta for a month to get my sperm back to normal before doing this?

if i do get on e2... and my hair grows back... and my dick stops working is there a chance that i could have a working sex drive again with my real hair one day?

I don't know what your expectations and your hair situation might be ... but I advise you to go slow with E2. I speak from personal experience .. do not think at all about oral E2 if you are a man and want to continue to feel like one .. if you really want to experiment try estrogel experimenting with low doses and coupled to an AA so that you will not need high doses of E2. this is advice without judging anyone.I don't want to be an expert on the situation .. I don't feel like it at all. but in my opinion it makes no sense to switch from dutasteride to finasteride .. you could make the situation worse by being less powerful in lowering the dht. just my thought

 

[losingbattle88]

maybe just doing the oral and topical combo for this problem ... i think the oral and topical combination is much more effective than separately .. and maybe before applying topical dutasteride use dermaroller 0.5mm as stated several times @Experimentality

Oral and topical duta will raise scalp T even more. I did that for 1.5 years. I did dermaroll once weekly too with duta. But many report systemic sides from topical dutasteride without even needling. It can still infact go systemic. I would not recommend dutasteride it nukes all dht in serum and half of dht and more in the brain depending on dosage.

 

[S7E841]

Oral and topical duta will raise scalp T even more. I did that for 1.5 years. I did dermaroll once weekly too with duta. But many report systemic sides from topical dutasteride without even needling. It can still infact go systemic. I would not recommend dutasteride it nukes all dht in serum and half of dht and more in the brain depending on dosage.

okay .. but I think the important thing is the dht not the testosterone ... and we are not talking about whether it becomes systemic or not, but about efficacy in therapy. side effects aside I think finasteride or dutasteride should be coupled to a stronger AA, see spironolactone-cyproterone-bicalutamide. otherwise I find it hard to win or draw the battle. I always speak from personal experience do not get me wrong .. then luckily each one is different from the other and maybe just dutasteride can be enough for him

 

[losingbattle88]

okay .. but I think the important thing is the dht not the testosterone ... and we are not talking about whether it becomes systemic or not, but about efficacy in therapy. side effects aside I think finasteride or dutasteride should be coupled to a stronger AA, see spironolactone-cyproterone-bicalutamide. otherwise I find it hard to win or draw the battle. I always speak from personal experience do not get me wrong .. then luckily each one is different from the other and maybe just dutasteride can be enough for him

okay .. but I think the important thing is the dht not the testosterone ... and we are not talking about whether it becomes systemic or not, but about efficacy in therapy. side effects aside I think finasteride or dutasteride should be coupled to a stronger AA, see spironolactone-cyproterone-bicalutamide. otherwise I find it hard to win or draw the battle. I always speak from personal experience do not get me wrong .. then luckily each one is different from the other and maybe just dutasteride can be enough for him

DHT ofc is more important but balance is key here. Dutasteride isnt even fda approved for hairloss. Finasteride by itself blocks 70% of serum dht and dutasteride 90%. Its only a 20% difference. Yet dutasteride raise scalp T by 100 and 200%, while finasteride only by 23-24%. T is the weaker androgen but still can shrink hair. We are sensitive to androgens not just DHT.

 

[Mr. Slap Head]

DHT ofc is more important but balance is key here. Dutasteride isnt even fda approved for hairloss. Finasteride by itself blocks 70% of serum dht and dutasteride 90%. Its only a 20% difference. Yet dutasteride raise scalp T by 100 and 200%, while finasteride only by 23-24%. T is the weaker androgen but still can shrink hair. We are sensitive to androgens not just DHT.

Also let’s point out that both drugs reduce scalp DHT similarly, finasteride iirc is about 40-50% and dutasteride is around 50-60%. So not really worth nuking serum DHT for a mere 10% more scalp DHT reduction.

 

[losingbattle88]

Also let’s point out that both drugs reduce scalp DHT similarly, finasteride iirc is about 40-50% and dutasteride is around 50-60%. So not really worth nuking serum DHT for a mere 10% more scalp DHT reduction.

Exactly. I was gonna add that just now lol. finasteride 1mg reduce scalp T by 40% while 0.5mg duta blocks it by 50%. At least a 10% difference in scalp dht. Duta isnt worth it for most people.

 

[Mr. Slap Head]

Exactly. I was gonna add that just now lol. finasteride 1mg reduce scalp T by 40% while 0.5mg duta blocks it by 50%. At least a 10% difference in scalp dht. Duta isnt worth it for most people.

Yeah unless someone is suicidal about hair, just stick with finasteride. Or even minoxidil monotherapy tbh if your hair loss is minor.

 

[keepcoolmybabies]

Are you Jewish?

I'm not, why?

 

[losingbattle88]

Mr slaphead think ur cute too we both do

 

[Adri23]

I don't know what your expectations and your hair situation might be ... but I advise you to go slow with E2. I speak from personal experience .. do not think at all about oral E2 if you are a man and want to continue to feel like one .. if you really want to experiment try estrogel experimenting with low doses and coupled to an AA so that you will not need high doses of E2. this is advice without judging anyone.I don't want to be an expert on the situation .. I don't feel like it at all. but in my opinion it makes no sense to switch from dutasteride to finasteride .. you could make the situation worse by being less powerful in lowering the dht. just my thought

Topicals AA don't do anything for someone with agressive hair loss. Using e2 and bica for almost 2 month not even reduce in shedding.

 

[Mr. Slap Head]

Mr slaphead think ur cute too we both do

Nah brah that’s all you lmao

Topicals AA don't do anything for someone with agressive hair loss. Using e2 and bica for almost 2 month not even reduce in shedding.

well the problem is that E2 topical is basically the same thing as taking it orally since it’s molecular mass is so small it quickly absorbs into the serums. Same with topical finasteride. But you would need quite the dose of E2 to really affect hair which is also the problem. Bica seems to have a pretty favorable molecular mass, but might not work well due to solubility/carrier issues

 

[losingbattle88]

Topicals AA don't do anything for someone with agressive hair loss. Using e2 and bica for almost 2 month not even reduce in shedding.

Nah brah that’s all you lmao




well the problem is that E2 topical is basically the same thing as taking it orally since it’s molecular mass is so small it quickly absorbs into the serums. Same with topical finasteride. But you would need quite the dose of E2 to really affect hair which is also the problem. Bica seems to have a pretty favorable molecular mass, but might not work well due to solubility/carrier issues

I hope she still got her penis :0

 

[Adri23]

Nah brah that’s all you lmao




well the problem is that E2 topical is basically the same thing as taking it orally since it’s molecular mass is so small it quickly absorbs into the serums. Same with topical finasteride. But you would need quite the dose of E2 to really affect hair which is also the problem. Bica seems to have a pretty favorable molecular mass, but might not work well due to solubility/carrier issues

I'm using 0.15 mg/ml x3 ml e2 three times week now and nothing changes. Tried bica 3 times a week 2mg x 4 ml.. I lost the hope on topicals.

 

[Mr. Slap Head]

I hope she still got her penis :0

ew

 

[losingbattle88]

ew

Shemales be hot, OH MAMA!

 

[Adri23]

Shemales be hot, OH MAMA!

I got a shemale friend, you would love her

 

[keepcoolmybabies]

Trans people can be hot, not really a big deal to acknowledge it

 

[CTD]

Trans people can be hot, not really a big deal to acknowledge it