Exploring The Hormonal Route. Hair=life.

exwhyyou

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I plan to test the RU. I want to buy a powder to use for 3-6 months and switch to testosterone injections. If I go bald, I will go back to estradiol injections.
i don't get why you want to add the testosterone injections. your testosterone will prob come back if you stop the estradiol even with ru+duta if you add additional t you're gonna be so bald
 

Almas_NW0

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i don't get why you want to add the testosterone injections. your testosterone will prob come back if you stop the estradiol even with ru+duta if you add additional t you're gonna be so bald
Testosterone may take a very long time to return, or may not return at all, unless special therapy is used. I will only try to get my own T back if I know I can avoid going bald with it. Otherwise, I risk spending a lot of time and money on an experiment that will fail anyway.
If you use T injections, your own T will not come back.
 

Almas_NW0

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What's your BMI? Estradiol didn't give me any hip growth, but my BMI is 17.6. Could be that you have a BMI in the higher healthy weight? I've seen that if you maintain 18 to 19 BMI you don't get much fat distribution (apart from breast) base on what I see on myself. The only change e2 gave to my body is breast (not much tho) and more waist due to muscle atrophy, but if I hit the gym I could get a lean male physique without problems. 1 year 6 months HRT btw.
My BMI is on the border between normal and underweight, I was very thin. But I am genetically predisposed to gaining fat on my thighs. Many can avoid this side effect
 

Adri23

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My BMI is on the border between normal and underweight, I was very thin. But I am genetically predisposed to gaining fat on my thighs. Many can avoid this side effect
Damn it sucks... I'm lucky my genetics stores almost 0 fat giving me lean body(my butt is suffering from that tho lol).
 

Balengu

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i'm pretty as fck now and i love it
newsflash: girls love this too!

cypionate: 0.275ml every 10 days, 11mg/10days
enanthate: 0.375ml /14 days 15mg/14 days

i always top it off a little extra
15 mg every 2 weeks seems a lot. in fact almas said he was on 15mg but then he moved to 10mg every 2 weeks. could the dosage be the reason that gave you that problem with enanthate ? why did you start on 15 and not on 10 ? had you tried the enanthate 10mg every 2 weeks yet ?
 

Adri23

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After 1 year and 6 months of HRT I conclude I have a short of estrogen insensitivity. My hair is worse than ever and I have very low feminization overall. When I was not using HRT I did a genetic test and it said I had very reduced aromatase activity so I wouldn't be surprise if I have estrogen insensitivity. Even with levels of 450 pg/ml at trough my SHBG does not rise further than 74 nmol/L which is very low in comparison of the estradiol levels.
 

Fvgwnx

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cpa cannot interfere with the work of duta and finasteride? I've been taking blowout and finn for 3 months now. and I don’t see the result, just small colorless hairs of 1 cm.
 

SnortingFinasteride

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After 1 year and 6 months of HRT I conclude I have a short of estrogen insensitivity. My hair is worse than ever and I have very low feminization overall. When I was not using HRT I did a genetic test and it said I had very reduced aromatase activity so I wouldn't be surprise if I have estrogen insensitivity. Even with levels of 450 pg/ml at trough my SHBG does not rise further than 74 nmol/L which is very low in comparison of the estradiol levels.
Maybe your high trough estrogen levels have downregulated the Estrogen Receptors somewhat ?


450 pg/ml is pretty high for a trough level. And googling "Estrogen insensitivity" yields a very, very rare condition (much rarer than Androgen insensitiviy)
 

Adri23

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Maybe your high trough estrogen levels have downregulated the Estrogen Receptors somewhat ?


450 pg/ml is pretty high for a trough level. And googling "Estrogen insensitivity" yields a very, very rare condition (much rarer than Androgen insensitiviy)
No, I lowered my levels to 318 pg/ml still the same .... Also e2 receptors does not downregulate unless you have much higher SHBG than mine cause SHBG is the marker that says to your body your e2 is too high and start to downregulate when high.
 

SnortingFinasteride

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No, I lowered my levels to 318 pg/ml still the same .... Also e2 receptors does not downregulate unless you have much higher SHBG than mine cause SHBG is the marker that says to your body your e2 is too high and start to downregulate when high.
All SHBG does is bind to sex hormones and makes it harder for the body to use them. It doesn't interfere with receptor sensitivity. It also prefers binding to androgens more so than estrogens

Estrogen insensitivity is a syndrome on a genetic level. Meaning you are born with such condition. I think if you had such condition, your bones would be brittle by now.

Check your DHT levels, and if possible DHEA and Androstenedione levels as well. Adrenal androgens could hinder feminisation
 

Adri23

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All SHBG does is bind to sex hormones and makes it harder for the body to use them. It doesn't interfere with receptor sensitivity. It also prefers binding to androgens more so than estrogens

Estrogen insensitivity is a syndrome on a genetic level. Meaning you are born with such condition. I think if you had such condition, your bones would be brittle by now.

Check your DHT levels, and if possible DHEA and Androstenedione levels as well. Adrenal androgens could hinder feminisation
This: https://www.ncbi.nlm.nih.gov/pmc/ar...ristics, and exhibit progressive virilization.

My blood test:

Total T: 26 ng/dl.
Free T: 1.6 pg/ml.
DHT: 4,98 ng/dl.
3a diol G: 0.52 ng/ml.
Androstenodione: 110 ng/dl.
E2: 388.1 pg/ml.
Estrone: 138. pg/ml.
SHBG: 85.5 nmol/L.
FSH: <0.30 mUI/ml.
LH: 0.39 mUI/ml.
DHEA: 2.48 ng/mL.
DHEA-S: 219.7 µg/dL.
Prolactin: 13.1 ng/ml.
PSA: 0.040 ng/ml.
Somatomedin C(IGF-1): 180 ng/ml
 

SnortingFinasteride

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Doesn't say anything about high SHBG downregulating the estrongen receptors. And your SHBG isn't high to be fair, seems quite consistent with cis females

In any case, your hormonal profile looks to be in range with cis women.

looking at your regimen, you may need to up the Bicalutamide dosage to 50mg everyday
 

Adri23

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Doesn't say anything about high SHBG downregulating the estrongen receptors. And your SHBG isn't high to be fair, seems quite consistent with cis females

In any case, your hormonal profile looks to be in range with cis women.

looking at your regimen, you may need to up the Bicalutamide dosage to 50mg everyday
The thing is, I used to use bica 25 mg daily which is enough for my body with that blood test but even that didn't improve my hair a tiny bit.
 

Adri23

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How long did you give it before judging that it has no effect ?
9 months.

First pic was my hair on april (10 months hrt) and the second pic is today (1 year 6 months hrt)

The blood test for the first pic was:

Total T: 25 mg/dl
Free T: 1.7 pg/ml
DHT: 6.42 ng/dl
3a diol G: 0.42 ng/ml
Estradiol: 278.5 pg/ml
SHBG: 61 nmol/L
FSH: <0.30 mUI/ml
LH: 0.15 mUI/ml
DHEA-S: 220.1 μg/dl
Prolactin: 33 ng/ml
PSA: 0.08 ng/ml
 

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