I think Estrogen insensitivity doesn't have much to do with how much e2 you have or how much it is lowering T but how much it affects the receptors. Like my body stopped E since there is a primary hormone in more quantity so it stopped to produce endogenous hormones but when E2 reach my estrogen receptors it doesn't biologically do much because my estrogen receptors do not work good.
Exploring The Hormonal Route. Hair=life.
- Thread starter bridgeburn
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The fact that E2 is suppressing your T levels, means that it is actively binding to your Estrogen receptors and exerting its estrogenic effects. Which leads me to believe that your e2 receptors are at least not damaged when it comes to T suppression
Exactly, that is what I meant, prolly my e2 receptors are not entirely fucked up but it has very little biological effects apart from T suppression.
I will probably lower my dosage to 5 mg (I'm on 5.5 mg Een injection weekly). I might aim for 250 pg/ml which is the minimum for T suppression. When my hair was improving my trough levels were at 278 pg/ml despite of bit higher DHT than now, so maybe 300+ pg/ml e2 is not that good at least for my hair, who knows.
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My theory is for those that anti-androgens don’t work, your stem cells in each follicle are clocked to expire early in life - has anyone tried the stem cell therapies in a bottle on the market? Just a gimmick? Some better than others?
For those that AA’s do work, you still lose hair as you age, for the same stem cell reason. Just as your skin, bones, organs continue to age each minute of every day.
For those that AA’s do work, you still lose hair as you age, for the same stem cell reason. Just as your skin, bones, organs continue to age each minute of every day.
Makes sense. My hair is graying a lot in the past months too
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How old are you and is your stomach protruding? How long do your blood relatives normally live to?
I'm 24 and Im underweight with a BMI of 17.5 so my stomach is flat. About my blood relatives it depends. My grandmother from mother side died at 72 from heart dissease while my grandfather is still alive and he is 93. My grandfather from father side died at 73 from cancer while my grandmother from father side is still alive and she is 81.
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Put on some weight if possible. It might reignite some aromatase enzymes
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So it sounds like the only premature aging/stem cell death, is happening on the scalp. Question is what does it mean and what is the remedy? This beats me but all the best in 2024!
And you never know:
Yeah I need to put some weight but it is extremly hard because I have a very fat metabolisim. It is true that my hair was the best when I had a BMI of 19.1
Yeah rest of the body is not showing premature aging, just some minor expresion lines on the corner of mouth but nothin alarming. I will need to find out what is happening. I might be getting a scalp biopsy this year.
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Has HRT helped you before? Why did she stop doing this, what preceded it?
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In the first year of HRT I used high doses of E, and now I can go 3 weeks without injections, but it does not harm my hair.
I'm going to order RU, testosterone injections and try to get off HRT. RU is giving promising results to people on this forum.
It will really suck if RU will not help, and when I go back on estradiol, it stops working.
I'm going to order RU, testosterone injections and try to get off HRT. RU is giving promising results to people on this forum.
It will really suck if RU will not help, and when I go back on estradiol, it stops working.
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Why do you care about his sexual orientation ? He ain't fûking you lmao
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Yes you bald fa99ot
I've been on HRT for 1 year and 7 months. The first 7 months I was on sublingual pills, CPA and dutas and my hair was very bad.
Then I switched to bica + Injections + keep the dutas an my hair started to improve slowly. My peak of hair on this regimen was from april to june. Then I had some major stressor for 5 months + Covid in june + I increased the Eatradiol dosage which lead to a massive shedding. Now I'm left with bad density all over my head and the most important, very very sh*t texture that I can't fix with anything. It has been 7 months since I got covid and 2 months since I have no anxiety but my hair gets worse every month.
Be careful with T. Hope RU is enough for you!
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J parle aussi de français, t pas quelqu'un special . And I can talk 3 more languages if you want mdr
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Pq mdr ? T'es interessé ?