Yeah I don't really know too much about it's tissue selectivity, I'd just assumed the high gyno risk was a result of the 2 fold increase in T and that other NSAA's like Daro and Enza must also be just as risky if not more gyno wise.
Daro and Enza have no positive HPTA axis from my knowledge, but Bicalutamide does and yes you made a great point there. More test = more e.
I feel the same...
wat?
He used Bicalutamide, increased the dosage to 150mg, but continued to go bald. He doesn't write anything else
Everything in "My Regimen" plus Isotretinoin 60mg, come to the end of my CPA journey now and so have started to gradually reduce my dose.
It should help with the appearance of hair loss. We just aren't certain how, in terms of awakening dormant hair versus extending the anagen phase which can present like hair "regrowth".
Yeah, maybe bica is different but spironolactone made me weak and fatigued and I sweated all of the time which only provoked more so it's Nacl depleting mechanism. I used to sleep with a salt shaker on my night table cause I would wake up in the middle of the night wanting salt. I couldn't start the lawn mower or mow for more than five minutes if I managed to. I had to take elevators and I never used to. Peanut butter jars became my nemeses in terms of not being able to open them or soda bottles at times. Weak as a kitten....
That's great that you are testing. Keep those levels in mind because it might be that once you hit a certain threshold, that hair growth really accelerates. People want to know if recoveries are possible without becoming chemically female like @bridgeburn and me and probably Gergely and some others. I just didn't find being stuck in the middle in terms of E2 and T to provide much oomph in terms of hair recovery. I did see improvement more than new hair, I would say and even improvement in sheen or manageability or ability to grow it long is something that only HRT provides really although min/finasteride might do so in smaller and less noticeable ways.
I agree. Twice in my life, androgens made me essentially age gravely all but overnight. In excess, they are poison. Most MtF's are not battling endocrine disorders but some of us are and it is clear from my pics that I am about a thousand times more well and substantially younger looking even apart from my descending hairline. I have much less of a fixation in terms of relentlessly pursuing goals which makes it pleasurable now, instead of feeling driven. I also take ADHD meds and the driven feeling of androgens is a lot like Adderall but even worse for some of us. I would never go back to the apt-to be compulsive "male" state. It would be crazy to do so at my age because of all of the residual health benefits and tissue re-matrixing. Everything but bone is shiny and new. It's amazing and I only think that it works indefinitely going in this direction of MtF in terms of hormones used.
I appreciate the feedback. Although I have nothing against people who transition MtF or visa versa I would like to stay a cis male. You think only 1mg with .75mg estrogel is enough to get into female target ranges? I’m ultimately trying to avoid feminizing as I am already considered a “pretty boy”. I would also like to keep my male sexual function as it’s becoming more important to me (might have a girlfriend soon)
I would have to look but there was a recent study that 2 mg oral is enough to re-set the axis and achieve adult female (approximately of 26 years old) levels of E2 and T but it can take a long time. I was on 2.5 mg of Premarin and 200 mg of spironolactone for about two years and I still was not close to target levels. It gets worse though because from the neck down, I looked like a pretty hot female with a bod that many cis-females would want. So the feminization comes first below the neck at even middling amounts of estrogen. Facial feminization and hair regrowth mostly only came once I flooded my system with first trimester pregnancy levels of E2 at ~2,600 pg/ml and only 9 ng/ml of testosterone. Even at that low level, dermatitis still comes up with my largely vellus beard hair follicles.
Please test your DHEA-S, Androsterone/Pregnane-...-dione
All of those meds are good for hair in one way or the other. Estradiol alone or estadiol with either spironolactone or cyproterone acetate are common simple MtF protocols. If you get your estrogen levels up, hair seems to improve but there's a debate more so about regrowth. In cases where follicles are dormant, it takes a lot to "wake them up" and adult female levels of estradiol and testosterone might be indicated in those situation.