Um.... Yes we do take Avodart and Finasteride many of us, and the consensus is that MtF hair is not fully protected without dutasteride. I currently use dutasteride and I used to use both it and finasteride for several years but desisted because it appeared to be overkill. My conjecture was that reductase inhibitors should be unnecessary without testosterone but the reality is that DHT is incredibly persistent even in some castrates and post-surgical MtF's.
Back/frontdoor -pathway :thumbs_up:
Your knowledge of all of this without having actually passed through all of this yet chemically is startling.
Thanks, I guess? Haha
perhaps IGF1 is somehow related to DHT.
Perhaps but there are limits to my knowledge in terms of putting together some grand theory of baldness via conjecture as opposed to what works. I mean according to the murcine testing DHT should be giving all humans huge beards and huge amounts of head and body hair and it does not so for some reason, we are all largely "naked" apes and males and females parallel each other in total hair volume if you will. It's just located in different places for males, and male body hair lamentably perhaps to many, is just out of style. Well, except for FtM's, Goddess bless them.
Well, thank you. I woke up one day during the quarantine and realized that I had had virtually every baldness experience, male and female and since the science interests me so, I hope that I am able to help some folks diminish the pain of hair loss. I will never forget the night before my 20th birthday and someone telling me that "I was looking a little thin on top" and yes, part of my experience is the father in his 80's with perfect hair so I never saw it coming. I felt sick and I knew that my life would never be the same. I got lucky with polysorbates and then just had a so-so transplant but great maintenance with finasteride/duta/min and then it just stopped working. That sick feeling while I looked in the hand mirror that last night of my being 19 years old will never quite go away....
IFG-1 increases AR sensitivity. Be careful what you wish for...
I also started to lose my hair very early. I have been taking HRT for 2 years. I can't imagine what we would do without E.
Oh, wow! How was it? Whats your current hair like??
Now everything is ok. the last half of the year I have not taken anything. after half a year, the hair became a little worse. now I'm back in HRT mode. but without avodart. I hope all be fine.
Well, stick with this thread and I encourage folks to read about the first 150 to 200 pages while @bridgeburn was still participating because he treats all aspects of the experience and what he writes about HRT is about 99 percent dead on and the rest is because new studies have come out since.
It's not that you won't be fine without duta/finasteride. It's more so like belt and suspenders because it is hard to lose back any gains that we make. Theoretically and scientifically, RI's probably are overkill but we the balding tend to be obsessed with closing all ports to DHT....
then it makes sense to take cyproterone spironolactone and avadart. especially since cyproterone and spironolactoate suppress different hormones
taking dutasteride with cyproterone acetate is not a recommended combo.
try super low doses of E and taper up slowly if you need to. I have been on 1mg Estradiol and .75mg estrogel for 2 months with no feminization and vellus hairs starting to grow. I am in a similar position where I dont want to feminize