Hello everyone About four months on HRT, I thought for a long time but still decided to try this mode for hair growth. I take 4 mg of estradiol valerate sublingually, there is a suspicion that this gives me high levels of estrone, so I'm going to switch to estradiol hemihydrate, also sublingually. Of the drugs available to me, I have FEMOSTON, this drug contains 14 tablets of 2 mg of estradiol and 14 tablets of 2 mg of estradiol/10 mg of didrogesterone. If anyone has experience using this combination drug, write how best to take it? Or is it better to throw out didrogesterone and take pure estradiol hemihydrate? From what I learned: Didrogesterone has a molecular structure similar to that of natural progesterone, but with significantly more pronounced bioavailability compared to progesterone. Didrogesterone differs from other progestogens in that it does not show affinity for androgen, estrogenic receptors, respectively, it does not show estrogenic, androgenic activity. I write through a translator.