Exploring The Hormonal Route. Hair=life.

[Pls_NW-1]

nonbinary HRT

nonbinary HRT Investigating possibilities for nonbinary / femboy / transfem HRT. Trans forums mostly say "you can't pick and choose". I won’t accept it. Goals body feminization / demasculinization. Use some combo of AA and E/SERM. prevent breast growth. Use SERM or get early surgery. preserve pe...

docs.google.com

@Pls_NW-1
@tato123

This is a document created by Maave. There is a lot of interesting information here. For example, here we can see that his hair started to grow back after 2 months of taking Bicalutamide. This is sad for me because I don't see any changes after 2 months. However, I have increased the dosage to 75mg, so I will wait for changes over the next 4 months.

Thank you! I will check it out later on!

 

[Get my hair back]

Hello everyone About four months on HRT, I thought for a long time but still decided to try this mode for hair growth. I take 4 mg of estradiol valerate sublingually, there is a suspicion that this gives me high levels of estrone, so I'm going to switch to estradiol hemihydrate, also sublingually. Of the drugs available to me, I have FEMOSTON, this drug contains 14 tablets of 2 mg of estradiol and 14 tablets of 2 mg of estradiol/10 mg of didrogesterone. If anyone has experience using this combination drug, write how best to take it? Or is it better to throw out didrogesterone and take pure estradiol hemihydrate? From what I learned: Didrogesterone has a molecular structure similar to that of natural progesterone, but with significantly more pronounced bioavailability compared to progesterone. Didrogesterone differs from other progestogens in that it does not show affinity for androgen, estrogenic receptors, respectively, it does not show estrogenic, androgenic activity. I write through a translator.

 

[Almas]

Hello everyone About four months on HRT, I thought for a long time but still decided to try this mode for hair growth. I take 4 mg of estradiol valerate sublingually, there is a suspicion that this gives me high levels of estrone, so I'm going to switch to estradiol hemihydrate, also sublingually. Of the drugs available to me, I have FEMOSTON, this drug contains 14 tablets of 2 mg of estradiol and 14 tablets of 2 mg of estradiol/10 mg of didrogesterone. If anyone has experience using this combination drug, write how best to take it? Or is it better to throw out didrogesterone and take pure estradiol hemihydrate? From what I learned: Didrogesterone has a molecular structure similar to that of natural progesterone, but with significantly more pronounced bioavailability compared to progesterone. Didrogesterone differs from other progestogens in that it does not show affinity for androgen, estrogenic receptors, respectively, it does not show estrogenic, androgenic activity. I write through a translator.

Русский шо ли?)

 

[Hair We Go Go]

Welp, wanted to ask you how you're doing haha

Hello I'm ok, but hair temples still $h1t

I've now thrown in the towel with hair recovery,
Ive spent enough time & money waiting for something to happen in this area ...after trying literally everything.
I recovered my crown in 2018/19 with just finasteride (which was awesome),
but the temples are just too temperamental. I'm fed up with gaining and losing hair there all the time (I no longer have the patience), so I'm getting a hair transplant in June.
June is probably too soon as I had FFS a month ago - so I had my face peeled away (hairline advance) meaning the blood supply to the scalp may not be optimal rn but I'm doing it anyway.

 

[Pls_NW-1]

Hello I'm ok, but hair temples still $h1t

I've now thrown in the towel with hair recovery,
Ive spent enough time & money waiting for something to happen in this area ...after trying literally everything.
I recovered my crown in 2018/19 with just finasteride (which was awesome),
but the temples are just too temperamental. I'm fed up with gaining and losing hair there all the time (I no longer have the patience), so I'm getting a hair transplant in June.
June is probably too soon as I had FFS a month ago - so I had my face peeled away (hairline advance) meaning the blood supply to the scalp may not be optimal rn but I'm doing it anyway.

Crazy! Are you cis-male? Cis-female? Transitioning or non-binary!? Sorry for the personal question, I like your post history.

 

[Hair We Go Go]

Crazy! Are you cis-male? Cis-female? Transitioning or non-binary!? Sorry for the personal question, I like your post history.

Although I recovered the crown, I'm still rocking a ginger comb over and I can't live like this.

 

[Almas]

Increased DHEAS and Decreased Total Testosterone Serum Levels in a Subset of Men with Early-Onset Androgenetic Alopecia: Does a Male PCOS-Equivalent Exist? - PMC

Increased dehydroepiandrosterone sulfate (DHEAS) levels have been reported in men with early-onset (<35 years) androgenetic alopecia (Androgenetic Alopecia). It has been suggested that a male polycystic ovarian syndrome- (PCOS-) equivalent, defined as an endocrine ...

www.ncbi.nlm.nih.gov

 

[Almas]

Serum elevation of dehydroepiandrosterone sulfate associated with male pattern baldness in young men

Eighteen men aged 18 to 32 with rapidly progressive male pattern baldness had serum dehydroepiandrosterone sulfate and testosterone measured. Dehydroe…

www.sciencedirect.com

 

[Pls_NW-1]

Increased DHEAS and Decreased Total Testosterone Serum Levels in a Subset of Men with Early-Onset Androgenetic Alopecia: Does a Male PCOS-Equivalent Exist? - PMC

Increased dehydroepiandrosterone sulfate (DHEAS) levels have been reported in men with early-onset (<35 years) androgenetic alopecia (Androgenetic Alopecia). It has been suggested that a male polycystic ovarian syndrome- (PCOS-) equivalent, defined as an endocrine ...

www.ncbi.nlm.nih.gov

This sounds like my case... crazy.

 

[Almas]

This sounds like my case... crazy.

I can't figure out what DHEA is and how it works. Apparently, it is increased in people with early baldness. Perhaps mine too. Can't do anything about it?
And why can't Bicalutamide handle it? It blocks any androgens, who cares where they come from
I have early puberty, chronic acne - these are also signs of increased DHEA-S. Bicalutamide, as I understand it, should block this sh*t.

 

[Hair We Go Go]

DHEA features top right of this pathways diagram.
I'm not sure what you'd need to block it's conversion, but with Bica blocking the AR you'd have thought you'd be ok? Idk?

Apparently dexamethasone can reduce dhea/dhea-s

But it's probably not a good time to suppress your immune system.

... I'm going to quit posting here again, as I've failed. I shouldn't really offer any advice.

 

[Pls_NW-1]

I alreaey commented this past month. It's hard to control adrenal androgens. And my DHEA-S is sky-high. I started balding with the age of 12/13. I can't remember having thick hair or a juvenile hair line.

 

[Pls_NW-1]

I don't know what to do.

 

[Almas]

I alreaey commented this past month. It's hard to control adrenal androgens. And my DHEA-S is sky-high. I started balding with the age of 12/13. I can't remember having thick hair or a juvenile hair line.

Bicalutamide should block all androgens, shouldn't it?

 

[Pls_NW-1]

Bicalutamide should block all androgens, shouldn't it?

It should. But if the "new androgens", formed from DHEA-S in the follicle, are too many, Bicalutamide can't deal with them.

 

[Hair We Go Go]

Bica is weak vs DHT & AR. It only works by building up and being present in a greater volume.
Or something like that...

 

[Hair We Go Go]

I'm going to delete my last few posts now.
I was really just popping in to say hi.

 

[Pls_NW-1]

Really, dunno what I should do.

 

[Pls_NW-1]

Bica is weak vs DHT & AR. It only works by building up and being present in a greater volume.
Or something like that...

Correct.

 

[Almas]

Really, dunno what I should do.

We don't know anything. Therefore, all we can do is try Bicalutamide and hope it does what we want. We still have no other options. Otherwise, you will have to use HRT, it should help, even if you have a problem with DHEA ...