Finasteride losing effectiveness after 17 months, building up tolerance or what? (Blood Tests)

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GRme11

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Adri23 said:
Just to ask. Why wouldn't you try oral now that nothing is working? Are you scare of side effects?
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I can’t get it easily. Needs the prescription. And yeah, I am kinda scared the side effects, but I wouldn’t say no to try. So, only tretinoin can help a bit for boost.
 
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GRme11

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@Adri23
Trichotest results (to confirm the accuracy of the test, I was done it while I was into the treatments for 2+years. Everything correlates perfectly)

PGD2: Mildly Elevated
SULT1A1: Response to Minoxidil: Positive
5AR1: Activity Normal
5AR2: Mildly Elevated
Aromatase Activity: Mildly Reduced
IGF-1 Activity: Mildly Reduced
ACE Acitivity: Mildly Elevated (More Vasoconstriction-Vasodilation Needed: Arginine, Carnitine, etc.)
CRABP2: Mildly Reduced (Vitamin A not properly absorbed into the cells. Noteworthy: Vitamin A was in the low-end levels when I checked it before the test.)
PTGFR-1,-2,-3: 1,3: Mildly Reduced->Latanoprost can act-2: Negative Response to Latanoprost. So, here it's a bit of a mix.
 
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Adri23

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GRme11 said:
I

I can’t get it easily. Needs the prescription. And yeah, I am kinda scared the side effects, but I wouldn’t say no to try. So, only tretinoin can help a bit for boost.
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Yeah you can try to add tretinoin. I use oral minoxidil and I didnt have any side effect in a dosages from 2.5-4 mg a day, but if go up it to 5mg I start to get tachicardia. I'll try to up it to 5mg again to see what happens.
 
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Adri23

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GRme11 said:
@Adri23
Trichotest results (to confirm the accuracy of the test, I was done it while I was into the treatments for 2+years. Everything correlates perfectly)

PGD2: Mildly Elevated
SULT1A1: Response to Minoxidil: Positive
5AR1: Activity Normal
5AR2: Mildly Elevated
Aromatase Activity: Mildly Reduced
IGF-1 Activity: Mildly Reduced
ACE Acitivity: Mildly Elevated (More Vasoconstriction-Vasodilation Needed: Arginine, Carnitine, etc.)
CRABP2: Mildly Reduced (Vitamin A not properly absorbed into the cells. Noteworthy: Vitamin A was in the low-end levels when I checked it before the test.)
PTGFR-1,-2,-3: 1,3: Mildly Reduced->Latanoprost can act-2: Negative Response to Latanoprost. So, here it's a bit of a mix.
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Your aromatase is not that bad, you should do fine with 0.05% 17a estradiol, maybe you don't need to up it.
 
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Adri23

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GRme11 said:
@Adri23
Trichotest results (to confirm the accuracy of the test, I was done it while I was into the treatments for 2+years. Everything correlates perfectly)

PGD2: Mildly Elevated
SULT1A1: Response to Minoxidil: Positive
5AR1: Activity Normal
5AR2: Mildly Elevated
Aromatase Activity: Mildly Reduced
IGF-1 Activity: Mildly Reduced
ACE Acitivity: Mildly Elevated (More Vasoconstriction-Vasodilation Needed: Arginine, Carnitine, etc.)
CRABP2: Mildly Reduced (Vitamin A not properly absorbed into the cells. Noteworthy: Vitamin A was in the low-end levels when I checked it before the test.)
PTGFR-1,-2,-3: 1,3: Mildly Reduced->Latanoprost can act-2: Negative Response to Latanoprost. So, here it's a bit of a mix.
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I start to think ACE is what gives me scalp aches. I got it on red color and it is a vasoconstrictor, so my scalp aches could be due to low blood flow maybe? It gets kinda better when I massage my scalp for 5-10 min.
 
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Adri23 said:
Can you use corticosteroids for a whole year? I know my hair loss is due to androgenetic alopecia so corticosteroids are only gonna help with scalp aches, so I don't know if 1 year would be necessary.
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I ve used them for longer than that as a precaution.Sometimes i was getting some folliculitis,but that's it. The interesting part is that that i grew more hair than i ve had at baseline(pre-alopecia areata) but sadly i went back to baseline after a few months.
 
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Adri23

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I ve used them for longer than that as a precaution.Sometimes i was getting some folliculitis,but that's it. The interesting part is that that i grew more hair than i ve had at baseline(pre-alopecia areata) but sadly i went back to baseline after a few months.
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That's unfortunate...... What will you do to treat it? Are you gonna start clobetasol again?
 
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Adri23 said:
That's unfortunate...... What will you do to treat it? Are you gonna start clobetasol again?
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No,i am fine now.I meant that clobetasol will give you more hair than you ever had.Thankfully i had AA only once,some people get it again and again
 
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Adri23

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No,i am fine now.I meant that clobetasol will give you more hair than you ever had.Thankfully i had AA only once,some people get it again and again
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But I do not have Alopecia Areata, so I don't think it will regrow any hair to be honest. I've used it in the past for my seborrheic dermatitis.
 
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GRme11

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@Adri23 @Mr. Slap Head @losingbattle88 @DoctorHouse

Well, I got most of my results back from the blood tests (different lab this time). DHT, 3a-Diol-G, and PSA levels are not ready yet. I'm waiting for them. I want to say, guys, that my blood tests are not good. I was shocked by the results. Especially from my CBC and my Bilirubin levels, both total, direct and indirect. I can see why my hair is taking a hit, too, despite the classic male pattern baldness-DUPA that I have already. Not to mention my hormones. I will be laughing my *** off if DHT comes back normal/normal-high or even the 3a-Diol-G with these hormones. No surprise here. We saw plenty of these cases here. I made a lot of sacrifices just to live, and what? To have some hair on my head for a sixteen years old boy! Nothing abnormal! My mental health declined. My body is now deteriorating. Who knows what I have now. I've always feared the most gyno and my liver function from the side effects. Screw the libido and such! I said it before here, and I will say it again. I hate these ANDROGENS AND MY f*****g GENES, which destroyed me so early in my life. Which destroyed my mental health and my psychology as a person. Giving away my sexual function/libido was the easiest side effect I could trade it off. I said it here. I just wanted to feel good with myself, my family, and my friends, that's all. Nothing more, nothing less. I feel so exhausted from this non-stop battle. It's already six years, and two years, I am seeking and reading everything for this. All my soul sucked from this curse! I could tell so much more, but I won't. That's all for now. The aftermath, I don't know it, like all of us.
 
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Adri23

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GRme11 said:
@Adri23 @Mr. Slap Head @losingbattle88 @DoctorHouse

Well, I got most of my results back from the blood tests (different lab this time). DHT, 3a-Diol-G, and PSA levels are not ready yet. I'm waiting for them. I want to say, guys, that my blood tests are not good. I was shocked by the results. Especially from my CBC and my Bilirubin levels, both total, direct and indirect. I can see why my hair is taking a hit, too, despite the classic male pattern baldness-DUPA that I have already. Not to mention my hormones. I will be laughing my *** off if DHT comes back normal/normal-high or even the 3a-Diol-G with these hormones. No surprise here. We saw plenty of these cases here. I made a lot of sacrifices just to live, and what? To have some hair on my head for a sixteen years old boy! Nothing abnormal! My mental health declined. My body is now deteriorating. Who knows what I have now. I've always feared the most gyno and my liver function from the side effects. Screw the libido and such! I said it before here, and I will say it again. I hate these ANDROGENS AND MY f*****g GENES, which destroyed me so early in my life. Which destroyed my mental health and my psychology as a person. Giving away my sexual function/libido was the easiest side effect I could trade it off. I said it here. I just wanted to feel good with myself, my family, and my friends, that's all. Nothing more, nothing less. I feel so exhausted from this non-stop battle. It's already six years, and two years, I am seeking and reading everything for this. All my soul sucked from this curse! I could tell so much more, but I won't. That's all for now. The aftermath, I don't know it, like all of us.
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I feel you... Everyone that fights this sh*t, risk its health in order to maintain the mental health. We end up with a deteriorated physical health, psychological issues and a f*****g disgusting hair.... I hope this sh*t works and I don't have to worry about this in a long time, but at this point, I've no hope anymore. Hope you get better bro!
 
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losingbattle88

losingbattle88

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Adri23 said:
I feel you... Everyone that fights this sh*t, risk its health in order to maintain the mental health. We end up with a deteriorated physical health, psychological issues and a f*****g disgusting hair.... I hope this sh*t works and I don't have to worry about this in a long time, but at this point, I've no hope anymore. Hope you get better bro!
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Massages bro massages. Lol
 
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