Nice thread, i read your post on tressless very instructive !
So my question is : What is the best treatment for baldness for a cis-male who don’t mind a slight gyno but who wants his dick to work fine ?
With Bica, it can be beneficial but it might depend upon your E2 and T1 levels whether you need it or not. Basically everyone agrees that it shouldn't be taken long-term without E2. You could go a couple of months and see if Bica helps but at some point, you will need to desist or add E2. Some transgender providers will prescribe an AA for up to 90 days. I think this is done more often in Europe but also by some in the U.S. The theory is that somehow this resets the system and makes it ready to add E2 for HRT. I have never understood the benefit here. Most MtF's start off with 1 to 4 mg of estradiol swallowed and an AA but I only started off on Premarin and it is probably about fifty-fifty related to whether folks start off with Estradiol only vel non.Yeah topicals helps to prevent feminization since it doesn’t go systemic (partially) but it’s really a hassle. I prefer oral drugs haha
Btw, i’m thinking of 50mg of bicalutamide once a week since it has a pretty long half-life. Can it benefits my overall hair ? I saw study that it doesn’t affect the penis lengths and others things related to that.
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Date | 12/24/2020 02:51 PM |
Summary | Lab Report: CMP14+eGFR, CBC With Differential/Platelet, Lipid Panel, Tes ... |
Location | Chase Brexton Health Care - Mount Vernon Center |
Provider | Deborah PA |
Status | Signed |
Doctor Id | 233 |
Patient: Jane Elizabeth ID: 1100 Note: All result statuses are Final unless otherwise noted. Patient Note: PATIENT NOT FASTING Tests: (1) CMP14+eGFR (334943) Glucose 72 mg/dL 65-99 BUN 11 mg/dL 6-24 Creatinine 0.78 mg/dL 0.76-1.27 eGFR If NonAfricn Am 101 mL/min/1.73 >59 eGFR If Africn Am 117 mL/min/1.73 >59 BUN/Creatinine Ratio 14 9-20 Sodium 138 mmol/L 134-144 Potassium 4.5 mmol/L 3.5-5.2 Chloride 104 mmol/L 96-106 Carbon Dioxide, Total 24 mmol/L 20-29 Calcium 8.7 mg/dL 8.7-10.2 Protein, Total 6.1 g/dL 6.0-8.5 Albumin 3.8 g/dL 3.8-4.9 Globulin, Total 2.3 g/dL 1.5-4.5 A/G Ratio 1.7 1.2-2.2 Bilirubin, Total <0.2 mg/dL 0.0-1.2 Alkaline Phosphatase 46 IU/L 39-117 AST (SGOT) 16 IU/L 0-40 ALT (SGPT) 14 IU/L 0-44 Tests: (2) CBC With Differential/Platelet (005009) WBC 10.7 x10E3/uL 3.4-10.8 RBC [L] 3.33 x10E6/uL 4.14-5.80 Hemoglobin [L] 10.9 g/dL 13.0-17.7 Hematocrit [L] 33.0 % 37.5-51.0 MCV [H] 99 fL 79-97 MCH 32.7 pg 26.6-33.0 MCHC 33.0 g/dL 31.5-35.7 RDW 12.3 % 11.6-15.4 Platelets 310 x10E3/uL 150-450 Neutrophils 73 % Not Estab. Lymphs 13 % Not Estab. Monocytes 10 % Not Estab. Eos 3 % Not Estab. Basos 0 % Not Estab. Neutrophils (Absolute) [H] 7.8 x10E3/uL 1.4-7.0 Lymphs (Absolute) 1.4 x10E3/uL 0.7-3.1 Monocytes(Absolute) [H] 1.1 x10E3/uL 0.1-0.9 Eos (Absolute) 0.3 x10E3/uL 0.0-0.4 Baso (Absolute) 0.0 x10E3/uL 0.0-0.2 Immature Granulocytes 1 % Not Estab. Immature Grans (Abs) 0.1 x10E3/uL 0.0-0.1 Tests: (3) Lipid Panel (303756) Cholesterol, Total 160 mg/dL 100-199 Triglycerides 135 mg/dL 0-149 HDL Cholesterol 62 mg/dL >39 VLDL Cholesterol Cal 23 mg/dL 5-40 LDL Chol Calc (NIH) 75 mg/dL 0-99 Tests: (4) Testosterone, Serum (004226) Testosterone, Serum [L] 12 ng/dL 264-916 Adult male reference interval is based on a population of healthy nonobese males (BMI <30) between 19 and 39 years old. Travison, et.al. JCEM 2017,102;1161-1173. PMID: 28324103. Tests: (5) Estradiol (004515) Estradiol [H] 2485.0 pg/mL 7.6-42.6 Roche ECLIA methodology Note: An exclamation mark (!) indicates a result that was not dispersed into the flowsheet. Document Creation Date: 12/25/2020 6:42 AM _______________________________________________________________________ (1) Order result status: Final Collection or observation date-time: 12/24/2020 14:51 Requested date-time: Receipt date-time: 12/24/2020 00:00 Reported date-time: 12/25/2020 06:35 Referring Physician: Ordering Physician: D DUNN (ddunn) Specimen Source: Source: 1100 Filler Order Number: 35949618200 LAB Lab site: Performed At: BN, LabCorp Burlington 1447 York Court Burlington, NC 272153361 Sanjai Nagendra MD Phone: 8007624344 (2) Order result status: Final Collection or observation date-time: 12/24/2020 14:51 Requested date-time: Receipt date-time: 12/24/2020 00:00 Reported date-time: 12/25/2020 06:35 Referring Physician: Ordering Physician: D DUNN (ddunn) Specimen Source: Source: 1100 Filler Order Number: 35949618200 LAB Lab site: Performed At: BN, LabCorp Burlington 1447 York Court Burlington, NC 272153361 Sanjai Nagendra MD Phone: 8007624344 (3) Order result status: Final Collection or observation date-time: 12/24/2020 14:51 Requested date-time: Receipt date-time: 12/24/2020 00:00 Reported date-time: 12/25/2020 06:35 Referring Physician: Ordering Physician: D DUNN (ddunn) Specimen Source: Source: 1100 Filler Order Number: 35949618200 LAB Lab site: Performed At: BN, LabCorp Burlington 1447 York Court Burlington, NC 272153361 Sanjai Nagendra MD Phone: 8007624344 (4) Order result status: Final Collection or observation date-time: 12/24/2020 14:51 Requested date-time: Receipt date-time: 12/24/2020 00:00 Reported date-time: 12/25/2020 06:35 Referring Physician: Ordering Physician: D DUNN (ddunn) Specimen Source: Source: 1100 Filler Order Number: 35949618200 LAB Lab site: Performed At: BN, LabCorp Burlington 1447 York Court Burlington, NC 272153361 Sanjai Nagendra MD Phone: 8007624344 (5) Order result status: Final Collection or observation date-time: 12/24/2020 14:51 Requested date-time: Receipt date-time: 12/24/2020 00:00 Reported date-time: 12/25/2020 06:35 Referring Physician: Ordering Physician: Specimen Source: Source: 1100 Filler Order Number: 35949618200 LAB Lab site: Performed At: BN, LabCorp Burlington 1447 York Court Burlington, NC 272153361 ----------------- The following results differed from their previous value: eGFR If Africn Am Old Value: 101 New Value: 117 ----------------- The following non-numeric lab results were dispersed to the flowsheet even though numeric results were expected: Bilirubin, Total, <0.2 | |
Well, I don't love the terminology used. I prefer "extremely high" but that was the goal to see what unlimited usage of estradiol might bring forth. Many of you who test regularly, I would appreciate any thoughts related to titration downward. I have to say that I have seen some incredibly positive things with my face and hair and part of the point here was to see if "pregnancy" levels of estrogen might help me "unstall" (Dr. Will Powers' term) my facial, chest, hip and hair progress towards further or complete feminization. After seven years, I had to finally push to the finish line.Is it bad that your estrogen level is “toxic” ?
Here's something that I know some of you are either using or thinking about using. There are some pretty impressive pictures. At the same time, I think that I have read that it doesn't work as well as reductase inhibitors:
Thank you. I am going to put together a list of things I have used and then things that might work for others.RU is pretty weak on its own but when combined with fina/duta might just help tip the balance in your favor.
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What kind of poly 80 is for scalp at health stores? This is what goggle says about it:Ranking the Hair Treatments that I have used going back to 1984:
To all the meds I've used before
Who traveled in and out my door
I'm glad they came along
I dedicate this song
To all the meds I've used before
1. Estradiol/Estrogel
2. Oral Minoxidil
3. Dutasteride
4. Finasteride
5. Topical Minoxidil
6. Biestro Topical Cream
7. Medroxyprogesterone Acetate/Provera/Depo-provera/MPA with estrogen regime
8. Addition of spironolactone or other AA to low-dose estradiol, not alone
9. Polysorbate 60
10. Polysorbate 80
11. Microneedling
12. Ketoconozole
13. Retin-A/tretinoin
14. Rob's Massages
15. L-Acetyl Cysteine
16. Saw Palmetto
17 Placental Factors Formulas
18. Biotin
19. Laser Comb
20. Diet based upon phytochemicals and omega 3's
I might have overlooked a couple. Ranking is based upon my own experiences and the literature. Note, some of the above could be synergistic which can account for differences in terms of ranking.
Essentially, treatments 14-20 did nothing one way or the other that I could perceive. It would be great to see others post their own top five or more treatments tried in terms of efficacy. Sorry, Rob, but I love your site otherwise and I read every article. I just think the massages as explained on his site are too rough for anyone worried about catagen. Since I was using spironolactone, derma-rolling and doing the massages, perhaps the three together were too rough. I think spironolactone is good for hair and had I known more about titration, I might have avoided some of the many sides.
Ranking the Hair Treatments that I have used gong back to 1984 in terms of efficacy with no to few sides. If there is a tie, the literature trumps. In my opinion, all of the below should be tried. The first three are the only ones likely to have sides for anyone but they have had zero sides for me. For people opposed to the hormonal route, three through eight have all been helpful to me anecdotally.
1. Dutasteride
2. Finasteride
3. Topical Minoxidil
4. Microneedling
5. Polysorbate 60
6. Polysorbate 80
7. Ketoconozole
8. Retin-A/tretinoin
I haven't seen Polysorbate 60 in a while. Polysorbate 80 can still be found in health food stores. I am fairly certain that Polysorbate 60 can be ordered from a variety of places as it is commonly used as a food preservative. The great thing about Polysorbate 60 is that it works really well as a hair dressing that you leave in. Polysorbate 80 is much, much stickier, almost like honey and should be left in for 5 to 30 minutes and then washed out. You really have no choice unless you sleep with Polysorbate 80 in but you can't style hair until it is rinsed away, which is easier in the tub. Polysorbate 60 all but saved my life and I will always be greatful to Bob Adams and New Generation for coming out and advertising in 1984 with their infomercials. Polysorbate 80 also had infomercials with Robert Vaughn from the Man from Uncle hosting the half hour show touting the Helsinki Formula. Purportedly, it had been discovered in Finland, hence the name.
There was a third prominent infomercial with a product known as Hair in a spray can and boy, was that stuff fantastic. I can no longer locate it and I guess I don't need it anymore. When I had my shed, I looked around and couldn't find it. The stuff was shown in the Fabulous Baker Boys with the brothers Bridges. It worked far better than the messy sprinkle stuff that seems to be all that's left on the market.
This is so interesting. The 80s were awesome (even though I wasn't even born yet lol).Polysorbates:
This article jumped out: https://newhair.com/baldingblog/is-polysorbate-a-hair-loss-treatment/
Polysorbates are used in food and it is interesting to see in the article that one of the people said something similar to me about how sticky polysorbate 80 is. They were sold under the sebum plug theory which was discredited in the 80's and the FDA chased them out of business to "protect" us. I have absolutely nothing behind this except I saw great stabilization in my hair loss from what I had expected. I think that the products were sold in good faith and that they did work for many people. My basis for this is, strangely enough, that the results from the two in terms of regrowth even in the commercials and in still photos were not all the great, similar to minoxidil "regrowth". Bob Murphy still had a comb-over, from New Generation and his results were perhaps cosmetically significant but eh, just barely. He still looked balding. So the fact that we didn't have any great pictures of regrowth worked in favor of these products in my opinion. Even slowing down hair loss in 1984 was the greatest treatment since the Garden of Eden where there was no baldness, apparently.
We just don't know how exactly. For what it's worth, I believe that they act similarly to Keto. They help keep sebum at bay and yeast colonies from overpopulating, perhaps thereby lessening inflammation and reducing hair loss. Inflammation is getting to be sort of a catch-all thing in hair loss. I go back and forth between placebo effect and inflammation-lessening and I think that they did work to slow down hair loss and for some to the point where at least some "growth" was apparent.
I guess I am supposed to be angry for being "snookered" but I don't think that I was. There were independent reports at least from Finland and the U.S. and I assume Canada that they did in fact work to some extent. They were often advertised in men's fitness and work-out magazines. The Polysorbate 60 sounds like what a lot of people are looking for in terms of being a hair dressing that can be left in without being too heavy for styling.
Note that the doctor refusing to to take a stand on them is William Rassman, who, for business, sort of hangs out on Tressless and he is well-respected but I don't know his age because pretty much anyone in college during the 80's would have come across these products, the placental factors products and Hair in a Spray Can because you kept hitting the infomercials all of the time.
I digress but back then, cable had 40 channels at most so you could actually scroll through every channel unlike 700 channels on cable nowadays. In some ways it was better because you would only have channels 2 through 13 in some areas which meant the big four networks, a couple of syndicated networks, CNN and ESPN and one or two slots for HBO which I would love to have back instead of 600 channels full of garbage like now. With HBOMax now out online, I am not sure why anyone would bother with cable except to get ESPN. I had Sony for online cable last year and they went belly up in January of 2020 and I never bothered to get a replacement.
Here is a site devoted to blacks who often have different hair issues with breakage, with this link dating to 2008. Rassman's is from 2012 so they are gradually being forgotten but maybe what is explained here is better than my theory, as they link them to castor oil in terms of working:
PolySorbate 80...
do you still use it? Haven't heard about it in a while....forum.blackhairmedia.com
Also note that the mere everyday or twice a day rubbing of the product in, in itself, might have slight beneficial effects, including minoxidil and Estrogel. And ah, yes, some of this is coming back to me, some versions had biotin and niacin in them.
Here is info about the FDA action: https://about.usps.com/who-we-are/judicial/admin-decisions/1983/11-152dd.htm
Here's an L.A. Times story about both products and the devotion to them. I agree. Until New Generation, I was without hope and I often joke on Tressless, "you know what makes a person unable to get wood? Being bald....": This is an excellent article. If you can't get it, then click on Reader on your browser and it should work:
Splitting Hairs : A Bald Tale of Two Guys, Too Much Testosterone and the U.S. Legal System
THE MOUSE FORMULA The threat was delivered to Hal Z.www.latimes.com
I love this quote: "This whole hair-growth phenomenon needs some context. First, understand that the fate of a human hair from the base of its root to the tip of its shaft presents one of the most complex and baffling systems of the human body. Heart attacks, glandular activity and multiple orgasms have been relatively easy to understand compared to receding hairlines."
And here: https://www.newswire.com/the-original-hair-loss-treatment/201249
This is a turgid study about different Malassezia which might be leaving inflammatory by-products on the scalp: https://www.sciencedirect.com/science/article/pii/S0022202X15335405