Hell yea, brand new update from Stemson!

[MeDK]

Yea creating new hairs from scratch with stem cells is much more complex than just trying to stimulate existing ones. It's borderline science fiction, but also has so much more potential.

how can it have more potential?

It will have the same downfall as normal hair transplants, they can't do normal/high density hair if they where to grow a full follicle and then transplant it. (not that i think that will be the method)

So if already existing hair transplants will thin out, what will make sure that stemsons hair transplant won't? And if we think of their "generic", then my guess is that it won't work. Just like other people who gets organ transplants, they are on immune suppression medication. That will be very expensive and take people in to high risk of dying of normal sicknesses and infections. - If we go with the full grown hair follicles transplanted.

That is why autologous stem cell transplants/injections are so much better, we are beyond all of this mentioned before.

 

[MeDK]

what does replicell have? 100 new hairs in a year? it is not and will never be a solution, and as for Stemson, they will either confirm something within 5 years, or end up like Tsuji, i.e. without an investor and his money, no company will wait for a breakthrough therapy that will take place in 20 years

We still don't know if Replicel have a change of multiple injections to enhance the results. But for now. Replicel are they only ones with "100 new hairs in a year" so its more than all the others who haven't delivered anything.

 

[MeDK]

but it is not a solution that will give any positive cosmetic effect

they are still at phase 2, so they are still working on the right dosages. So we don't know, and can only speculate about it.

But facts are Replicel are still the only ones doing human trails

 

[werefckd]

they are still at phase 2, so they are still working on the right dosages. So we don't know, and can only speculate about it.

But facts are Replicel are still the only ones doing human trails

They are doing human trials for almost half a decade no? Still trying to find the "right" dosage.

I prefer a promising treatment that hasn't done clinical trials yet than a treatment that has done clinical trials and failed.

 

[werefckd]

how can it have more potential?

It will have the same downfall as normal hair transplants, they can't do normal/high density hair if they where to grow a full follicle and then transplant it. (not that i think that will be the method)

So if already existing hair transplants will thin out, what will make sure that stemsons hair transplant won't? And if we think of their "generic", then my guess is that it won't work. Just like other people who gets organ transplants, they are on immune suppression medication. That will be very expensive and take people in to high risk of dying of normal sicknesses and infections. - If we go with the full grown hair follicles transplanted.

That is why autologous stem cell transplants/injections are so much better, we are beyond all of this mentioned before.

It's looking like the Replicel solution barely works at all, so it's not hard to have more potential than that.

For example, Stemson's solution in theory has the potential to make hairs grow in a totally slick bald area. It can also lower and improve your original hairline. It can put hair and fix scar areas.

Nowadays the only real downfall of hair transplants (if you get a good doctor) is lack of donor area. With unlimited hairs you can get back to your native hair density (google dense packing).

And Stemson will use autologous stem cells in the beginning so I don't know why you are worried about organ rejection.

Will it be perfect? No. But the potential is tremendous.

 

[MeDK]

They are doing human trials for almost half a decade no? Still trying to find the "right" dosage.

I prefer a promising treatment that hasn't done clinical trials yet than a treatment that has done clinical trials and failed.

No, then you don't understand have clinical trails work.

Phase 2 is the phase where they find the most effective dosage, and Replicel have only undergone one of those, and it working on a second one.

But yes it have taken them a long time to get to that point, that is how the medical world works. Its a long term development. Its not like a video game where its done within very few years.

But that you prefer treatments that haven't done any scientific evaluation of the treatment, to see if it works and is safe. That is just how that is. Some people just doesn't care about their own bodies.

 

[werefckd]

Covid didn't help I'm sure.

Excuses bro...​

​

Stemson target UK for expansion of research and development – with backing of impact investor Fortunis Capital​

November 10, 2020

Biotech innovator Stemson are scoping out research and development investments in the UK to develop a revolutionary cure for baldness in partnership with London-based Fortunis Capital as their lead investor in the country, it was announced today.
San Diego-based Stemson Therapeutics is developing technology to restore human hair growth with a novel approach using the patient’s own cells to generate new hair follicles.
Funding from impact investor Fortunis will support research and development of the product solution and position the UK as a leading contender to conduct human clinical trials,

Read More »

Stemson Secures $7.5M Seed Financing To Advance Hair Regeneration Therapy For Hair Loss​

September 16, 2020

Stemson Therapeutics announced today a $7.5 million seed financing led by Allergan Aesthetics, an AbbVie Company, and impact investor Fortunis Capital to advance development of Stemson’s therapeutic solution to cure hair loss. Stemson aims to restore human hair growth with a novel approach using the patient’s own cells to generate new hair follicles.
See the press release

Read More »

Stemson’s Cornerstone Patent Approved in US​

September 14, 2020

Stemson Therapeutics announced approval in the United States of US patent No. 10716808, entitled “Methods and compositions to modulate hair growth” licensed exclusively from the Sanford Burnham Prebys Medical Discovery Institute. The patent covers a novel process developed by Stemson co-founder and Chief Scientific Officer, Alexey Terskikh, PhD, to differentiate Induced Pluripotent Stem Cells (iPSC) into dermal papilla cells, the cell type primarily responsible for controlling hair follicle generation and hair cycling. Issuance of this foundational patent provides stability surrounding the company’s efforts to develop its breakthrough iPSC-based solution for hair growth.

Read More »

Stemson Appoints Meghan Samberg, PhD, as Vice President, R&D and Preclinical Development​

September 8, 2020

Stemson Therapeutics is pleased to announce Meghan Samberg, PhD, joined our team as Vice President, R&D and Preclinical Development. Dr. Samberg will lead Stemson’s research and development efforts to prepare for human clinical trials of our hair growth cell therapy and will be responsible for helping drive regulatory and clinical strategy.
“Meghan brings extensive preclinical and clinical research experience and adds depth to the Stemson management team. Her expertise in tissue engineering strategies,

 

[MeDK]

It's looking like the Replicel solution barely works at all, so it's not hard to have more potential than that.

For example, Stemson's solution in theory has the potential to make hairs grow in a totally slick bald area. It can also lower and improve your original hairline. It can put hair and fix scar areas.

Nowadays the only real downfall of hair transplants (if you get a good doctor) is lack of donor area. With unlimited hairs you can get back to your native hair density (google dense packing).

And Stemson will use autologous stem cells in the beginning so I don't know why you are worried about organ rejection.

Will it be perfect? No. But the potential is tremendous.

Many treatments can do a lot of things in theory. Many treatments didn't do anything in real life.

But good luck with the stemson hype train. Seems like you believe a lot in it.

 

[werefckd]

No, then you don't understand have clinical trails work.

Phase 2 is the phase where they find the most effective dosage, and Replicel have only undergone one of those, and it working on a second one.

But yes it have taken them a long time to get to that point, that is how the medical world works. Its a long term development. Its not like a video game where its done within very few years.

But that you prefer treatments that haven't done any scientific evaluation of the treatment, to see if it works and is safe. That is just how that is. Some people just doesn't care about their own bodies.

I wish they succeed tremendously

 

[werefckd]

Many treatments can do a lot of things in theory. Many treatments didn't do anything in real life.

But good luck with the stemson hype train. Seems like you believe a lot in it.

Dr. Terskish is past the speculative state. They published solid papers, founded a company, hired legit researchers, demonstrated real progress, raised money, are expanding.

Still, the odds are stacked against them. I wish them all the luck in the world together with their brains as they will need it.

 

[MeDK]

Dr. Terskish is past the speculative state. They published solid papers, founded a company, hired legit researchers, demonstrated real progress, raised money, are expanding.

Still, the odds are stacked against them. I wish them all the luck in the world together with their brains as they will need it.

They aren't past speculative. Because they STILL HAVE NOT done a proof of concept in humans !

That is the first step for all research considering the real life performance.

They can to many papers over the next 100 years, but they have no weight behind them if they can't translate it into humans. That is why so many others haven't moved on. Because they couldn't translate it into human, many have very good results with mice studies, but it doesn't translate into humans at all. If so, then we would have cured like half of the known diseases today

 

[werefckd]

How did this doom crew go from "we're all screwed" to "Stemson will save us all"? One extreme to the other, both equally misguided.

We're not cheering for anyone here. The discussion started about the technicalities of their approach.

If you read my posts you will see me saying that IF Stemson succeeds (and they probably won't), it will still take many years, will be expensive as f*** and there will be huge waiting lines. Does it sound like fanboyism to you?

Still, all the other horses in this race have bailed out or are basically sh*t IMO, so I think Stemson's research and approach are the most interesting one currently. But really want some effective treatment and new hairs, it come from any company. I'm tired of waiting years or decades and NOTHING new hitting the shelves, that's all.

 

[werefckd]

They aren't past speculative. Because they STILL HAVE NOT done a proof of concept in humans !

That is the first step for all research considering the real life performance.

They can to many papers over the next 100 years, but they have no weight behind them if they can't translate it into humans. That is why so many others haven't moved on. Because they couldn't translate it into human, many have very good results with mice studies, but it doesn't translate into humans at all. If so, then we would have cured like half of the known diseases today

Ok we can argue what "speculative" means forever.

But do you know how hard is to raise $7,5 million dollars for company with no revenues that was just founded a year ago?

I challenge you to list all the new hair treatments companies that have raised that amount of early stage capital. It will be very few, if any. They have something different.

 

[RolfLeeBuckler]

then why do you say they will fall? Have idiots invested $ 7.5 million in Stemson?

Bro hair cloning will never happen! Why you cant accept this?!
Stemson could commercialize in 2050-2060 (Human trials in 2040-2045) Most optimistic scenario!!!

But it is more realistic that Stemson will fail like all other hair cloning projects. Realize that!!

 

[RolfLeeBuckler]

Stemson will be finished in 2025, remember my words, i will be back in 2025 and remind you that

hahaha 2025 you are so stupid. Just wait 5 years and your problems will be solved Do you have your information of folliclethought or youngjet?
In realistic scenaro they will start trials between 2080-2090. Commercialization in 2100 is possible

 

[coolio]

James Dean accidentally got his front teeth knocked out as a kid. He had to wear a bridge in his mouth for the rest of his life (no dental implants back then).

If he had gone bald in his teens, he probably would have slapped on a hairpiece and gotten on with his career.

 

[werefckd]

then why do you say they will fall? Have idiots invested $ 7.5 million in Stemson?

I didn't say they WILL fail, I said they will mostly likely fail/have chances against them.

Their investors are not fools, it's normal for venture capital funds to invest in high risk high return opportunities. For example, they invest in 10 companies and expecting to lose all the money on 5-7 of them while hitting a home run (10-100x returns) in 1-3 of them. The returns on the few companies that succeed are more than enough to offset the losses on the other companies and deliver net gains.

For example: 20% chance of succeeding combined with a 10x (1,000%) return of capital if they succeed gives you a positive mathematic expectancy. Say you invest $1M * 20% * 1,000% the expected value is $ 2M, you double your money.

So even if Stemson will most likely fail (and I agree with MeDK, not having a proof of concept in humans is a b**ch), it doesn't mean it's a sucker bet because if they succeed their value will sky rocket to the moon and deliver crazy returns. And of course if Stemson investors put money on them is because they have seen enough to think they have a fair chance at that.

 

[jan_miezda]

hahaha 2025 you are so stupid. Just wait 5 years and your problems will be solved Do you have your information of folliclethought or youngjet?
In realistic scenaro they will start trials between 2080-2090. Commercialization in 2100 is possible

i think tsuji just used youngjet as a tool to fool everyone and obtain a good public perception of his research

 

[jan_miezda]

Tsuji doesn't give a sh*t on bald and balding guys

I agree, but I do not see that they will have 10 years to research, will the investor wait that long? in my opinion no, so they will end up as organ technologies

It doesn’t even make sense to research for 10 year

 

[werefckd]

I agree, but I do not see that they will have 10 years to research, will the investor wait that long? in my opinion no, so they will end up as organ technologies

Sure, an early investor is expected to wait many years before he can sell, if ever.