How Different Types Of Estrogen Promote (and Hinder) Hair Growth

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Canuto

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John Difool said:
That's exactly what I am looking for. Btw adding Progresterone topical at 10% boosted my hair appearance significantly
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I have progesterone added in my next topical, as I'm low due to TRT.

Did you measure serum levels before and after? I'm curious to see how much of that went systemic.
Dr. Marliani in Italy always praised progesterone as being superior to 5-ar inhibitors.
 
ElToso

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I used for years a lotion with 1% progesterone and 0.05% estrone and since I stopped using it I lost a lot of hair on the temples. I’m going to start using it again soon, but I think I’m going to remove progesterone and increase estrone to 0.08%
 
Androgenic Alpaca

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pegasus2 said:
5mg is a little low, but it should work. At that dose there is pretty much no risk of major side effects. Good luck.
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5mg per pump is the highest concentration I could find over the counter. I'm using 6 pumps per day, or 30mg. But at 6 pumps/day I'm going to be burning through the bottles I've bought on Amazon so it might get expensive. Ideally I'd like to find a doctor who would write me a prescription for a compounded estriol cream at a higher concentration.

I also found one of those grey market medication websites that sells 2mg oral estriol tablets. Would that be something worthwhile to add? I understand that part of the need for high doses of topical estriol is its poor absortion, so would a lower dose of oral be effective? I'd imagine oral estriol would have a higher risk of gyno
 
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JaneyElizabeth

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The @bridgeburn thread, to me, is far more useful but this thread is good for people who are extremely risk-averse. I don't think that anyone who hasn't been on a program like bridgeburn gets it. My question is: is anyone growing long flowing locks on this thread? If not then eh.... I am not interested in the regrowth of vellus hair that never goes anywhere or the way that you guys seem to have these endless cycles of shed followed by more tinkerering that still doesn't work. You either do this or you don't. You either want you hair to the point where you are consumed with it, or you don't.

I think that it is great that you guys are not so into your hair as I am. You have maturity and a sense of perspective but I want long flowing locks and this thread has little to no information related to that. Of course, I have already done the beautiful wife and children thing.

I am hoping that we can get more adventurous folks to come over to the @bridgeburn thread. I have been accumulating copious photo evidence of all aspects of estrogen-induced scalp hair regrowth and I have been at this going back to 1984, so there is little that I haven't tried except for unapproved treatments. Of course, they never go anywhere and they never will. Why? Because you need estrogen and lots and lots to regenerate hair from slick bald scalp.
 
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JaneyElizabeth

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Thank you, John. I obviously notice your extremely memorable avatar and have read many of your posts. I will go through this link that you provided:)
 
John Difool

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When you let yourself go the Estrogen Progesterone and strong AA blockers route at castration level and female range, you are playing a totally different game than most folks on this forum who complain getting gyno on Finasteride. So no wonder you like @bridgeburn post since he decided to use hrt just to keep his hair. In that situation you almost have no excuses no to regrowth some hair minus a few exceptions. But for most folks here it's like keeping their male attributes while regrowing their hair using one magical topical lotion which scammers are happy to offer or some futuristic treatment they will never be able to access. No wonder most of the conversations are boring to your liking.
 
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John Difool said:
When you let yourself go the Estrogen Progesterone and strong AA blockers route at castration level and female range, you are playing a totally different game than most folks on this forum who complain getting gyno on Finasteride. So no wonder you like @bridgeburn post since he decided to use hrt just to keep his hair. In that situation you almost have no excuses no to regrowth some hair minus a few exceptions. But for most folks here it's like keeping their male attributes while regrowing their hair using one magical topical lotion which scammers are happy to offer or some futuristic treatment they will never be able to access. No wonder most of the conversations are boring to your liking.
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I didn't say that it was boring but I might try to distinguish the two types of extreme protocols folks, i.e., those whose primary goal is avoiding gyno at all costs versus those who just titrate upwards as long as they keep seeing hair improvement. You are right that younger MtFs tend not to struggle with this since "male" hair is easily transformed into XX hair for those who never bald, but for older MtFs, there is nothing assured about regrowth at all from what I can discern and there have been several people who have tried fairly extreme MtF HRT protocols with lackluster results. I have always had more or less full coverage but I had diffuse thinning even on the sides. Right now, my interest has to do with the need for maintaining hormonal levels at adult female levels for six to 12 months before hair improvement might be noticeable. Because of my own situation leading to a hopeful crescendo, I hope to sort of provide real-time pictures and feedback because I never before even bothered with targets because all of my other HRT results were so uncanny but my hair was lagging somewhat. I also had a shed to full baldness last year and I have photographic evidence to show that such HRT sheds might be benevolent unlike other sheds that seem intertwined with male pattern baldness/Telogen Effluvium. Goddess bless.
 
John Difool

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Hormonal changed will do crazy things with your hair. Sticking to a plan is so far the best strategy to bring results. Too often you see folks switching their regimen more often than their undies.
 
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sorry if this is a stupid question: so can taking soy isoflavones help with hairloss such as genistein and daidzein?
 
Androgenic Alpaca

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John Difool said:
Try this:

https://www.empowerpharmacy.com/drugs/progesterone-cream
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Thanks for the link, that company looks like it produces a number of compounded medications that I think would be useful, although I feel like I'll have difficulty getting a doctor to prescribe some of the more nontraditional compounded medication.

Is the main benefit of topical progesterone its antagonism of the mineralcorticosteroid receptor? I understand that progesterone functions as an antigonadotropin, but surely topically applied progesterone won't have that strong of an effect on testosterone levels, right? I also know that topical progesterone is experimentally linked to improved skin health, but I'm not sure what mechanism causes that?

Also, is there any potential of progesterone being carcinogenic?
 
John Difool

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Androgenic Alpaca said:
For those with the proper gut bacteria to convert daidzein to (s)-equol, would a diet rich in isoflavones (either from a supplement or lots of soy) have a noticeable effect?
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It won't hurt if you have nutritional deficiencies or decided to quit pepsi or coke and drink soy milk instead but don't expect to beat your genes by just drinking soy milk or eating beans.
 
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