Gadgetine

It Begins. I purchased all the items for the SwissTemple Prostaglandin Protocol. Wish

Folliman

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I've read these studies before and I understand what is trying to be done here. The problem is that there is no evidence that what we are seeing is neogenesis and it is more likely to be existing miniaturized hair that is growing back due to growth factors from dermarolling causing DP cell proliferation.

No, Cotsarelis confirmed this is new hair. This is a mouse study, I'll give you that, but he cites dermatologists that documented the phenomenon in other animals and humans. So there IS evidence (and pretty strong), which is why Follica is under clinical trials right now. Maybe what you're really looking for is proof that this can be replicated in the human scalp. There is no proof yet (unless you count internet anecdotes); if you want proof you'll have to wait for Follica phase 3 trial results to be public.
 

mr_robot

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No, Cotsarelis confirmed this is new hair. This is a mouse study, I'll give you that, but he cites dermatologists that documented the phenomenon in other animals and humans. So there IS evidence (and pretty strong), which is why Follica is under clinical trials right now. Maybe what you're really looking for is proof that this can be replicated in the human scalp. There is no proof yet (unless you count internet anecdotes); if you want proof you'll have to wait for Follica phase 3 trial results to be public.

Follica is n't derma rolling, they're dermabrasing 2mm of skin off. We also don't know the compound they are using, but we do know they mention minoxidil in the patents. This dermarolling/Seti/PGE2 has nothing to do with them and is a hyposethsis based on studies, you can't say Follica will be proof this works, they're two different things.

The results shown don't look like neogenesis at all, what it looks like is thickened miniturised hair you'd get with a growth stimulator like minoxidil and it's very unlikely that you will get much further than this, in fact looks like how far ST got before he stopped updating.
 

Folliman

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Follica is n't derma rolling, they're dermabrasing 2mm of skin off. We also don't know the compound they are using, but we do know they mention minoxidil in the patents. This dermarolling/Seti/PGE2 has nothing to do with them and is a hyposethsis based on studies, you can't say Follica will be proof this works, they're two different things.

The results shown don't look like neogenesis at all, what it looks like is thickened miniturised hair you'd get with a growth stimulator like minoxidil and it's very unlikely that you will get much further than this, in fact looks like how far ST got before he stopped updating.

I know Follica isn't dermarolling. Probably what they're doing is the most optimal wounding method for hair growth, but dermaneedling is what users have right now and that's what they're trying (because there's evidence backing it up). And yes, no one knows what the compound is but it's obvious that WNTs are involved, their importance has been established already and they're mentioned in the patent as well. By the way, Minoxidil activates the b-catenin pathway, that must be why they're studying it, it goes hand in hand with WNT.

You fail to mention that Lithium Chloride, a WNT agonist, is part of the ST protocol. This part of the protocol is precisely based on what Follica is doing. Again, it's probably not the most optimal, but it's the closest thing we have right now.

I don't think Follica or PGs are full solutions in isolation. We will have to combine them to see full results, and that is exactly what is being attempted here.
 

Dench57

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Choose your God.

http://www.hairestorationetwork.com/eve/image.php?u=182998&dateline=1363475737
tsuji.jpg



Swiss temples in 2016 = COPE

ByKHlH6.jpg
 

buckthorn

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Gone

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If hair has more difficulty growing through scar tissue, then wounding might not be a viable long term solution. I commend the OP for taking the time to show such consistent reports though. I don't see results either, however there could be an element contributing to pilosebacious integrity which just doesn't manifest as hair growth, and I can't just write it off as totally ineffective.
 

inmyhead

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If hair has more difficulty growing through scar tissue, then wounding might not be a viable long term solution. I commend the OP for taking the time to show such consistent reports though. I don't see results either, however there could be an element contributing to pilosebacious integrity which just doesn't manifest as hair growth, and I can't just write it off as totally ineffective.
there is no scars from such small wounds lol
 

Gone

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I see what appears to be a change in skin color. Even a tiny wound of a great enough depth can cause scar tissue.
 

inmyhead

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I see what appears to be a change in skin color. Even a tiny wound of a great enough depth can cause scar tissue.

give me science or what you saying doesn mean anything. Because everywhere i read i see that small wounds DO NOT cause scars.
 

Gone

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I didn't say hair couldn't grow in scar tissue, but fibrosis is a factor in late male pattern baldness.
 

yayapapaya

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I've read these studies before and I understand what is trying to be done here. The problem is that there is no evidence that what we are seeing is neogenesis and it is more likely to be existing miniaturized hair that is growing back due to growth factors from dermarolling causing DP cell proliferation.

Those hairs start growing after 2-3 weeks of applying seti without any dermarolling. Not a lot, but it is new hairs.
 
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