Italian Hair Loss Lotion To Hit The Market In 2016

[Aliens]

Issue is that if you are suffering from alopecia so much that you rely on finasteride (like myself and other people) chances are that you are probably also suffering from self-esteem, confidence issues... Let it be clear I am not saying that only people anxious/despressed... suffers from alopecia when it kicks in, but that baldness has for a lot of us a very big impact on the way we see ourselves and interact with other people. So much that we accept the (potential) side effects of things like finasteride.
So when it is reported that people taking finasteride becomes despressed I consider there is a huge bias over this finding. Is finasteride the cause of despression/anxiety or does it rather reflect the an effect of the cause (alopecia) pushing people to take finasteride?
I do not know, but at the end my point here is that blaming finasteride for mental issues assess a unique and causal link between finasteride and despression, and, worse, it again overlooks and diminishes in public perception the fact that alopecia can be something really affecting quality of life. And for me as long and alopecia will not be taken as a real issues we will not see any efficient and available to most people treatment.
Yes alopecia is probably hard to cure, but I do not think everything that could be done to treat it is done because apart from sufferers tons of people do not take the issue seriously. And I am not even talking about jokes on sufferers or the way people look down at them for confidence issues.
Very sad situation.

 

[dermrafok]

dutasteride affects the 5ar that is found in the brain but finasteride does not

Neuroactive steroid levels and psychiatric and andrological features in post-finasteride patients. (2017).
https://www.ncbi.nlm.nih.gov/pubmed/28408350

A Review of the FAERS Data on 5-Alpha Reductase Inhibitors: Implications for Post-Finasteride Syndrome (2018).
https://www.ncbi.nlm.nih.gov/pubmed/29960004

"Finasteride use was reported with many sexual AEs including diminished libido, erectile dysfunction and ejaculatory complaints. Other common AEs included dermatologic, metabolic and psychological/neurological complaints. There were more AE reports with the 1mg dose than the 5mg dose". "FAERS data suggests that finasteride exposure is reported with a diverse collection of symptoms".

You have to accept that Finasteride is a disaster.

 

[BalderBaldyBald]

View attachment 92078

Even their logo is garbage.

Brotzu should have partner with Ferrero to make profit of Nutella's riots

 

[IHadSexWithAHairPiece]

Finasteride gave me mammary tissue around nipple hasn’t hardened yet but my tits are now ruined. Can brotzu be applied topically to reverse it? Anyone?

 

[BalderBaldyBald]

Finasteride gave me mammary tissue around nipple hasn’t hardened yet but my tits are now ruined. Can brotzu be applied topically to reverse it? Anyone?

Try female semen, it works !

 

[MomoGee]

 

[MomoGee]

 

[Guts]

 

[washed_up]

Neuroactive steroid levels and psychiatric and andrological features in post-finasteride patients. (2017).
https://www.ncbi.nlm.nih.gov/pubmed/28408350

A Review of the FAERS Data on 5-Alpha Reductase Inhibitors: Implications for Post-Finasteride Syndrome (2018).
https://www.ncbi.nlm.nih.gov/pubmed/29960004

"Finasteride use was reported with many sexual AEs including diminished libido, erectile dysfunction and ejaculatory complaints. Other common AEs included dermatologic, metabolic and psychological/neurological complaints. There were more AE reports with the 1mg dose than the 5mg dose". "FAERS data suggests that finasteride exposure is reported with a diverse collection of symptoms".

You have to accept that Finasteride is a disaster.

I'm not really sure I understand the point in all of this. Sure it's a disaster, for the unfortunate few who were not built to take it. v**** is a disaster for the unfortunate few who experienced debilitating priapism or permanent blindness from it. Aspirin is a disaster to the unfortunate few parents who gave it to their children just to reduce their fever and then had them die as a result. So if you can find some studies that show dramatically higher incidences of side effects than the countless studies that have shown so far then let's see those. Better yet, take that data to the FDA so that it's brought to their attention. No one is cramming any pills down your throat and the small possibility of side effects are clear to anyone before they take it.

Your own link even alludes to some of this being mental rather than physiological.

"Possibly related to labeling changes, from 2011 to 2014, there was a significant increase in adverse events (AEs) reported involving 1mg dosing."

So what is your point other than whining?

 

[AnArcticTaco]

So if you can find some studies that show dramatically higher incidences of side effects than the countless studies that have shown so far then let's see those.

Ask and ye shall receive

Adverse Event Reporting in Clinical Trials of Finasteride for Androgenic Alopecia: A Meta-analysis.

Link: https://www.ncbi.nlm.nih.gov/pubmed/25830296

"Of 34 clinical trials, none had adequate safety reporting, 19 were partially adequate, 12 were inadequate, and 3 reported no adverse events. Funnel plots were asymmetric with a bias toward lower odds ratio for sexual adverse effects, suggesting systematic underdetection. No reports assessed adequacy of blinding, 18 (53%) disclosed conflicts of interest, and 19 (56%) received funding from the manufacturer."

Here's another one, however, you can't access it unless you purchase it or your university provides you access: https://jamanetwork.com/journals/jamadermatology/article-abstract/2212243

I recommend giving it a read if you can but the first page preview makes a very important remark:

The same methodology of reporting sexual side effects for SSRI was used to report sides for finasteride. For decades the medical community had a consensus that SSRIs had a sexual side effect rate of 1-3%, we have studies now saying anything from 30%-60%. Sound familiar?

 

[LeeBuckler]

I have one question to all of you. This is why I registered in this Forum:
If finasteride is that successfull like you are telling, why are guys like Justin Bieber balding???? He made jokes about Prince William that he becomes bald but "nobody has to be bald cause you can take finasteride" Justin Bieber said. So Bieber took/takes finasteride and he is still balding and it becomes worse every day ...
Why is Ed Sheeran balding if finasteride is so good?
Why is Mario Götze balding if finasteride is so good?

DO you think that this celebritys are the 2% who have to deal with the side effects ?!? I can't imagine

This is the reason why I am not taking finasteride (

 

[washed_up]

Ask and ye shall receive

Adverse Event Reporting in Clinical Trials of Finasteride for Androgenic Alopecia: A Meta-analysis.

Link: https://www.ncbi.nlm.nih.gov/pubmed/25830296

"Of 34 clinical trials, none had adequate safety reporting, 19 were partially adequate, 12 were inadequate, and 3 reported no adverse events. Funnel plots were asymmetric with a bias toward lower odds ratio for sexual adverse effects, suggesting systematic underdetection. No reports assessed adequacy of blinding, 18 (53%) disclosed conflicts of interest, and 19 (56%) received funding from the manufacturer."

Here's another one, however, you can't access it unless you purchase it or your university provides you access: https://jamanetwork.com/journals/jamadermatology/article-abstract/2212243

I recommend giving it a read if you can but the first page preview makes a very important remark:

The same methodology of reporting sexual side effects for SSRI was used to report sides for finasteride. For decades the medical community had a consensus that SSRIs had a sexual side effect rate of 1-3%, we have studies now saying anything from 30%-60%. Sound familiar?

It's truly amazing how you morons have nothing but confirmation bias and fearmongering on your side but link a bunch of weakly sourced "studies" and act as though you're on the side of reason and science.

I just can't believe you seriously posted a "study" that merely says "some of these safety trials MAY not have been up to our arbitrary standard and MAY have had some systemic biases but we have nothing of our own to show their conclusions were misrepresentations."

Think about what this is even stating. 56% received funding from the manufacturer. Sure sounds scary and terrible but where has it ever been stated that you cannot conduct a credible safety trial while receiving funding from a manufacturer. I knew biology students who worked on such trials and their funding came from manufacturers of the product being tested but I never doubted their work. In fact, sometimes it was even MORE rigorous because they were deadly afraid of future potential lawsuits if they got it wrong.

The fact remains that after all these years of hysteria, no one has been able to get a couple hundred random guys into a credibly conducted study and show anything which is out of line with the safety profile for these drugs that we've been led to believe. That's just the cold hard facts as it stands today, maybe it will change in the future but the evidence has yet to be found.

 

[irishlad8787]

I have one question to all of you. This is why I registered in this Forum:
If finasteride is that successfull like you are telling, why are guys like Justin Bieber balding???? He made jokes about Prince William that he becomes bald but "nobody has to be bald cause you can take finasteride" Justin Bieber said. So Bieber took/takes finasteride and he is still balding and it becomes worse every day ...
Why is Ed Sheeran balding if finasteride is so good?
Why is Mario Götze balding if finasteride is so good?

DO you think that this celebritys are the 2% who have to deal with the side effects ?!? I can't imagine

This is the reason why I am not taking finasteride (

i took finasteride for 3 years and continued to bald, it is not some wonder drug by any stretch. It slows down hairloss in most cases that about it.

 

[washed_up]

I have one question to all of you. This is why I registered in this Forum:
If finasteride is that successfull like you are telling, why are guys like Justin Bieber balding???? He made jokes about Prince William that he becomes bald but "nobody has to be bald cause you can take finasteride" Justin Bieber said. So Bieber took/takes finasteride and he is still balding and it becomes worse every day ...
Why is Ed Sheeran balding if finasteride is so good?
Why is Mario Götze balding if finasteride is so good?

DO you think that this celebritys are the 2% who have to deal with the side effects ?!? I can't imagine

This is the reason why I am not taking finasteride (

Ashton Kutcher took dutasteride for 10 years and completely halted his hair loss. He says he stopped when he was trying to have a baby and it started up again. I don't even know if Sheeran or Gotze take anything for their hair.

 

[IHadSexWithAHairPiece]

You fools. You won’t be talking sh*t when I go from nw7 to nw0 with my trusted brotzu. All you non-believers will be sorry.

 

[IHadSexWithAHairPiece]

Ashton Kutcher took dutasteride for 10 years and completely halted his hair loss. He says he stopped when he was trying to have a baby and it started up again. I don't even know if Sheeran or Gotze take anything for their hair.

That’s why he was looking like a tranny in most of his movies.

 

[washed_up]

That’s why he was looking like a tranny in most of his movies.

I don't know you, but I'm willing to wager he's in better shape than you are. No gyno, no fat, and apparently he wasn't castrated or made infertile by dutasteride because he's having kids.

 

[IHadSexWithAHairPiece]

I don't know you, but I'm willing to wager he's in better shape than you are. No gyno, no fat, and apparently he wasn't castrated or made infertile by dutasteride because he's having kids.

If you see bridgeburn’s latest pics and Ashton’s old movies you will see the same high cheekbones and oval face. Ashton was always striking me as weird. Rounded shoulders, relatively thin almost as weak. His facial expressions were always feminine go watch his scenes when he cries on the butterfly effect. Or watch his “sex” face on scenes with Anne Heck. I’m not saying he’s ugly and I’m fact he’s a good actor. But facts are facts. I never knew what was it that I found weird in him. Now after years I learn about antiandrogens and his ten year use of Duta. Things are now clear.

 

[PuffyPink]

I was always saying, that fidia acts professional, they never made up false hopes or gave wrong deadlines.

1.5 years ago, they didn’t said things like: release soon, or the best product in the world, they just said by 2018.

And if you think logical about it, they still act professional. 2018 is just half gone, so out of this view, there is no reason to give an update.
But if you are a balding c*** like Iam, you can’t think logical. Why is it so hard, to give an update after this shitty presentation, why is it so hard to answer questions (on phone, via mail, or if a mod of a big forum is asking)

This whole thing is a mess. The biggest mistake was, that we didn’t made a big groupbuy in 2016. because no matter whether it is working or not, this would have saved us a lot of trouble.

I still hope this is working, and Iam still like 50:50, but if not this thread should be a lesson for everyone. But to be honest no one is going to learn anything. We had the same promising treatments already a thousand times in history and still we are always putting an irrational amount of hope in each new treatment.

Best example are people who are saying that it is not important whether brotzu is working, because replicel will be out soon, or choi and Tsuji will be a definit cure. There is absolutely no evidence, that one of those products is going to work well on humans nor that they will release it. Or st least the evidence is not bigger then it was for brotzu.

So please everyone in the name of our mental health, don’t jump on every new hype and forget about the last time we had a situation like in this thread.

 

[LeeBuckler]

I was always saying, that fidia acts professional, they never made up false hopes or gave wrong deadlines.

1.5 years ago, they didn’t said things like: release soon, or the best product in the world, they just said by 2018.

And if you think logical about it, they still act professional. 2018 is just half gone, so out of this view, there is no reason to give an update.
But if you are a balding c*** like Iam, you can’t think logical. Why is it so hard, to give an update after this shitty presentation, why is it so hard to answer questions (on phone, via mail, or if a mod of a big forum is asking)

This whole thing is a mess. The biggest mistake was, that we didn’t made a big groupbuy in 2016. because no matter whether it is working or not, this would have saved us a lot of trouble.

I still hope this is working, and Iam still like 50:50, but if not this thread should be a lesson for everyone. But to be honest no one is going to learn anything. We had the same promising treatments already a thousand times in history and still we are always putting an irrational amount of hope in each new treatment.

Best example are people who are saying that it is not important whether brotzu is working, because replicel will be out soon, or choi and Tsuji will be a definit cure. There is absolutely no evidence, that one of those products is going to work well on humans nor that they will release it. Or st least the evidence is not bigger then it was for brotzu.

So please everyone in the name of our mental health, don’t jump on every new hype and forget about the last time we had a situation like in this thread.

Why there is "no evidence that one of those products is going to work well on humans" for Replicel? RCH-01 Phase I was tested on Humans and stops at least the hairloss in every participant. I can't understand why People like you are ignoring the good results of RCH-01. You act like Replicel was only tested on mice...