Italian Hair Loss Lotion To Hit The Market In 2016

NormanNorwood

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I could have sworn only like 30% of "western" people can convert or process S-Equol into lowering DHT whereas 60% of Asians (which explains lower hairloss) can.

Surely you'd have to be part of the "30%" (providing you aren't Asian) who benefits from oral S-Equol?

Even then we don't know what is necessarily considered a good dose for an oral supplement. It's all guess work I suppose but I would be tempted to try if all else fails.
 

Afro_Vacancy

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30% of westerners convert soy isoflavones to s-equol, but that's an upper bound since most westerners eat very little soy regardless.
 

NormanNorwood

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30% of westerners convert soy isoflavones to s-equol, but that's an upper bound since most westerners eat very little soy regardless.

So let's say you're lucky to be part of the 30% and then you start eating a lot of Soy or Soy isoflavones your body may start to produce S-equol?

If you aren't one of the 30% s-equal supplements could work I guess. Asian people don't have higher rates of erectile dysfunction or other finasteride like sides from more DHT surpression.
 

Afro_Vacancy

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So let's say you're lucky to be part of the 30% and then you start eating a lot of Soy or Soy isoflavones your body may start to produce S-equol?

If you aren't one of the 30% s-equal supplements could work I guess. Asian people don't have higher rates of erectile dysfunction or other finasteride like sides from more DHT surpression.

I do wonder if that's actually measured.

"Asian people are healthy" is also one of the arguments used to defend monosodium glutamate. If MSG was as bad for you as some fearmongers say, half of Asia would drop dead.

And to answer your questions: yes.
 

WangMQ

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30% of westerners convert soy isoflavones to s-equol, but that's an upper bound since most westerners eat very little soy regardless.
Asians don't actually eat as much soy as the rest of the world think (at least not nowadays haha). But it's true that Japanese eat a considerable amount of soy food daily and they have lower rates of prostate problems. Still, it's worth investigating how significant that daily intake can affect people's health and endocrine system. (which is also why I'd like to stay calm about the possible sides of this one too!)
 

gagost02

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If you'd like to supplement your diet with equol:

https://www.amazon.com/EQUELLE-x300...e=UTF8&qid=1467863851&sr=8-2&keywords=s-equol
112 tablets each with 2.5 mg of s-equol, for $150.
Might be a 3-pack, in which case you're effectively paying $50 each, not sure it's a bad add.

Buy directly from the company:
https://www.otsuka.co.jp/en/product/equelle/
Though I can't find the "buy" button nor a price.


http://www.otsuka.co.jp/eql/equol/index.html
http://www.otsuka.co.jp/eql/shop/index.html
http://www.otsuka-plus1.com/shop/pa..._campaign=equelle_about_equelle&wapr=577e789b
 

I.D WALKER

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Semantic Scholar Home
The Role of Colonic Bacteria in the Metabolism of the Natural Isoflavone Daidzin to Equol
Food Chem
  • 2015

Absorption, distribution, metabolism, and excretion of isoflavonoids after soy intake

Counts of Slackia sp. strain NATTS in intestinal flora are correlated to serum concentrations of equol both in prostate cancer cases and controls in Japanese men. Asian Pac
  • Y Sugiyama, Y Nagata, F Fukuta, A Takayanagi, N Masumori, T Tsukamoto +8 others
  • J. Cancer Prev
  • 2014
https://www.semanticscholar.org/pap...sell/2d06999d954b18d48319bad2efa4ae18cb1874bd
 

abcdefg

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In my mind this whole lotion is based around whether s-equol can stop DHT or not. If you ignore androgens and it does not stop them the rest of the stuff might give some mild regrowth but you will continue to lose hair anyway.
We just need some hormone panels of a few people before they took s-equol, and a month later DHT. Did it go down and how much? can dose/response curve be figured. It all hinges on s-equol IMO which I still am skeptical will work nearly as well as finasteride, but you never know.
Eating soy and praying for that 30 percent is not worth it IMO. Who knows how much you even need to consume because again we have no idea if s-equol works and what dose corresponds to what reduction in DHT. Without that its pointless. You might have to consume it in quantities that would kill you who knows.
 

Afro_Vacancy

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In my mind this whole lotion is based around whether s-equol can stop DHT or not. If you ignore androgens and it does not stop them the rest of the stuff might give some mild regrowth but you will continue to lose hair anyway.
We just need some hormone panels of a few people before they took s-equol, and a month later DHT. Did it go down and how much? can dose/response curve be figured. It all hinges on s-equol IMO which I still am skeptical will work nearly as well as finasteride, but you never know.
Eating soy and praying for that 30 percent is not worth it IMO. Who knows how much you even need to consume because again we have no idea if s-equol works and what dose corresponds to what reduction in DHT. Without that its pointless.

Brotzu said that equol accounts for ~45% of the effectiveness.

Also I'm pretty sure that equol doesn't reduce DHT levels, it just makes it inert.
 

bags

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Brotzu said that equol accounts for ~45% of the effectiveness.

Also I'm pretty sure that equol doesn't reduce DHT levels, it just makes it inert.

That would be a dreeeeaaammm. Thats what Im hoping this lotion does as well. Allows us to stay normal hormonally in every way possible, as long as we apply the lotion, the application areas will be DHT resistant.

A topical DHT blocker that promotes regrowth with ZERO SIDES!

FFS! I guarantee you all the money in the world if something like this came out all the shelved patents that the greedy corporate devils have shelved will get developed, and we will have an array of solutions like this out within 5 years easy with heavy marketing behind them so the current snakes can keep their market share.
 

NormanNorwood

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In my mind this whole lotion is based around whether s-equol can stop DHT or not. If you ignore androgens and it does not stop them the rest of the stuff might give some mild regrowth but you will continue to lose hair anyway.
We just need some hormone panels of a few people before they took s-equol, and a month later DHT. Did it go down and how much? can dose/response curve be figured. It all hinges on s-equol IMO which I still am skeptical will work nearly as well as finasteride, but you never know.
Eating soy and praying for that 30 percent is not worth it IMO. Who knows how much you even need to consume because again we have no idea if s-equol works and what dose corresponds to what reduction in DHT. Without that its pointless. You might have to consume it in quantities that would kill you who knows.

It's a shame oral S-Equol is so expensive or people could have bought this and already tested it.

There is another thread somewhere here of people discussing making Brotzu's lotion by buying the ingredient.

Someone posted a link to a lab that sells it. It was £21 for 1gram :(

I did find supplements where each pill was 750mg of Soy Isoflavones, if you can convert it into S-Equol it might help but I'm not sure you could ever turn 750mg of that into anything meaningful quantities of S-Equol for hairloss.
 

Swoop

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I'm pretty surprised at the low DGLA content in this lotion. Did anyone have the same thoughts?

http://www.ncbi.nlm.nih.gov/pubmed/22411689

Dihomo-γ-linolenic acid (DGLA) is one of the polyunsaturated fatty acids, and is expected to show anti-allergic activity. We examined the effects of supplementation with DGLA-enriched oil (450 mg as free DGLA) for 4 weeks in healthy adults in a randomized controlled study.
 

JLC

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This thread alone has had over 200000 views, I'm really suprised this lotion hasn't been covered in the general press outside of dedicated hairloss blogs.
 

abcdefg

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This thread alone has had over 200000 views, I'm really suprised this lotion hasn't been covered in the general press outside of dedicated hairloss blogs.

Who cares about the mainstream press. Bringing attention to male pattern baldness means nothing really. The press said in 2012 male pattern baldness would be cured in 2 years from PGD 2 discovery. I am still waiting to see that so all that media coverage really accomplished a great deal there. They have zero credibility and just exist to entertain not inform.
If it works the people that matter will find out and use it. Outside of the isolated hair loss community their opinions dont mean much if anything.
 

Xaser94

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Fidia emailed me and said news will be posted after summer holiday. I honestly beileve this could be something for people that have been losing hair for less than 10 years

Can anyone else confirm if they got a similar response from Fidia? Or if they could just paste the whole email, that would be cool. Thanks.
 

Blackber

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I know they changed the ingredients to avoid clinical trials but I was curious if they need to apply for "cosmetic" approval before they market the lotion in the US.

From the FDA's website:

"FDA does not have the legal authority to approve cosmetics before they go on the market, although we do approve color additives used in them (except coal tar hair dyes).

However, under the law, cosmetics must not be "adulterated" or "misbranded." For example, they must be safe for consumers when used according to directions on the label, or in the customary or expected way, and they must be properly labeled. Companies and individuals who market cosmetics have a legal responsibility for the safety and labeling of their products.

FDA can take action against a cosmetic on the market if we have reliable information showing that it is adulterated or misbranded. FDA takes action within our legal authority, based on public health priorities and available
"

Seems that as long as they meet the above requirements they would be able to sell it in the US without too many hurdles.

Hopefully it works and they bring it to market.
 

Tomtom21

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@Youngerman any word back from fidia since the holiday is over now? What email did you use to email fidia? Ill shoot theman email too... Also does it have to be in english or italian the email?
- tomtom
 
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