Kintor has started Phase 3 trial in China for Pyrilutamide

kuba197

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Should be stronger RU. However, some of the fellas in the discord group were on RU and having side effects. Not having any side effects on Pyri.
And that's good information. I hope i can switch to Pyril from RU and the end of the year because I'm getting gyno. Good luck!
 

whatevr

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Due to the fact that supposedly its The same mecanismo as ru, fluridil, etc, no?

Yes, but it's a brand new molecule, and drug design isn't foolproof, in the sense that drugs sometimes do undesirable things they weren't meant to do... Case in point, enzalutamide might give you seizures through its GABA antagonism, so you'd have awful side effects, and that doesn't guarantee it would do anything for your hair, etc.
 

kuba197

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Yes, but it's a brand new molecule, and drug design isn't foolproof, in the sense that drugs sometimes do undesirable things they weren't meant to do... Case in point, enzalutamide might give you seizures through its GABA antagonism, so you'd have awful side effects, and that doesn't guarantee it would do anything for your hair, etc.
Are you testing pyril bro? Or you gave up on everything?
 

Znx

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Yes, but it's a brand new molecule, and drug design isn't foolproof, in the sense that drugs sometimes do undesirable things they weren't meant to do... Case in point, enzalutamide might give you seizures through its GABA antagonism, so you'd have awful side effects, and that doesn't guarantee it would do anything for your hair, etc.
Aw i see... thank you for explaining!
 

fashy

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I feel like kintors overall plan was to have combination therapy using the degrader + pyril for any major efficacy to be seen.

the topical cream would at best slow down hairloss (like every other anti androgen therapy)

Not true. Pyrilutamide will be better than RU.
 
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