Kintor has started Phase 3 trial in China for Pyrilutamide

Dr sanches

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Every study criteria says this, no one checks.
Pretty easy to check if they saw your dht was in the gutter via blood tests they would know you are on finasteride and finasteride stays in the blood for months
 

Nebula74

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I still do not understand why breezula did so well initially and then so poorly when other anti androgens like finasteride or dutasteride really start to show the best results after 12-15 months. its strange because anti androgens take a long time to show their positive effects however with this one it seems to be potent initially and then diminish(breezula). personally I am hopeful that Pyrilutamide does not have this property
I think it might have something to do with the MOA too, as we know how hair becomes more sensitive to androgens over time, so maybe AR blockers require increased dosages over time to block the same amount of androgens, whereas 5aris significantly DHT production, and therefore do a better job at solving the issue at its root, if you discount for side effects
 

Dr sanches

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I think it might have something to do with the MOA too, as we know how hair becomes more sensitive to androgens over time, so maybe AR blockers require increased dosages over time to block the same amount of androgens, whereas 5aris significantly DHT production, and therefore do a better job at solving the issue at its root, if you discount for side effects
No this isn’t the reason the reason breezula doesn’t do well is it because it’s binding affinity is low . Ru literally had a 70 Times higher binding affinity both ru and breezula don’t compete for dht as well as pyri
 

Kagaho

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fashy

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Placebo at nearly 10 hairs? Sorry but this drug is worthless. Epic fail by kintor. These results look identical to breezula. And if the results were a 6 month trial then it will probably lose efficacy like breezula did after 12.

Just make sure you don't buy any when it gets released on the market. You won't need such worthless stuff anyways.
 

Intrigued77777777

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Placebo at nearly 10 hairs? Sorry but this drug is worthless. Epic fail by kintor. These results look identical to breezula. And if the results were a 6 month trial then it will probably lose efficacy like breezula did after 12.
I'm confused. What has the placebo (i.e. no drug) result got to do with the effectiveness of the....... drug?
 

Bread24

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When are the results expected to be released for kintor? At 5Mg QID with an mean change in haircount of 22... 20 mg probably woudl have better results.
What were the results with minoxidil? Anyone know?
 

Nebula74

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When are the results expected to be released for kintor? At 5Mg QID with an mean change in haircount of 22... 20 mg probably woudl have better results.
What were the results with minoxidil? Anyone know?
20mg goes systemic
 

Diffused_confidence

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Yeah Minoxidil studies had placebo results hella high people should wait till results get fully released
Minoxidil is barely helpful at stopping hair loss. If this just is just as effective as minoxidil then why not use minoxidil? When you look at the finasteride and dutasteride studies, hair counts went DOWN for the placebo.

It's a tough pill to swallow but kintor is not the answer. Complete failure, as usual
 

Diffused_confidence

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We can never win.
 

Anatman

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My goodness. It should be clear that we all represent a healthy skepticism here, but with your statements you are even competing with the biblical apocalyptic prophets.
1. we all know that KX will not be a cure. for me personally it will absolutely do if it will be anywhere near as good as finasteride with fewer side effects.
2. is not 100% sure if these results are real. until nothing has been officially confirmed, I'll reserve my opinion. That's too speculative.
3. We don't know if and why the numbers are so high, if they are correct. This can be for a number of reasons. perhaps this will be considered and observed in the ongoing third trial.

I will not blindly hope, nor will I blindly summon the Baldocalypse. I will wait for the results of Trial II+III. It remains exciting. And should everything fail: 2 Kings 2:23ff. Baldies need bears.
 
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