New Studies Show Vit D Implicated In Hair Loss And Calcipotriol
- Thread starter Jk1
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It all makes sense now, DHT makes men horny and have sex more and catch all kinds STD's, which in turn inhibits VDR, then because of that they start balding and become unattractive and have to pay prostitutes to be able to get sex which then exposes them to even more bacteria and disease and accelerates the balding process
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It is known that inherited sensitive follicles are being affected by androgens, just like every other tissue that can be morphed with hormones. The genetic code to create these follicles just happened to supply them with insufficient resistance to androgens.
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My last comment was a joke, but now I'm serious, there surely must be a lot of truth in these Vitamin D theories. Hair could serve an evolutionary purpose to protect our scalps/skin from UV rays. Fish and water creatures don't have hair, it's something that Animals on land have! or feathers.
This all seems to make sense and be tied together. If Estrogen can activate VDR then women bald less because their scalps are "tricked" into thinking it needs to grow hair to protect from the sun. Some people claim that taking vitamin D supps increased hairloss and I believe that makes sense because of this:
Vitamin D3 that is taken in a supplement is not the active form of Vit D, It has to get converted later. Correct me if I'm wrong in interpreting these science words above, but this says to me that VitD3 converts cholesterol into pregnenolone and then that pregnenolone could get converted into progesterone or DHEA, progesterone is a precursor to many many hormones and although has some 5 alpha reductase inhibiting ability, can also get turned into Testosterone and other Androgens later on, DHEA can also get converted into many things according to above which may or may not help your hair. But exposure to sunlight causes the Pregnenolone to get turned into Vitamin D! which is what we want to upregulate the VDR.
Maybe thats why the supplementation doesn't work and could possibly make it worse. And even if Supplementing does increase serumn vitamin D, and upregulates VDR, whats specifically important for hair is to upregulate VDR in the Skin to initiate anagen phase of hair, not all over the body in places like bones.
I think moderate Sun or UVB exposure is best, obviously getting so much exposure that you get a Tan could be too much because darker skin will require more exposure to get the same amount of Vitamin D.
This all seems to make sense and be tied together. If Estrogen can activate VDR then women bald less because their scalps are "tricked" into thinking it needs to grow hair to protect from the sun. Some people claim that taking vitamin D supps increased hairloss and I believe that makes sense because of this:
Vitamin D3 that is taken in a supplement is not the active form of Vit D, It has to get converted later. Correct me if I'm wrong in interpreting these science words above, but this says to me that VitD3 converts cholesterol into pregnenolone and then that pregnenolone could get converted into progesterone or DHEA, progesterone is a precursor to many many hormones and although has some 5 alpha reductase inhibiting ability, can also get turned into Testosterone and other Androgens later on, DHEA can also get converted into many things according to above which may or may not help your hair. But exposure to sunlight causes the Pregnenolone to get turned into Vitamin D! which is what we want to upregulate the VDR.
Maybe thats why the supplementation doesn't work and could possibly make it worse. And even if Supplementing does increase serumn vitamin D, and upregulates VDR, whats specifically important for hair is to upregulate VDR in the Skin to initiate anagen phase of hair, not all over the body in places like bones.
I think moderate Sun or UVB exposure is best, obviously getting so much exposure that you get a Tan could be too much because darker skin will require more exposure to get the same amount of Vitamin D.
Agree with everything said here...do you think its the same with cod liver oil ? Or does its VIt A canvel this bad effect out ?
Note uvb therapy was used in the past for male pattern baldness ( some people got skin cancer from this i.e tanning beds are also banned in some countries ) and today we use LLT again similar to sun. So maybe their is no alternative than sun on the head and body ? Uv light in skin downregulates immmune response and helps many such issues like psoriassis and seb dermatitis.
On that note long hair and a beard are a bad idea if u want to increase vit d from head.
http://www.twcenter.net/forums/showthread.php?709179-Persian-and-Egyptian-Skulls
Effect covering head with a turban and long beard most likely... caused weak skulls due to lack of vit D ! So definetly does make a big difference so no wounder body tries to adapt with hairloss to get more vit d.
Effect covering head with a turban and long beard most likely... caused weak skulls due to lack of vit D ! So definetly does make a big difference so no wounder body tries to adapt with hairloss to get more vit d.
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I'm not sure how good vit A is for hair, I think it can be good and bad maybe depending on the dose and frequency, there's also mixed results with tretinoin. I'm also thinking how sun damages skin and could increase wrinkles long term, and Minoxidil decreases Collagan. I've heard that collagen is higher in bald scalp. 4X higher, So maybe that's part of why minoxidil and UVB is effective ?? too much collagen can be bad perhaps?
now that you mention it, most of my hair loss happened very quickly and suddenly, I don't remember exactly how long it took but it was sometime between the years 16-17, I loved my hair and for that reason I let it grow long, I actually had a curly brown white man's fro. that was probably a mistake for my Vit D. I never realized that I was balding until one terrible day I lifted my hair and realized my hairline was f*****g destroyed. It was a very all of a sudden shock. I was past a Norwood 2 maybe even Norwood 2.5, and my hairline recceded very slowly over the years, now I'm 26 and Norwood 3 i think. I've been NOrwood 3 for awhile but in the past few years, I got more thin all over the top. I never had hair that was that long again since my teens, and i definitely have not been a fan of the sun all these years cause im white and burn easy.
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..Maybe
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darker skin absorbs less vit D, so don't get too tan
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Actually you may not have been wrong about the concealer making your hair fall. It clearly did it to me too, while my hair loss was stabilized from finasteride and minoxidil. It was obvious because when I stopped, my hair loss stopped too. I found it weird like how can my hair fall while i'm on both finasteride and minoxidil? Those two always work for me. But to be honest, I was really overusing toppik. When I noticed toppik was accelerating my hair loss, I thought I was suffocating my hair follicles or something. I'm not exactly sure how it made them fall, but I thought it was just that I was covering my hair follicles with fibers too much and they were dying or something, because they couldn't "breathe". I stopped using concealer because of this.
Regarding Topic conceiler i wounder if again vit d on scalp is the reason as it blocks the sun on scalp ? I also wondered about why it is the same people who start getting thick beard also stary loseing hair ? I wounder if us with this vit d receptor defect are just on the border of hair growth and add another more factor like low sun expossure lifestile then one more straw the breaks the camels back is beard or face stubble further reducing vit d levels ? Even shaven i would not be suprised if thick beard stubble reduces vit d a lot .
On that note i wounder if the vit d receptor on scalp work in a way that they are activated more the more days in the sun you are vs say 1 or 2 days weekends lots of sun or a Tan. I.e you may have same serum vit D levels in both scenarios but maybe its the daily exposure thay boosts vdr expression on scalp skin ? So in other words most people who work 5 days a week indoors modern day lifestyle never get enough sun exposure? .. whereas the homeless guy outside rarely have hairloss. We need studies to find what sun exposure is needed to activate vdr receptor in scalp skin...
https://www.ncbi.nlm.nih.gov/pubmed/15958597
So us with hairloss and vit d receptor need sun exposure for hairloss but also to protect against prostate cancer ! Funny that link to finasterdine..prostate. hairloss vdr seem to be all related
So us with hairloss and vit d receptor need sun exposure for hairloss but also to protect against prostate cancer ! Funny that link to finasterdine..prostate. hairloss vdr seem to be all related
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But don't you find it rather odd that some men don't become "sensitive" until they're 36? Or 48? Or 59?
I wonder if the estrogen receptor (not estrogen level itself) is somehow better in some men (and women of course) And the androgen receptor is way too strong/expressed in us? But why does this change?
Gahhhh I don't f*****g know man
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Their resistance decreased below the point of their circulating androgens in certain amount of time. They may have already been gradually becoming more sensitive.
Sensitivity increases without the presense of androgens. Look at eunuchs when injected with testosterone, they reach whatever norwood level rapidly because androgen sensitivity increased even in the absense of androgens.