*coughs* prp, laser treatments, other bullshit cosmetic treatments *coughs*
Puretech Health - 2017 Annual Report (2018-04-16)
- Thread starter Noisette
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- follica puretech health
*coughs* prp, laser treatments, other bullshit cosmetic treatments *coughs*
I know most people here love this user but what he is saying here is just impossible. If they havent started phase III yet then it is impossible it will come out next year. That's just not how mrdicsl trials work.
The last trial is for a freakin' needling device and that's it.
In 2016, they said they planned to start the pivotal in 2017 with a market launch in 2018 most likely. They suffered about a six month setback on the timeline, so that should set them back about six months from their previous target; give or take.
But I'm sure you know the market and the process better than the people who've actually been through it as to make an accurate guess.
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Noisette
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Please, sorry for my long post, this one 
I don't want to mislead you, I just want to give you some informations If you want to give your thoughts on it, please share it
It's hard to say for sure if it will be minoxidil. But on their patent, they have tested differents compounds like Bimatoprost on their clinical trials .
We can say that they have several compounds for the first generation. @That Guy has explained very well the next generation compounds are testing in order to increase the number of neogenic hairs, terminal hairs.
Here, they have already "completed its clinical-stage development of a next-generation device and drug combination product "
So they have a drug combination product = the first generation of compounds.
It's nice to see that they are already on the next generation of compounds.
Here we can read an interview of Daphne Zohar :
" we are using existing compounds previously approved for systemic chronic use and reformulating them for topical acute use. We know these compounds are safe in people."
There's no questioning the market demand. A new therapy that could safely and effectively treat male and female pattern hair loss would swiftly seize a huge market. And Zohar says the same technology can potentially be applied to hair removal, skin pigmentation and more. But don't ask her to name the original compounds the company is reformulating for novel use - that's a trade secret for now."
So Follica have reformulated the existing compounds
Source: https://www.fiercebiotech.com/special-report/emerging-drug-developer-follica
What do you think about their previously timeline ? they expected to have a regulatory clearance (an FDA approval at the end of 2017 ?) . A short timeline.
We don't know the relationship between Follica and the FDA. Maybe they have a " Fast Track designation"
"
A drug that receives Fast Track designation is eligible for some or all of the following:
More details on what is a Fast Track : https://www.fda.gov/ForPatients/Approvals/Fast/ucm405399.htm
Maybe Kythera ? According to puretech, Doctor Cotsarelis is a founder of Kythera.
I don't want to mislead you, I just want to give you some informations
If you want to give your thoughts on it, please share it It's hard to say for sure if it will be minoxidil. But on their patent, they have tested differents compounds like Bimatoprost on their clinical trials .
We can say that they have several compounds for the first generation. @That Guy has explained very well
the next generation compounds are testing in order to increase the number of neogenic hairs, terminal hairs.Here, they have already "completed its clinical-stage development of a next-generation device and drug combination product "
So they have a drug combination product = the first generation of compounds.
It's nice to see that they are already on the next generation of compounds.
Here we can read an interview of Daphne Zohar :
" we are using existing compounds previously approved for systemic chronic use and reformulating them for topical acute use. We know these compounds are safe in people."
There's no questioning the market demand. A new therapy that could safely and effectively treat male and female pattern hair loss would swiftly seize a huge market. And Zohar says the same technology can potentially be applied to hair removal, skin pigmentation and more. But don't ask her to name the original compounds the company is reformulating for novel use - that's a trade secret for now."
So Follica have reformulated the existing compounds
Source: https://www.fiercebiotech.com/special-report/emerging-drug-developer-follica
What do you think about their previously timeline ? they expected to have a regulatory clearance (an FDA approval at the end of 2017 ?) . A short timeline.
We don't know the relationship between Follica and the FDA. Maybe they have a " Fast Track designation"
"
A drug that receives Fast Track designation is eligible for some or all of the following:
- More frequent meetings with FDA to discuss the drug's development plan and ensure collection of appropriate data needed to support drug approval
- More frequent written communication from FDA about such things as the design of the proposed clinical trials and use of biomarkers
- Eligibility for Accelerated Approval and Priority Review, if relevant criteria are met "
More details on what is a Fast Track : https://www.fda.gov/ForPatients/Approvals/Fast/ucm405399.htm
Hahaha
LMAO
Maybe Kythera ? According to puretech, Doctor Cotsarelis is a founder of Kythera.
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hate being cynical and negative, but all this looks like their intention is to drag their "research" out until someone comes up with an illuminating scientific breakthrough which they will then be ready to utilize and incorporate in their hypothetical treatment
tell me this doesnt look like it. as time passes, their narrative becomes less and less concrete product-oriented
tell me this doesnt look like it. as time passes, their narrative becomes less and less concrete product-oriented
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but still the questions to the follicle remain. suppose you have a Norwood 7 for 3-4 years, you start to be treated with Follica. By injury (device 1) you have hair and cosmetically covers your head. What happens next? How long will support work
these hair? Minoxidil for many does not work in 3-5 years. topical seti or finasteride?
someone tells me that these new hair will not fall out, but then why is the device 2 with a massage applicator for applying medicines?
and in general why at the upcoming congress Cotswarelis will talk about PRP?
these hair? Minoxidil for many does not work in 3-5 years. topical seti or finasteride?
someone tells me that these new hair will not fall out, but then why is the device 2 with a massage applicator for applying medicines?
and in general why at the upcoming congress Cotswarelis will talk about PRP?
It's not really definitively known why that is. There is a reason why it would work for some people and not others. But wounding studies that have employed it have definitely had more success than just minoxidil patients, so it stands to reason minoxidil by itself may not be enough for most people. We can also determine they will be using at least two compounds from the info on the site. So I wouldn't worry about this, honestly.
The only people who may have a study that can answer that is Follica and obviously that information is with the powers that be.
There doesn't seem to presently be a published study that is old enough to determine if the hair is "dht resistant or not". There is a case to be made for "not" since it's being created from the same skin that would have created the original hair, as it's been explained to me. The good news is, that doesn't really matter since for most people, it will still take years to lose that hair again and the process can be done again.
I know occulus insists that it wouldn't make a NW4 a NW1 again, but I personally can't find any reason why it theoretically couldn't.
As far as I can tell, wounding neogenesis should work anywhere across the scalp and I've yet to see any sort of argument as to why repeated treatments wouldn't continue to produce more hair after the fact. There just doesn't seem to be any study that's gone on near long enough to really see what the endgame of this is. It's more like they just go for a few weeks or a couple months and then follow up a few months later and are like "yeah it worked".
The good news is that despite wounding + minoxidil taking a primitive form in these studies, there have been some truly fantastic results from it; certainly better than what most of us could hope for from conventional treatments.
But it's a shame that no one has bothered to really follow through with it to see what the upper limits of it could be, and I'm pretty excited to see what a more advanced, well-researched form of the procedure can offer.
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Please, sorry for my long post, this one
I don't want to mislead you, I just want to give you some informations
It's hard to say for sure if it will be minoxidil. But on their patent, they have tested differents compounds like Bimatoprost on their clinical trials .
We can say that they have several compounds for the first generation. @That Guy has explained very well
Here, they have already "completed its clinical-stage development of a next-generation device and drug combination product "
So they have a drug combination product = the first generation of compounds.
It's nice to see that they are already on the next generation of compounds.
Here we can read an interview of Daphne Zohar :
" we are using existing compounds previously approved for systemic chronic use and reformulating them for topical acute use. We know these compounds are safe in people."
There's no questioning the market demand. A new therapy that could safely and effectively treat male and female pattern hair loss would swiftly seize a huge market. And Zohar says the same technology can potentially be applied to hair removal, skin pigmentation and more. But don't ask her to name the original compounds the company is reformulating for novel use - that's a trade secret for now."
So Follica have reformulated the existing compounds
Source: https://www.fiercebiotech.com/special-report/emerging-drug-developer-follica
What do you think about their previously timeline ? they expected to have a regulatory clearance (an FDA approval at the end of 2017 ?) . A short timeline.
View attachment 85831
We don't know the relationship between Follica and the FDA. Maybe they have a " Fast Track designation"
"
A drug that receives Fast Track designation is eligible for some or all of the following:
- More frequent meetings with FDA to discuss the drug's development plan and ensure collection of appropriate data needed to support drug approval
- More frequent written communication from FDA about such things as the design of the proposed clinical trials and use of biomarkers
- Eligibility for Accelerated Approval and Priority Review, if relevant criteria are met "
More details on what is a Fast Track : https://www.fda.gov/ForPatients/Approvals/Fast/ucm405399.htm
Hahaha
LMAO
Maybe Kythera ? According to puretech, Doctor Cotsarelis is a founder of Kythera.
View attachment 85830
Hey Noisette, thanks again
Do you have any idea if this treatment could work on FUE/FUT scars or in somehow scarred areas?
Baldybald1
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Hey Noisette, thanks again
Do you have any idea if this treatment could work on FUE/FUT scars or in somehow scarred areas?[/QUOTE
Yes it will work
Baldybald1
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So here is the thing, the current compounds will be better than the available treatment like 3 or 4 times more. The next t generation compound will give a full head of hair.
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yeah that was a blatant lie
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No way! So it turns out Cotsarelis is not only one of the founders of Follica, but also Kythera, the company running setipiprant trials (which I’m taking at the moment). This man is a hair loss hero haha.
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Dude that's pretty good for his age. Almost 60 with an intact hair line and like a NW3v? I'd easily trade with him. He's not bald. He's balding still, at his age. If he pulls off Follica, then he can probably fill that spot within a year.
br1
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Sorry but that is "bald" not balding. He's bald.
hanginginthewire
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