RIKEN Announcement: Succeeded in Developing Tech for HF Regenerative Medicine: Study to be Published Feb 10

[jan_miezda]

Into "clinics" does not mean actually into doctors offices, it means human trials in general. Small scale testing on humans would be phase 1 trails, the same process Stemson will go through.

But what business model have they presented after performing clinical trials? Stemson has a clear one where tsuji just appears to be focused on research

what exactly will they do if they prove successful HM in humans? They have mentioned human application, but that’s about it whereas Stemson has mentioned in their presentations their goal to work with current transplant clinics to deliver this sort of tech

 

[Pls_NW-1]

But what business model have they presented after performing clinical trials? Stemson has a clear one where tsuji just appears to be focused on research

Stemson hasn't started even pre-clinical trials. They are just about to start series A.

Tsuji works in an institute, public does not need to know everything in detail, whereas Stemson Therapeutics is a private company.

Hope I haven't said something wrong. Correct me, if so.

 

[jan_miezda]

Stemson hasn't started even pre-clinical trials. They are just about to start series A.

Tsuji works in an institute, public does not need to know everything in detail, whereas Stemson Therapeutics is a private company.

Hope I haven't said something wrong. Correct me, if so.

Even stemsons research is associated with a public institute (Sanford).

“The sources of funding in 2019 were: 58% federal; 22% private philanthropy; 8% biopharma partnerships; 8% licensing & other and 4% other grants.”

 

[Pls_NW-1]

Even stemsons research is associated with a public institute (Sanford).

Correct! I am sorry for those missleading informations. It's good to see that many companies and institutes are contributing to this!

 

[jan_miezda]

Correct! I am sorry for those missleading informations. It's good to see that many companies and institutes are contributing to this!

I think stemsons research is done at Sanford but their startup is not affiliated with them or it belongs to them and Allergan has very little stake in their company. Tsuji has not even developed a start up and stemson isn’t publically traded so they must have had a unique/lucky deal with allergan.

 

[Bf20]

"I wrote to the RIKEN team and suggested using GoFundme or contacting Allergan for investment. The latter has invested in 4-5 hair loss companies in recent years. Allergan gave $25 million to Exicure. And potential milestone payments of $265 million. RIKEN needs $4.8 million.

Surprisingly, RIKEN replied to me right away. They were interested in my introducing them to the Allergan team, so I will need to figure that one out! More importantly, they said that they have created the below two links for those who want to donate:"

Hair Loss Cure 2020 | Hair loss blog with the latest news updates.

Stay up-to-date on the latest breakthroughs in hair growth and regeneration. Get key insights on hair loss cures at Hair Loss Cure 2020.

www.hairlosscure2020.com

lol, but allergan would be nice.

Correct me if i'm wrong but i don't believe they actually invested in Exicure, rather they made a intent to invest?

 

[eeyore]

Even stemsons research is associated with a public institute (Sanford).

“The sources of funding in 2019 were: 58% federal; 22% private philanthropy; 8% biopharma partnerships; 8% licensing & other and 4% other grants.”

Where did you get those numbers from?

 

[trialAcc]

Stemson hasn't started even pre-clinical trials. They are just about to start series A.

Tsuji works in an institute, public does not need to know everything in detail, whereas Stemson Therapeutics is a private company.

Hope I haven't said something wrong. Correct me, if so.

Hmm? Series A is an investment round. They've 100% started pre-clinical trials, they just havn't completed them.

 

[trialAcc]

But what business model have they presented after performing clinical trials? Stemson has a clear one where tsuji just appears to be focused on research

what exactly will they do if they prove successful HM in humans? They have mentioned human application, but that’s about it whereas Stemson has mentioned in their presentations their goal to work with current transplant clinics to deliver this sort of tech

The fact that Stemson is integrating business development into the process is exactly how these types of companies should operate. The amount of therapeutics and drugs that fail trials because of the business side of the process is high. These guys would be infinitely better off if they developed a strategic partnership to bring this to market, because at this rate the process of getting this commercialized could extend this for years.

 

[Pls_NW-1]

I think 2022 will be the year we long for. Tsuji, Stemson and Tissuse should start. We should have a cure by 2027. The next generation has it very well

_fingers crossed_

 

[eeyore]

I think 2022 will be the year we long for. Tsuji, Stemson and Tissuse should start. We should have a cure by 2027. The next generation has it very well

As much as I'd love for there to be three possible cures we can look forward to, Tsuji and Tissuse seem a bit too sketchy. With Tissuse it's been one excuse after another and with Tsuji it's just been weird. Years of silence then you have some sketchy Twitter account desperately trying to hype themselves up and asking for donations, something doesn't add up. Stemson might fail just like the rest and go silent but they at least seem to have a grasp on a long term plan for commercialization.

 

[jan_miezda]

in reality, Tsuji didn’t go silence for that long after organ failed and during the pandemic.
It’s just that we watch his every move and expect too much things to happen to quickly

plus now we know his publication was pending acceptance for about 6 months

 

[pegasus2]

As much as I'd love for there to be three possible cures we can look forward to, Tsuji and Tissuse seem a bit too sketchy. With Tissuse it's been one excuse after another and with Tsuji it's just been weird. Years of silence then you have some sketchy Twitter account desperately trying to hype themselves up and asking for donations, something doesn't add up. Stemson might fail just like the rest and go silent but they at least seem to have a grasp on a long term plan for commercialization.

Yes, those sketchy companies pulled the wool over Kyocera and Bayer's eyes. Can we stop with the conspiracy theories

 

[jan_miezda]

AAAS

advances.sciencemag.org

a different publication by their team on the same day? they have been working hard in silence

 

[Gegen]

Samumed Closes on $438 Million in Equity Financing

SAN DIEGO, Aug. 06, 2018 (GLOBE NEWSWIRE) -- Samumed, LLC, announced today that it has closed its A-6 Round of equity issuance with $438 million,...

www.globenewswire.com

Tsuji: We need 4.8 million so we can restore all of your hair. Density, color, direction of growth
438 M: Hey, who wants 10 % regrowth in 3 months?

Bad comparison. In august 2018 Samumed prepared an important phase 3 study with +640 participants and multiple centers, employees, administrative sh*t with FDA and Turkey, etc...For Tsuji it's more simple as they already have the support of Japan government, and he doesn't need to do a huge phase 3 study with hundreads participants.
A more honest comparison would be to compare the cost of phase 1 trial for SM04554 and that of the future trial of Dr.Tsuji. And even doing that the comparison would still be wrong.

 

[Gegen]

I´m just joking
they also have many other products in the pipeline

I guess I'm a little tired this evening lol.

 

[czecha]

it just doesn't add up that 5 mil is a problem when you can offer a hairloss cure imo, or even something that is just promising. this tech could make several hundred billion.
it has got to be a scam, and desperate hair loss sufferers will ofc throw money at everything

can someone tell me how this makes any sense from a investment/business perspective?

 

[waynakyo]

it just doesn't add up that 5 mil is a problem when you can offer a hairloss cure imo, or even something that is just promising. this tech could make several hundred billion.
it has got to be a scam, and desperate hair loss sufferers will ofc throw money at everything

can someone tell me how this makes any sense from a investment/business perspective?

I think I answered your question earlier.
It is because you have an idea that is worth a billion dollar and you have no money on you, you WON't accept money from an investor, to take 10% stake in exchange of 10M$. It does not make sense. So you rely on friends, family, and reach out to people who care in your business.

Now again Riken is not a business. So that was a hypothetical. But if they are interested in partnership right now there is too much uncertainty for investors to offer a good deal. Remember they know more than we know about the chances of their technology.

Anyway, even if they turn out to be crooks (they published this in a great journal) I don't know how much people would regret donating 50 bucks.

I don't get it. People here treat their hair as if it is their life, guilty of that too, what is the big deal of spending SOME money on it?

no... instead let's just sit and complain.

 

[pegasus2]

If you told anyone in the world that you have the cure for hair loss, and you've already tested it in a human, and received regulatory approval to conduct clinical trials for commercialization, and the only thing stopping you is that you need 4.8 million dollars to do it, nobody would believe you. Yet here we are.

Tsuji is definitely not a scammer. Read his research yourself. It's solid work, and he's an eminent Japanese researcher. Honor and integrity aren't hollow words in Japan even in the 21st century. Seppuku is still a thing there. If you notice they haven't tweeted today. I'm guessing they've received some serious inquiries.

 

[czecha]

I think I answered your question earlier.
It is because you have an idea that is worth a billion dollar and you have no money on you, you WON't accept money from an investor, to take 10% stake in exchange of 10M$. It does not make sense. So you rely on friends, family, and reach out to people who care in your business.

Now again Riken is not a business. So that was a hypothetical. But if they are interested in partnership right now there is too much uncertainty for investors to offer a good deal. Remember they know more than we know about the chances of their technology.

Anyway, even if they turn out to be crooks (they published this in a great journal) I don't know how much people would regret donating 50 bucks.

I don't get it. People here treat their hair as if it is their life, guilty of that too, what is the big deal of spending SOME money on it?

no... instead let's just sit and complain.

I get that but if you have to relocate like 2 % of your companies yearly budget to bet on your own billion dollar idea it's a no brainer