Just a few updates. Still needling 3-4x a week, and sparingly using retin-A 1x a week. I continue making progress with newly established hairs getting thicker, and an increase in overall density. My vertex has really started to respond, and my natural hairline is absolutely amazing now. I hardly shed at all, even in the dead of winter. And sometimes have gone days without any topical application to no ill effect.
I'm also getting lots of compliments about my hair and general appearance. Friends, acquaintances, and family ask what, if anything, is being done differently. They immediately notice any changes in hairstyles and haircuts; it's very gratifying. That rarely happened when my regimen was just minoxidil and finasteride; although during that time my hair was ratty and flat, instead of full and dense.
Facilitating WNT signaling through needling/wounding/supplements, and then increasing the proliferation of stem cells seems to be the most potent combination for hair follicle regeneration. Therefore, one of the biggest and best changes to my topical regimen has been the inclusion of stem cell proliferators, based on this research paper.
http://www.naturatherapeutics.com/image ... icle_1.pdf
I've also eliminated the more smelly and staining supplements, and tried to hone overall effectiveness and reduce redundancy. The entire topical concoction takes me five minutes to make every two months. Most of these supplement powders can be had very cheaply at beyondacenturyonline.com.
topical stem cell proliferators
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carnosine
green tea extract
vitamin D3 (gelcaps)
wild blueberry extract
resveratrol
DHA
(considering adding blue green algae)
minoxidil
bioperine (increases bioavailability, potential (?) to increase anagen phase)
caffeine (slightly redundant when included w/ green tea extract, anti-androgenic activity)
melatonin (increases anagen hair rate)
msm (increase penetration and absorption)
rosemary extract (decrease inflammation, potent COX-2 inhibitor) or holy basil (very smelly)
niacin (increases capillary action)
superoxide dismutase (breaks down superoxide, decreases oxidative stress and potential damaging effects of minoxidil)
nattozimes or serrazimes (reduce inflammation, breaks down fibrin, increase WNT signaling)