South Korean Scientists Has Developed A New Type Of Biochemical Material To Prevent Hair Loss
- Thread starter Xaser94
- Start date
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- 126
Seems you didn't used PTD-DBMI use approx 2years VPA+Microneedling........Not a single result
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- 1,253
Hey Guys! Me and @CureOrDeath have gotten a reputable Western peptide maker to make PTD-DBM!
We had a lot of buyers but 20 vials short due to short notice and some drop outs.
It’s $115 for 20 mg, which you can use this at .3 mg a day.
This is a new thing, but we are the only ones in the world with the peptide!
Please PM us so we call sell the 20 leftover vials!
We had a lot of buyers but 20 vials short due to short notice and some drop outs.
It’s $115 for 20 mg, which you can use this at .3 mg a day.
This is a new thing, but we are the only ones in the world with the peptide!
Please PM us so we call sell the 20 leftover vials!
Do they have it ready to ship soon?
Nobody else has tried this yet
- Reaction score
- 126
No they make it only for us, manufacture process requires few weeks.
No one has tried it becase it's impossible to find a legit manufactuer, you can pm if you are interested I can give you more info.
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- 1,126
PM me please. Could be interested in this.
Sanchez1234
Experienced Member
- Reaction score
- 311
I can't believe people are not hyped for this...
A lot of people are, but again, there's not any proof it works, not yet at least
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- 521
What phase is this in? Has it been tested on humans yet? Will it be available to us in the next 5 years?
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- 421
Are testers going to create a thread for follow-ups?
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- 421
Thanks a lot! By the way, are you just planning on doing it a month (as in the study) or go further than that. As you probably know, mice and human hair cycles are different
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- 51
Trying to find something that is already on the market here:
Lee et al. revealed that the actions of CXXC5 required Dishevelled (Dvl), a mediator of Wnt ligand signaling; by binding Dvl, CXXC5 promotes β-catenin degradation. The regenerative effects of CXXC5 were identified to be largely mediated by the β-catenin target gene endothelin-1 and therefore could be blocked by the endothelin receptor inhibitor, bosentan.
http://stm.sciencemag.org/content/7/297/297ec125
Yet when researching Bosentan, it doesn't seem good for our hair since it works on COX1 & 2.
Also de molecular mass is above 500...
While three endothelin receptor antagonists (bosentan, sitaxentan and ambrisentan) are already available for the treatment of pulmonary arterial hypertension
https://www.ncbi.nlm.nih.gov/pubmed/19517317
In 2010, Pfizer voluntarily removed sitaxentan from the market due to concerns about liver toxicity.
So forget about that one.
Ambrisentan, which relaxes those muscles, is an endothelin receptor antagonist, and is selective for the type A endothelin receptor (ETA)
https://en.wikipedia.org/wiki/Ambrisentan
It is also a small molecule with 378.421 g/mol molecular mass.
Im just not sure if this type A receptor is any good. And if this stuff is safe enough topically for instance.
Lee et al. revealed that the actions of CXXC5 required Dishevelled (Dvl), a mediator of Wnt ligand signaling; by binding Dvl, CXXC5 promotes β-catenin degradation. The regenerative effects of CXXC5 were identified to be largely mediated by the β-catenin target gene endothelin-1 and therefore could be blocked by the endothelin receptor inhibitor, bosentan.
http://stm.sciencemag.org/content/7/297/297ec125
Yet when researching Bosentan, it doesn't seem good for our hair since it works on COX1 & 2.
Also de molecular mass is above 500...
While three endothelin receptor antagonists (bosentan, sitaxentan and ambrisentan) are already available for the treatment of pulmonary arterial hypertension
https://www.ncbi.nlm.nih.gov/pubmed/19517317
In 2010, Pfizer voluntarily removed sitaxentan from the market due to concerns about liver toxicity.
So forget about that one.
Ambrisentan, which relaxes those muscles, is an endothelin receptor antagonist, and is selective for the type A endothelin receptor (ETA)
https://en.wikipedia.org/wiki/Ambrisentan
It is also a small molecule with 378.421 g/mol molecular mass.
Im just not sure if this type A receptor is any good. And if this stuff is safe enough topically for instance.
PTD-DBM and vpa.