Too difficult to make, too expensive and no safety data whatsoever in humans.
We need other inhibitors for it. Meanwhile ppl could give melatonin a honest try:
Estradiol-Estrogen Receptor α Mediates the Expression of the CXXC5 Gene through the Estrogen Response Element-Dependent Signaling Pathway
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122896/
Melatonin, an endogenous-specific inhibitor of estrogen receptor alpha via calmodulin.
https://www.ncbi.nlm.nih.gov/pubmed/15229223
Agreed, 23andme/ University of Bonn - (in 22000 men genetic data) found deficit melatonin signaling gene as one of the prominent markers for balding men. So definitely worth a try