brian asked:
barry like to ask you how can one be sure that spraying something that stimulates hair growth on part of body OTHER than scalp can be guarranteed NOT to be andriogenic in nature
Ive run alot of little self tests on my body hair (Im hairy) in the past, and two have suprised me because the effects were the opposite of what I expected.
The two were nizoral shampoo and lavendar. I washed one wrist in nizoral, let it stay on for about one minute before rinsing, for about three months when I showered. Results? The wrist hair got a little longer and darker...........which was completely contrary to my expectations.
The second suprising topical was lavendar oil. I put it on the hair on my right big toe. I expected less hair. I got hair that was longer and darker than the other toe in about three months.
Something in ketoconazole and something about lavendar might be stimulating to hair follicles. Estrogen supposedly hair a role in the hair cycle, and perhaps lavendar might mimic it to an extent, but then again it might simply be a stimulant or a anti-infalmmatory or it may help inhibit some negative growth factor secreted by the papilla. I really dont know. What I do know is that lavendar is in alot of the old "essential oil" hair growth remedies from the past. I used to laugh at these things, but ever since becoming aware of beta sitosterol, and consequently finding out beta sis is in revivogen and its highest concentration is in pine or cedarwood oil---an essential oil in alot of old hairloss remedies-----I started looking into these substances. Ive since found out that rosemary is a good anti-inflammatory, pine oil (beta sis) is anti-androgenic, lavendar oil stimulates hair in "some unknown" way, and that thyme and sage keep showing up in shampoos from companines like American Crew and Paul Mitchell that I respect. Maybe these things will be found to up pro-growth factors or help inhibit anti-growth factors secreted by the papilla, or fight oxidization (rosemary) or supress immuno responses, but thousands of years of human experimentaion might have yielded some fruit that I was heretofore willing to overlook.
You know these essential oil blends were written off by science basically based on hair transplant infomercials in the seventies and eighties. We were told by authoritative-sounding narrarators that there was "nothing unitl now that can be done about hair baldness", and that all other remedies were bunk and snake oil. Damn near, of course, were bunk and snake oil................but there might have been something to the remedies from the natural oils that anyone could obtain for almost nothing from plants.
My goal all along has been to find something to "add" to my finasteride and prox-n. I think I might have found it in peppermint oil (although licorice might be even stronger). Other than that................Im waiting on cloning pretty anxiously at this point.
Intercytex may have something in the next couple of weeks. They are actually paying for the next ISHRS convention in Los Vegas, so they may really have had some nice experimental results to share (and I hope they do).
Back to the anti-androgens.....................We know free form GLA, ALA, and other fatty acids can be anti-androgenic, but its expensive and beyond kitchen sink chemistry to obtain them. Ive long thought, that out of all the natural chemicals of all the plants in nature, surely one will have an affinity for the androgen receptor and surely more than one will be a good chemical fit to bind-with the alpha five reductase enzyme in such a way as to inhibit it from reacting with testosterone. In truth, there are probably more than one..................peppermint, licorice, clove, perhaps spearmint, rose hips, variouis flower, perhaps some compounds in various tea leaves, and who knows how many more weeds out there in exotic places we dont know about........................Nature is virtually full of exotic chemcals in the forrests and jungles. Thats where so many pharmaceuticals actually come from. Compounds within natural chemicals are isolated and patented, and sold. Blueberries for instance, are probably the healthiest fruit one can eat (and thats very healthy indeed), they have alot of super chemicals and anti-oxidants within them.............Ive no doubt companies will be looking to break these down into individual chemicals that the can recreate in the lab, test, and patent for various ailments. It would be just as good to eat the damned blueberries though........................
Hope everybody has a great weekend chasin' the babes.
