timi,you were right all along

Andrea

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I've been on Proscar about 2 years, than I switched Duta and now I' on 8th month...
 

JWM

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Dr. Reddys sells Dutas not Veltride. Dutas is a gel capsule.

So your hair is doing good on ONE dutasteride pill a week?
 

CCS

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I was on finasteride 4 years, and I think it maintained my hair pretty well. Then I switched to dutas EOD, and I think I lost some hair, though maybe it seemed that way after the surgery, or maybe I had shock loss. Now I'm back on finasteride. But I think my topicals have thickened my hair. That or my new hair cut lets the hairs lay pretty well.


As for the frontal hair line, they did not count hairs there, but they did look at photo graphs. In the 2.5mg/day group, they said they saw an improvement in the hairline. That's enough for me. They did not notice a diference between 0.5mg and proscar in the pictures.
 

mulder

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I really don't understand why more people don't just add a low dose of dutasteride to their finasteride regimen...
 

Pondle

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mulder said:
I really don't understand why more people don't just add a low dose of dutasteride to their finasteride regimen...

I don't think dutasteride's performance at low doses is anything to write home about. And you get the best levels of DHT inhibition when you take a daily dose and allow sufficient time for the drug to build up in your system.
 

SkylineGTR

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my hairline in the front has improved. But I also supplement with minoxidil.
 

Andrea

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One or two caps/week is the right dosage!
A larger dose caused Telogen Effluvium in some people...
In our forum a guy says that he visited by Dr Wong in Vancouver (Hasson and Wong) and the Doctor prescribe him two caps Avodart (Glaxo)/week...
The guy says that so far (9 month) nothing regrowth but the hairs looks wonderfoul and he never had shedding...
x JWM: Sorry, solid Duta is Veltride by Genhair...
Bye
 

Pondle

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Andrea, I don't think they tried that dose in the Avodart hair loss trial. If you want maximum DHT inhibition, you have to take 0.5mg/day or up to 2.5mg/day.

FinvsDutcomparison.jpg


dutaslevels.jpg
 

Andrea

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Well,
the inibitors of 5 Alpha Reductase are dose-dipendent, more drug more results, there is no doubt...
But Dutasteride is a drug with a long life in the blood and if you don't tolerate 0,5mg die you can take 1 or 2 caps/week and obtain result better than finasteride everyday.
The inibition of DHT in the blood is not important in male pattern baldness, but is VERY IMPORTANT tht the drug works in the FOLLICLE!
 

Pondle

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Andrea said:
Well,
the inibitors of 5 Alpha Reductase are dose-dipendent, more drug more results, there is no doubt...
But Dutasteride is a drug with a long life in the blood and if you don't tolerate 0,5mg die you can take 1 or 2 caps/week and obtain result better than finasteride everyday.
The inibition of DHT in the blood is not important in male pattern baldness, but is VERY IMPORTANT tht the drug works in the FOLLICLE!

I'm not sure if taking one or two caps a week is really sufficient. When you have low doses of dutasteride, the performance is pretty similar to finasteride. I added the low doses of dutasteride to my chart of the phase II Avodart hair loss trial. Somebody also wrote that the half-life is partly dependent on the dosage? I don't know enough about pharmacology to make sense of that.

DutversusfinincludingPropecia-1.jpg
 

purecontrol

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Why can't they inhibit more than a max of 55% of DHT in the scalp, IMO the serum and scalp levels are backwards from where they need to be.
 
T

Timi

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one 0,5Dut in the week is so good as 1mg finasteride Dayli
but dutasteride is for Typ1+2 and thus better

Pondle i have take dutasteride-finasteride Kombi März 2006-Nov.2006

finasteride Dayli and dutasteride all 4-5Days (0,5mg)
i had Hairs become there was 5Years nothing more

i take finasteride and dutasteride!! Steady State under finasteride is to reach more easily
with less side effects

and dutasteride for a Longtime work

under 0,5mg dutasteride Dayli i have big side effects!!

Timi
 

Andrea

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Timi now your hair is good?
With this regimen in your board there are some good results?
What do you mean when you say: I had hairs become there was 5 years nothing more... It' positive or negative?
Thanks!
 
T

Timi

Guest
Andrea said:
Timi now your hair is good?
With this regimen in your board there are some good results?
What do you mean when you say: I had hairs become there was 5 years nothing more... It' positive or negative?
Thanks!

The Hairs with Stop minoxidil get better
to Good is a long Way

Good was my Hair March 2006-November2006
with finasteride-dutasteride kombie
and Hairs become there was 5Years nothing more (Hairline)

i begun minoxidil for the corners Nov.2006 and the Desaster
begun!
all Hairs in the Front very fast thinning out 10Month and no Hairs come back

Timi
 

Devlin

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Reducing Avodart to a Lower doss

Upto Feb 25th I had been taking Propecia 6 days per week, plus Regaine regular strength morning and evening. Results were very positive in that although hair in temples and frontal areas never returned to that of my youth (I'm now 36years old), they did not deteriorate and the top of my scalp more or less returned to it's original condition. However, to try and improve my temples and frontal area (I have a small bump on my forehead, so I like to have a fringe) I began taking Avodart as follows:

Feb 25th 2006 – Begin taking 0.5mg Avodart.

1st March 2006 – Stop using Regaine Regular and Propecia.

Beginning of April 2006 – Start using Regaine Extra Strength having noticed that I can brush lots of hair into the sink. Apparently, it takes 90 days for the Avodart to reach maximum levels in the body. Maybe I shouldn't have stopped taking Propecia so suddenly?

June 25th 2006. – I have been taking Avodart 0.5mg per day for nearly 4.5 months. Thinning on top of scalp definitely noticeable under light bulb, but seems to have improved temples and frontal areas (or is it just that they look better when compared to the top of the scalp??)

Stopped taking Avodart and began taking Propecia again. Hair returned to normal.

Took Avodart three times per week with a daily Propecia from the middle of Sep 2006 until the 23rd Nov 2006, to help maintain what I perceived as an improvement in growth around the temple and frontal areas. Hair maintained its health and thickness this time. Can't swear to significant improvement in frontal and temple areas though.

From end of Nov 2006 to second week in February 2007 took Propecia and Regaine Regular as prescribed.

Second Week in February 2007 to 19th June 2007 (4 months) stopped taking all hair loss products apart from Regaine Regular Strength. Apart from around the temples and right at the front of the scalp, no noticeable difference in hair loss. Even at the front and temples it was not marked, just a slight deterioration.

19th June 2007 – Began taking 2 Avodart per day, plus 1 Propecia, in addition to normal Regaine Regular strength treatment. I feel that Avodart helps re-grow the hair around the temples and frontal area.

9th Sep 2007 – Took 2x0.5mg Avodart + Propecia per day from the 19th June to 24th July, plus Regaine Regular, then just took Propecia during my stay abroad (from 25th July to 6th August). From 6th August to 9th Sep took 1 Avodart 0.5mg and 1 Propecia plus Regaine Regular. In terms of hair pattern, I have noticed an increase in the amount of hair that I shed into the sink and that I am beginning to thin a little just back and very slightly in from the temple area. I think that I have also thinned a little on top but not as much as last year when I took just Avodart on its own. The hair is also becoming noticeably dry and 'strawlike'.

Having read Andrea's post I think that I am going to stop taking Avodart for about a month and remain on Propecia + Regaine regular. Will then look at taking just one or two Avodart capsules per week.

All in all, my little study in not particularly scientific and probably too emotionally driven, but as other people have mentioned, Avodart seems to cause shedding and poor quality hair in the initial stages. Trouble is, I haven't seen many posts to convince me that it's worth waiting 12 months to see if it does work in the end!
 

Andrea

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At this time the sinergy between fina and duta (low dose) seems to show best results...
 
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